1
|
Abdishakur AE, Ahmed MAA. Adult ileo cecal intussusception as a manifestation of colon carcinoma: A case report. World J Clin Cases 2025; 13:104352. [DOI: 10.12998/wjcc.v13.i22.104352] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/17/2024] [Revised: 03/11/2025] [Accepted: 04/09/2025] [Indexed: 05/14/2025] Open
Abstract
BACKGROUND Intussusception is the invagination of a segment of the bowel into an adjacent segment. It is the most common cause of intestinal obstruction in children, but in adults, it is rare, accounting for 1% of all intestinal obstructions and 5% of all intussusceptions, with malignancy being the most common cause. In the past, it was typically diagnosed intraoperatively. However, with the availability of computed tomography for abdominal imaging, recognizing the condition's signs has become crucial. Surgical intervention is essential for managing neoplastic cases and their complications.
CASE SUMMARY A 45-year-old female presented with severe abdominal pain encompassing her entire abdomen, abdominal distension, vomiting, and persistent constipation. Over the past two months, she has also experienced considerable weight loss. After an initial history review, examination, and imaging investigations, the patient was diagnosed with ileo cecal intussusception resulting from a colo rectal mass located in the cecum and ascending colon. This condition was surgically managed through an extended right hemi colectomy.
CONCLUSION Intussusception is uncommon in adults, but it should be considered in patients with intestinal obstruction. Surgical intervention is essential.
Collapse
Affiliation(s)
- Abdihakim Elmi Abdishakur
- Department of General Surgery, Somali Sudanese Specialized Hospital, Mogadishu 274149, Banadir, Somalia
| | - Mohamed Amiin Adan Ahmed
- General Practitioner, ICU Department, Somali Sudanese Specialized Hospital, Mogadishu 274149, Banadir, Somalia
| |
Collapse
|
2
|
Salam A, Chkir B, Haq S, Mansour M. Colocolic intussusception with intestinal obstruction in adults secondary to a colonic lipoma. BMJ Case Rep 2025; 18:e263469. [PMID: 40055017 DOI: 10.1136/bcr-2024-263469] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/13/2025] Open
Abstract
We report the case of a woman in her early 60s, who presented with colocolic intussusception, leading to acute large bowel obstruction. The patient presented with colicky abdominal pain, diarrhoea mixed with blood and mucous and raised inflammatory markers. Abdominal examination revealed mild tenderness in the left lower abdomen. The CT scan reported colocolic intussusception extending from proximal to mid-sigmoid colon, with early ischaemic changes. The patient underwent laparoscopy-assisted sigmoid colectomy with an end colostomy and an uneventful postoperative recovery. Histopathological examination identified a benign colonic lipoma, with ischaemic and necrosed intussuscepted colonic segment. Intestinal intussusception is rare in adults and only accounts for 1% of the cases of intestinal obstruction in adults, mostly caused by a pathological lead point like colonic adenocarcinoma or a benign lipoma. Due to the potential risk of malignancy, radiological decompression is not advisable in adults, and en bloc resection of the intussuscepted segment is recommended.
Collapse
Affiliation(s)
- Ammara Salam
- Manchester University NHS Foundation Trust, Manchester, UK
| | - Baraa Chkir
- Manchester University NHS Foundation Trust, Manchester, UK
| | - Shua Haq
- Manchester University NHS Foundation Trust, Manchester, UK
| | | |
Collapse
|
3
|
Silva C, Gomes da Costa A, Ferreira Á. Jejunal Intussusception Due to an Adenocarcinoma. Cureus 2025; 17:e79219. [PMID: 40115716 PMCID: PMC11925127 DOI: 10.7759/cureus.79219] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 02/17/2025] [Indexed: 03/23/2025] Open
Abstract
Intussusception occurs when a segment of the intestine telescopes into a neighboring part of the bowel. While it is uncommon in adults, unlike in children, when it does occur, a tumor is usually the underlying cause. Here, we report a rare case of a male patient diagnosed with jejunal adenocarcinoma, who initially presented with iron deficiency anemia. Intussusception was identified during surgery, and a laparoscopic resection of the affected jejunal segment was carried out.
