Crohn's disease and clinical management today: How it does?

doi:10.5662/wjm.v13.i5.399

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World Journal of Methodology

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Dec 20, 2023; 13(5): 399-413
Published online Dec 20, 2023. doi: 10.5662/wjm.v13.i5.399

Crohn's disease and clinical management today: How it does?

Ronaldo Teixeira da Silva Júnior, Jonathan Santos Apolonio, Jessica Oliveira de Souza Nascimento, Bruna Teixeira da Costa, Luciano Hasimoto Malheiro, Marcel Silva Luz, Lorena Sousa de Carvalho, Cleiton da Silva Santos, Fabrício Freire de Melo, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista 45029-094, Bahia, Brazil

Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.

Conflict-of-interest statement: No potential conflicts of interest,and no financial support.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Fabrício Freire de Melo, PhD, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormínio Barros, 58, Candeias, Vitória da Conquista 45029-094, Bahia, Brazil. freiremelo@yahoo.com.br

Received: September 22, 2023
Peer-review started: September 22, 2023
First decision: September 29, 2023
Revised: October 11, 2023
Accepted: October 25, 2023
Article in press: October 25, 2023
Published online: December 20, 2023

Core Tip

Core Tip: Today, the clinical management of Crohn's disease (CD) involves both non-pharmacological and pharmacological therapies with the primary objective of inducing and maintaining remission. In this context, anti-inflammatory drugs, including corticosteroids, immunomodulators, and biological agents, can be employed either as monotherapy or in combination. Surgical treatment, while considered palliative, is not curative. Therefore, this review aims to provide an overview of current evidence regarding interventions for CD.