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Prospects and advancements in C-reactive protein detection
Pranjal Chandra, Pankaj Suman, Himangi Airon, Monalisa Mukherjee, Prabhanshu Kumar, Biomimetic Research Laboratory, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida 201303, India
Author contributions: All the authors made a substantial contribution to the conception and design of the manuscript, drafting and revising the article.
Correspondence to: Pranjal Chandra, Assistant Professor, Biomimetic Research Laboratory, Amity Institute of Biotechnology, Amity University Uttar Pradesh, J-3 Block Sector-125, Gautam Buddha Nagar, Noida 201303, India. pchandra1@amity.edu
Telephone: +91-120-4392644 Fax: +91-120-4392295
Received: November 19, 2013
Revised: January 13, 2014
Accepted: February 16, 2014
Published online: March 26, 2014
Revised: January 13, 2014
Accepted: February 16, 2014
Published online: March 26, 2014
Core Tip
Core tip: Over time, C-reactive protein (CRP) has emerged as a versatile marker for the detection of systemic inflammatory conditions, providing preliminary information to clinicians for continuing with a more specific diagnostic methodology. Advancements in electroanalytical chemistry and knowledge of nanomaterials have helped modern age researchers to miniaturize detection systems with an enhanced level of specificity and sensitivity of CRP detection. Further research should be directed in this area to devise a better diagnostic platform that can detect the change in CRP level at a very early stage of the onset of inflammatory conditions.