Collapse
Affiliation(s)
- Carolina Silva
- General Surgery Department, Centro Hospitalar do Oeste, Caldas da Rainha, PRT
| | | | - Ágata Ferreira
- General Surgery Department, Centro Hospitalar do Oeste, Caldas da Rainha, PRT
| |
Collapse
|
4
|
Lynberg M, Isserman J, Davis JE. Elderly Man With Abdominal Pain. Ann Emerg Med 2025; 85:183-184. [PMID: 39843149 DOI: 10.1016/j.annemergmed.2024.08.002] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/22/2024] [Accepted: 08/05/2024] [Indexed: 01/24/2025]
Affiliation(s)
- Matthew Lynberg
- Department of Emergency Medicine, Georgetown University School of Medicine, Washington, DC
| | - Jacob Isserman
- Emergency Medicine, Georgetown University, Washington, DC; MedStar Health, Washington, DC
| | - Jonathan E Davis
- Emergency Medicine, Georgetown University, Washington, DC; MedStar Health, Washington, DC
| |
Collapse
|
5
|
Craine S, Agarwal S, Al-Hamid Z. Intussusception of Meckel's Diverticulum: A Case Report. Cureus 2024; 16:e76513. [PMID: 39877761 PMCID: PMC11772572 DOI: 10.7759/cureus.76513] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 12/27/2024] [Indexed: 01/31/2025] Open
Abstract
Meckel's diverticulum (MD) is a common congenital anomaly of the gastrointestinal tract, present in approximately 2% of the population. While typically asymptomatic, MD can lead to complications such as obstruction and intussusception. Here, we present a case report of a man presenting with abdominal pain with an incidental finding of MD complicated by intussusception and our management approach. A 39-year-old man with a history of ulcerative colitis (UC) presented with sudden severe right iliac fossa pain, vomiting, and a background of intermittent dull abdominal pain over three months. Examination revealed a tender abdominal mass in the right iliac fossa. Despite his UC history, imaging revealed ileo-ileal intussusception with an inverted MD serving as the lead point, a rare finding in adults. The patient underwent emergency surgery, including resection of the intussuscepted bowel segment and side-to-side anastomosis. Histopathology confirmed ulceration and granulation tissue within the MD. The patient's postoperative course was uneventful, and he was discharged with follow-up care. This case underscores the diagnostic challenge posed by intussusception in adults, especially when overlapping symptoms suggest more common conditions like a UC flare-up. It highlights the importance of considering less frequent diagnoses, such as MD-induced intussusception, in acute abdominal presentations, and reinforces the utility of CT imaging in identifying atypical causes of bowel obstruction. The case also emphasises the need for surgical intervention in symptomatic MD cases to prevent complications.
Collapse
Affiliation(s)
- Saskia Craine
- Obstetrics and Gynaecology, Blackpool Teaching Hospitals, Blackpool, GBR
| | | | - Zaid Al-Hamid
- Colorectal Surgery, Blackpool Teaching Hospitals, Blackpool, GBR
| |
Collapse
|
6
|
Vaidya K, Gharde P, Shinde RK, Patil M, Goel S. Complex Traumatic Jejunal Perforation With Mesenteric Tear and Intussusception: A Case Report. Cureus 2024; 16:e61852. [PMID: 38978904 PMCID: PMC11227980 DOI: 10.7759/cureus.61852] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/02/2024] [Accepted: 06/06/2024] [Indexed: 07/10/2024] Open
Abstract
Blunt abdominal trauma can result in a spectrum of injuries, ranging from superficial contusions to severe hollow viscus perforations. We present the case of a 52-year-old male involved in a bicycle-truck collision, leading to complex intra-abdominal injuries. The patient presented with acute abdominal pain and signs of peritonitis, prompting urgent diagnostic workup and surgical intervention. Imaging studies revealed pneumoperitoneum, free fluid, and multiple rib fractures indicative of significant trauma. Exploratory laparotomy unveiled a perforated jejunal loop with an associated mesenteric tear and intussusception, necessitating segmental bowel resection and repair. Histopathological analysis confirmed acute hemorrhagic inflammation consistent with traumatic perforation. This case highlights the challenges and complexities associated with blunt abdominal trauma, emphasizing the importance of prompt recognition, multidisciplinary management, and surgical intervention in optimizing patient outcomes.
