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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Jun 26, 2015; 5(2): 62-67
Published online Jun 26, 2015. doi: 10.5662/wjm.v5.i2.62
Published online Jun 26, 2015. doi: 10.5662/wjm.v5.i2.62
Neurally adjusted ventilator assist in very low birth weight infants: Current status
Hassib Narchi, Department of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain PO Box 17666, United Arab Emirates
Fares Chedid, Department of Pediatrics, Al Jalila Hospital, Dubai Health Authority, Dubai PO Box 4545, United Arab Emirates
Author contributions: Both Narchi H and Chedid F had made substantial contributions to conception and design of the editorial, drafting the article or making critical revisions related to important intellectual content of the manuscript and final approval of the version of the article to be published.
Conflict-of-interest: The authors have no commercial, personal, political, intellectual, or religious conflict-of-interest to report in relation to this work.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Fares Chedid, MD, Department of Pediatrics, Al Jalila Hospital, Dubai Health Authority, Dubai PO Box 4545, United Arab Emirates. fareschedid@hotmail.com
Telephone: +971-50-4474661
Received: December 25, 2014
Peer-review started: December 30, 2014
First decision: February 7, 2015
Revised: March 7, 2015
Accepted: April 10, 2015
Article in press: April 14, 2015
Published online: June 26, 2015
Peer-review started: December 30, 2014
First decision: February 7, 2015
Revised: March 7, 2015
Accepted: April 10, 2015
Article in press: April 14, 2015
Published online: June 26, 2015
Core Tip
Core tip: Neurally adjusted ventilator assist (NAVA) ventilation utilizes the patient’s neural respiratory drive to synchronize ventilatory support on a breath-by-breath basis based on the infant’s ongoing needs. It appears to work well in neonates but evidence that it makes a difference in outcomes in this population has not been established so far. The majority of studies have shown no significant adverse events in neonates ventilated with NAVA nor a difference in the rate of intraventricular hemorrhage, pneumothorax, or necrotizing enterocolitis when compared to conventional ventilation. The challenge for neonatal health care providers remains the steep and prolonged learning curve for the application of NAVA.