Methods, units and quality requirements for the analysis of haemoglobin A1c in diabetes mellitus

Figure 1 Fractionation of blood hemoglobin by an automated Mono S™ HR5/5 cation exchange column from Pharmacia with malonate buffer (0. 01 mol/L, pH 5.7, 11 min, room temperature) for normal and diabetic human blood samples is illustrated as a chromatogram (Penttilä et al[10]).

Figure 2 The total variations of the glycohemoglobin results have been presented both in % and in mmol/mol units from the surveys of Labquallity Ltd. from 1994 to 2015. In the part A have been presented the total variations of the glycohemoglobin in % units and in the part B the total variations of HbA_1c in mmol/mol units.