Collapse
Affiliation(s)
- Khushbu Vaidya
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Pankaj Gharde
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Raju K Shinde
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Mihir Patil
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Somya Goel
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| |
Collapse
|
7
|
Sudabattula K, Gattani R, Panchagnula T, Dahmiwal T, Thatipalli N, Sapkale B. Submucosal Lipoma-Induced Small Bowel Intussusception: A Case Study of Surgical Intervention and Management in an Adult Female. Cureus 2024; 16:e62710. [PMID: 39036147 PMCID: PMC11259527 DOI: 10.7759/cureus.62710] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/10/2024] [Accepted: 06/19/2024] [Indexed: 07/23/2024] Open
Abstract
We present an adult patient, a 39-year-old female, with chief complaints of pain in the umbilical region. The patient was further evaluated by radiological investigations and was diagnosed with small bowel intussusception caused by submucosal lipoma as the lead point. She had undergone ileal resection and anastomosis of the affected segment. The postoperative period was uncomplicated, and the patient continued with regular oral intake. The histopathological analysis revealed it to be adipose tissue with no features of atypia. This case shows the rare presentation of small bowel intussusception due to a submucosal lipoma. It emphasizes the significance of diagnostic imaging tools for diagnosis and the need for surgery for proper administration.
Collapse
Affiliation(s)
- Kesav Sudabattula
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Rajesh Gattani
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Tejaswini Panchagnula
- General Surgery, Sapthagiri Institute of Medical Sciences and Research Centre, Bengaluru, IND
| | - Tushar Dahmiwal
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Nikhil Thatipalli
- General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| | - Bhagyesh Sapkale
- Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND
| |
Collapse
|
8
|
Hilal NA, Rafei A. Adult ileocecal intussusception as an unusual presentation of ascending colon adenocarcinoma: a case report from Sudan. J Surg Case Rep 2024; 2024:rjae337. [PMID: 38812576 PMCID: PMC11132894 DOI: 10.1093/jscr/rjae337] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/12/2023] [Revised: 05/01/2024] [Accepted: 05/06/2024] [Indexed: 05/31/2024] Open
Abstract
Adult colonic intussusception, is a rare entity that is typically associated with underlying organic pathologies, notably colorectal tumors, unlike pediatric cases, which are mostly idiopathic. We present a unique case of a 42-year-old female with ascending colon adenocarcinoma, where ileocecal intussusception served as the initial clinical manifestation. The patient's non-specific symptoms, familial history of colon cancer and subsequent diagnostic evaluations underscore the importance of considering malignancy in such presentations. Successful laparoscopic right hemicolectomy resolved the intussusception. This case, which is the first case to be reported in Sudan, highlights the clinical complexities of adult colonic intussusception, emphasizing the need for a heightened index of suspicion for underlying malignancy and the significance of timely surgical intervention. Furthermore, the challenges encountered in resource-limited settings underscore the necessity for genetic testing to guide familial screenings and identify hereditary factors contributing to colon cancer, providing valuable insights for clinicians managing similar cases.
