Copyright ©The Author(s) 2018.
World J Methodol. Nov 29, 2018; 8(3): 17-36
Published online Nov 29, 2018. doi: 10.5662/wjm.v8.i3.17
Table 3 Allergen molecules of domestic insect pest origin1 used in singleplex and multiplex immunoassays[9,74,104]
Allergen moleculeBiological function, comments, CR
Cockroaches (Blattella germanica, Periplaneta americana)
rBla g 1Midgut microvilli protein-homolog CR Per a 1 (group 1),
secreted in the digestive system and excreted in fecal particles,
concentration in feces of adult females higher vs adult males and nymphs
rBla g 2Unusual inactive aspartic protease with strong allergenic properties
Digestive organs (esophagus, gut and proventriculus) and fecal particles
rBla g 4Insect calycin lipocalin, calcium binding protein,
binds tyramine/octopamine with role in reproduction of insects
rBla g 5GST
Involved in detoxification of toxic compounds role in insecticide resistance
rPer a 7Invertebrate tropomyosin, muscle contraction protein,
invertebrate panallergen CR Bla g 7, locomotor insect body parts