Collapse
Affiliation(s)
- Nadir Ali Hilal
- Colorectal Surgery, National Center for Gastrointestinal and Liver Diseases, PO Box 12810, Khartoum, Sudan
| | - Ahmed Rafei
- Department of Research, National Center for Gastrointestinal and Liver Diseases, PO Box 12810, Khartoum, Sudan
| |
Collapse
|
9
|
Weiss HZ, Snell A, Knopp BW, Parmar J. An Unusual Presentation of Adult Intussusception. Cureus 2024; 16:e55501. [PMID: 38571868 PMCID: PMC10990272 DOI: 10.7759/cureus.55501] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/03/2024] [Accepted: 03/04/2024] [Indexed: 04/05/2024] Open
Abstract
Intussusception is a condition characterized by the invagination of a proximal segment of the intestine into a distal segment. In adults, intussusception is commonly associated with a lead point. The most alarming lead point is an obstructing malignancy. Here, we present the case of a 57-year-old woman with ileocolic intussusception secondary to colonic adenocarcinoma. The patient presented to the emergency department following an incidental finding of bradycardia, with a heart rate of around 40 beats per minute. She presented with several weeks of cramping, right lower quadrant abdominal pain, lightheadedness, fatigue, and palpitations. A computed tomography scan revealed ileocolic intussusception. After the placement of a semi-permanent right subclavian pacer, the patient underwent a right hemicolectomy. Surgical findings were consistent with ileocolic intussusception suspicious of being initiated by a mass in the right cecum involving the appendiceal orifice and ileocecal valve that invaded through the muscularis propria into subserosal tissue. The mass was resected and sent to pathology, where it was classified as stage II colonic adenocarcinoma. This case highlights a nonspecific presentation of intussusception that was only identified due to incidental bradycardia.
Collapse
Affiliation(s)
- Hannah Z Weiss
- Medical School, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA
| | - Aidan Snell
- Medical School, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA
| | - Brandon W Knopp
- Endocrinology, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA
| | - Jeniel Parmar
- Emergency Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA
| |
Collapse
|
10
|
Masood W, Ahmed R, Fazlani FA, Shakir S, Al Hasibuzzaman M. Multiple intussusceptions secondary to Peutz-Jegher's syndrome in an adult male: a case report from Pakistan. J Surg Case Rep 2024; 2024:rjae008. [PMID: 38304315 PMCID: PMC10832582 DOI: 10.1093/jscr/rjae008] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/15/2023] [Revised: 12/27/2023] [Accepted: 01/05/2024] [Indexed: 02/03/2024] Open
Abstract
Intussusception is a medical condition characterized by invagination of the intestinal segment, causing obstruction and leading to potential complications such as ischemia, necrosis and perforation. While paediatric intussusception is well documented with a peak in ages between 4 and 36 months, adult intussusception is a rare condition usually involving a lead point. In this article, we present an uncommon case of an adult male with worsening of his long-standing lower abdominal pain for the last 2 months. Radiological test reports revealed target-like lesions demonstrating two intestinal intussusceptions, for which he underwent a small bowel anastomosis, exploratory laprotomy and resection. On receiving the histopathology report, hamartomatous polyps with features favouring Peutz-Jegher's syndrome were identified as a possible lead point.
Collapse
Affiliation(s)
- Waniyah Masood
- Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi 75271, Pakistan
| | - Raheel Ahmed
- Department of Surgery, Ruth K. M. Pfau Civil Hospital, Karachi 75271, Pakistan
| | | | - Shaheryar Shakir
- Department of Surgery, Ruth K. M. Pfau Civil Hospital, Karachi 75271, Pakistan
| | - Md Al Hasibuzzaman
- The First Affiliated hospital of Ningbo University, 59 Liuting Jie, Ningbo, 315016, China
- Institute of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh
| |
Collapse
|
11
|
Ballan M, Aghababaei M, Chin AGM, Kim D. A Case of Long-Tract Ileocolic Intussusception Secondary to Well-Differentiated Cecal Adenocarcinoma. Cureus 2024; 16:e52208. [PMID: 38347965 PMCID: PMC10860693 DOI: 10.7759/cureus.52208] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 01/12/2024] [Indexed: 02/15/2024] Open
Abstract
Intussusception denotes the intricate phenomenon wherein one segment of the bowel undergoes invagination or telescoping into its contiguous distal segment. The ensuing invaginated segment may be propelled forward through peristaltic movements, potentially precipitating bowel obstruction or ischemia, culminating in necrosis of the affected bowel segment. Although the precise etiology of intussusception remains elusive, particularly in cases devoid of an identifiable lead point, dysrhythmic contractions and lymphoid hyperplasia have been implicated in the pathophysiology of this condition. We present the case of an 86-year-old African American female with a past medical history of hypertension and asthma who presented to our emergency room with a seven-day history of worsening abdominal. The pain was described as sharp and intermittent, and it would worsen with every meal or drink. A physical exam demonstrated the right lower quadrant with vague abdominal tenderness, especially below the umbilical region. Computed tomography of the abdomen and pelvis revealed a long segment of ileocolic obstructing intussusception in the ascending colon, with a 2.6 cm solid mass serving as a lead point. Swift intervention ensued with an urgent exploratory laparotomy, culminating in a right hemicolectomy to excise the intussuscepted segment of the bowel. The pathological examination identified a well-differentiated adenocarcinoma of the cecum, categorized as T1N0M0, with all 20 resected lymph nodes yielding negative results. This illustrative case presents a unique insight into a patient with ileocolic obstructing intussusception, caused by a well-differentiated adenocarcinoma acting as the lead point, a relatively uncommon occurrence in adults. Diagnosing intussusception in adults is challenging due to its nonspecific symptoms, which are similar to those of various other gastrointestinal disorders. Therefore, it is crucial for medical providers to be acutely aware of the possibility that adenocarcinoma can trigger obstructing intussusception in various parts of the bowel.
Collapse
Affiliation(s)
- Mohamad Ballan
- Surgery, William Carey University College of Osteopathic Medicine, Hattiesburg, USA
| | - Mahroo Aghababaei
- Surgery, William Carey University College of Osteopathic Medicine, Hattiesburg, USA
| | | | - Dmitriy Kim
- Surgery, St. John's Episcopal Hospital, Queens, USA
| |
Collapse
|
12
|
Ali MOM, Mohamed NIA, Ahmed AAE, Basher MOS, Mohamed SAA, Elgemaabi OM. Intussusception revealing right colonic adenocarcinoma in a 61-year-old woman: a case report. J Med Case Rep 2023; 17:299. [PMID: 37443097 DOI: 10.1186/s13256-023-04027-4] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/25/2022] [Accepted: 06/06/2023] [Indexed: 07/15/2023] Open
Abstract
INTRODUCTION Adult Intussusception is an uncommon diagnosis, with one to three cases occurring in a population of 1,000,000 per year, primarily due to underlying pathological lead points, of which 70% are malignant. Lipoma is the most common benign tumour, and primary adenocarcinoma is the most common malignant one. Early diagnosis and treatment are essential to reducing poor outcomes, including ischemia, perforation, and sepsis. Computed tomography imaging is a modality of choice for diagnosis. With a diagnostic accuracy of up to 100% and a specificity of up to 71%. Surgical intervention is the definitive treatment, and the decision is taken according to the situation. CASE PRESENTATION A 61-year-old Black African female presented to our surgical casualty with intermittent colicky abdominal pain for 1 month. After that, she started to experience abdominal swelling in the right iliac fossa. A CT scan confirmed the presence of colo-colic Intussusception, cecum-ascending-transverse colon. Laparotomy was scheduled, and a right hemicolectomy was done accordingly. Diagnosis of adenocarcinoma (Dukes stage B2) was made histologically. CONCLUSION Intussusception in adults is a challenging diagnosis requiring high clinical suspicion and has a high incidence of fatal complications. Colonic cancer can be worsening by any infection and chronic medical problem. CT imaging is the lifesaving modality of choice for diagnosis. Good patient outcomes depend on timely diagnosis and recruitment of a multi-disciplinary team.
Collapse
|
13
|
Gosai F, Espejo K, Zussman R, DeMartini S, Wilfong C. A Rare Case of Spontaneous Intussusception in an Elderly Patient. Cureus 2023; 15:e40726. [PMID: 37485156 PMCID: PMC10360450 DOI: 10.7759/cureus.40726] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 06/20/2023] [Indexed: 07/25/2023] Open
Abstract
Intussusception is an uncommon pathology in the adult population. Most intussusception cases result from an underlying pathological lead point, oftentimes a malignant neoplasm. We report a case of intussusception in an adult male patient who presented with abdominal pain and currant jelly diarrhea. The patient underwent laparoscopic right hemicolectomy and the biopsy of the affected colon did not show any pathological lead point. Intussusception remains an important differential diagnosis in patients presenting with abdominal pain and bloody diarrhea.
Collapse
Affiliation(s)
- Falgun Gosai
- Hospitalist, Saint Francis Medical Center, Peoria, USA
| | - Kyle Espejo
- Medicine, University of Illinois College of Medicine Peoria, Peoria, USA
| | - Rachel Zussman
- Medicine, University of Illinois College of Medicine Peoria, Peoria, USA
| | - Stephen DeMartini
- Medicine, University of Illinois College of Medicine Peoria, Peoria, USA
| | | |
Collapse
|
14
|
Tempel DG, Balk DS, Schafer JM, Hoffmann B. A brief review of diagnostic properties of point-of-care ultrasound for adult bowel intussusception: Making the case for ultrasound. J Ultrason 2023; 23:e90-e96. [PMID: 37520744 PMCID: PMC10379853 DOI: 10.15557/jou.2023.0016] [Citation(s) in RCA: 3] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/06/2022] [Accepted: 01/30/2023] [Indexed: 08/01/2023] Open
Abstract
Undifferentiated abdominal pain in adults is a common chief complaint in acute care clinics and emergency departments worldwide, representing up to 10% of visits to emergency departments. Many patients have a non-specific presentation and an initial workup with labwork, urine analysis or X-ray might not reveal a specific diagnosis. Although bowel intussusception is a primarily pediatric disease, adult intussusception is a recognized but rare cause of bowel obstruction often requiring surgical intervention. However, recent data from advanced multi-detector computed tomography imaging shows that milder or recurring cases in adults have been underrecognized. Multi-detector computed tomography is still the imaging gold standard for detecting intussusception in adults, but new data showed that sonographers with basic training using the point-of-care ultrasound approach have a reasonable accuracy in detecting this pathology. As the point-of-care ultrasound for undifferentiated abdominal pain is an emerging core skill in the acute care setting, knowledge of sonographic signs of intestinal intussusception should be included in the skill set of physicians. Sonographic findings in adults mimic pediatric cases, but different location patterns and higher malignancy rates exist in adults. In this manuscript, we will review the current literature on adult intussusception and summarize key knowledge of intestinal intussusception in adults. We will present four adult patients diagnosed with different types of adult acute bowel intussusception using the point-of-care ultrasound and describe a focused scanning approach with typical sonographic findings.
Collapse
Affiliation(s)
- David G. Tempel
- Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
| | - Daniel S. Balk
- Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
| | - Jesse M. Schafer
- Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
| | - Beatrice Hoffmann
- Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
| |
Collapse
|
15
|
González-Carreró Sixto C, Baleato-González S, García Palacios JD, Sánchez Bernal S, Junquera Olay S, Bravo González M, García Figueiras R. Intestinal intussusception in adults: Location, causes, symptoms, and therapeutic management. RADIOLOGIA 2023; 65:213-221. [PMID: 37268363 DOI: 10.1016/j.rxeng.2022.10.005] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/02/2020] [Accepted: 06/30/2021] [Indexed: 06/04/2023]
Abstract
OBJECTIVE Intestinal intussusception is difficult to diagnose in adults because the symptoms are nonspecific. However, most have structural causes that require surgical treatment. This paper reviews the epidemiologic characteristics, imaging findings, and therapeutic management of intussusception in adults. MATERIALS AND METHODS This retrospective study identified patients diagnosed with intestinal intussusception who required admission to our hospital between 2016 and 2020. Of the 73 cases identified, 6 were excluded due to coding errors and 46 were excluded because the patients were aged <16 years. Thus, 21 cases in adults (mean age, 57 years) were analyzed. RESULTS The most common clinical manifestation was abdominal pain, reported in 8 (38%) cases. In CT studies, the target sign yielded 100% sensitivity. The most common site of intussusception was the ileocecal region, reported in 8 (38%) patients. A structural cause was identified in 18 (85.7%) patients, and 17 (81%) patients required surgery. The pathology findings were concordant with the CT findings in 94.1% of cases; tumours were the most frequent cause (6 (35.3%) benign and 9 (64.7%) malignant). CONCLUSIONS CT is the first-choice test for the diagnosis of intussusception and plays a crucial role in determining its aetiology and therapeutic management.
Collapse
Affiliation(s)
| | - S Baleato-González
- Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
| | | | - S Sánchez Bernal
- Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
| | - S Junquera Olay
- Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
| | - M Bravo González
- Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
| | - R García Figueiras
- Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
| |
Collapse
|
16
|
Ahdi HS, Kruchko D, Asado N, Kakodkar S. A Case of Jejuno-Jejunal Intussusception Caused by Underlying Metastatic Melanoma. Cureus 2023; 15:e36217. [PMID: 37065309 PMCID: PMC10103802 DOI: 10.7759/cureus.36217] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 03/15/2023] [Indexed: 03/18/2023] Open
Abstract
Intussusception in adults is a rare finding with a majority of cases occurring in the pediatric population. It occurs infrequently and its presentation, etiology, and treatment differ from childhood intussusception. When discovered in adults, it raises suspicion for a neoplastic process serving as the pathological lead point. Cross-sectional imaging is the primary study of choice for diagnosis, but at times, a more invasive approach involving an exploratory laparotomy is required posing an increased risk for morbidity and mortality. Here we present a 64-year-old male who was found to have jejunal-jejunal intussusception that was surgically removed with pathology revealing metastatic melanoma as the lead point. This case highlights a unique presentation of a melanoma that was previously eradicated with immunotherapy and now had metastasized to the intestine many years later.
Collapse
Affiliation(s)
- Hardeep S Ahdi
- Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA
| | - David Kruchko
- Gastroenterology and Hepatology, Advocate Lutheran General Hospital, Park Ridge, USA
| | - Nahren Asado
- Pathology, Advocate Lutheran General Hospital, Park Ridge, USA
| | - Samir Kakodkar
- Department of Medicine, Division of Gastroenterology, Advocate Lutheran General Hospital, Park Ridge, USA
| |
Collapse
|
17
|
Haidaran I, Haidaran AI. Adult intussusception: A case report. Int J Surg Case Rep 2023; 105:107977. [PMID: 36989624 PMCID: PMC10074585 DOI: 10.1016/j.ijscr.2023.107977] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/29/2022] [Revised: 03/01/2023] [Accepted: 03/11/2023] [Indexed: 03/17/2023] Open
Abstract
INTRODUCTION Intussusception is a recognised cause of bowel obstruction and is significantly more common in paediatric patients. Adult intussusception is rare and requires a predisposing factor in the vast majority of patients and this may include a benign lesion, a malignant lesion or bowel wall abnormality such as inflammatory bowel disease. PRESENTATION OF CASE We present the case of a patient presenting with upper abdominal pain, nausea, vomiting and weakness. The patient had ongoing mild intermittent abdominal pain for months which was investigated with an oesophagogastroduodenoscopy (OGD) that showed gastritis. There were features of peritonism on clinical examination and this was associated with raised inflammatory markers. A Computed Tomography (CT) scan showed telescoping of the ileum with proximal bowel distension suggesting bowel obstruction. The patient underwent emergency surgical resection. Histopathology assessment did not identify a causative factor for the intussusception. DISCUSSION We present a case of idiopathic entero-enteric intussusception in an adult which is not commonly seen. Clinical history of chronic intermittent abdominal pain and CT abdomen are helpful in establishing the diagnosis. Despite that conservative approach is described in the literature, surgery continues to be the only option in patients who are unstable and show signs of peritonitis. CONCLUSION Adult intussusception is not a common condition and can be difficult to diagnose. Patients with intussusception may report a relatively long period of intermittent abdominal pain that worsen acutely due to complete obstruction. CT is the most useful investigative modality to confirm the diagnosis of intussusception.
Collapse
|
18
|
Muacevic A, Adler JR. Transient Colonic Intussusception Versus Colon Adenocarcinoma: A Case Report on Ultrasound Features in the Emergency Department. Cureus 2022; 14:e30710. [PMID: 36320791 PMCID: PMC9606179 DOI: 10.7759/cureus.30710] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 10/26/2022] [Indexed: 12/02/2022] Open
Abstract
Intussusception in adults is a rare pathology due to the telescoping of a bowel segment into a section adjacent to it. Almost all cases are linked to a pathological lead point, which is often a colorectal carcinoma where the intussusception involves the large intestine. Likely to occur in the same clinical setting, the differential diagnosis between intussusception and colon carcinoma by ultrasound in the emergency department can be quite challenging. We present a rare case of transient colonic intussusception with a well-differentiated colon adenocarcinoma as the lead point in a 43-year-old patient. The point of care ultrasound (POCUS) revealed the target sign characteristic of intussusception at the level of maximum pain, associated with a pseudokidney sign. However, the pseudokidney sign was indeed an adenocarcinoma of the ascending colon visualized by colonoscopy and per op.
Collapse
|
19
|
Seth NH, Kulkarni CA, Patil S, Wadhokar OC. Postoperative Physiotherapy Approach for a Rare Case of Adult Ileocecal Intussusception. Cureus 2022; 14:e29668. [DOI: 10.7759/cureus.29668] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/13/2022] [Accepted: 09/27/2022] [Indexed: 11/05/2022] Open
|
20
|
Hejazi P, Yousefi S, Hemmati H, Faraji N, Mohammadyari F. Intussusception of the bowel in a young woman: A case report. Clin Case Rep 2022; 10:e6309. [PMID: 36177073 PMCID: PMC9478627 DOI: 10.1002/ccr3.6309] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/26/2022] [Revised: 07/11/2022] [Accepted: 08/25/2022] [Indexed: 12/05/2022] Open
Abstract
Intussusception is a condition in which a segment of the gastrointestinal tract invaginates into the lumen of another segment. Adult intussusception is less common than juvenile intussusception in terms of cause, appearance, and treatment. Because the clinical picture can be quite atypical and difficult to interpret, it is frequently misdiagnosed at first. Herein, we report the case of a previously healthy 23-year-old female patient who presented to the Emergency Department (ED) with acute abdominal pain, vomiting, and diarrhea for 1 day following her last menstrual period. Ileocecal intussusception was discovered throughout the investigation. She was rushed for open abdominal surgery. Meckel's diverticulum was found as a pathologic lead point in the resected specimen, with no evidence of malignancy. Although intussusception is rare in adults, it should be considered in patients who have nonspecific stomach pain.
Collapse
Affiliation(s)
- Peyman Hejazi
- Razi Clinical Research Development Unit, Razi HospitalGuilan University of MedicalRashtIran
| | - Saeed Yousefi
- Department of General Surgery, School of Medicine Road Trauma Research Center, Razi HospitalGuilan University of Medical SciencesRashtIran
| | - Hossein Hemmati
- Razi Clinical Research Development Unit, Razi HospitalGuilan University of MedicalRashtIran
- Department of General Surgery, School of Medicine Road Trauma Research Center, Razi HospitalGuilan University of Medical SciencesRashtIran
| | - Niloofar Faraji
- Razi Clinical Research Development Unit, Razi HospitalGuilan University of MedicalRashtIran
| | | |
Collapse
|
21
|
Abed V, Faber A, Jageka C, Goleniak R, Fadel R. Intussusception in the Setting of an Ulcerative Colitis Flare. Case Rep Gastrointest Med 2022; 2022:3559464. [PMID: 35677833 PMCID: PMC9170386 DOI: 10.1155/2022/3559464] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/18/2022] [Accepted: 05/19/2022] [Indexed: 11/17/2022] Open
Abstract
Intussusception is an extraordinary cause of acute abdomen in adults and has been defined as the telescoping of a bowel segment into the lumen of an adjacent segment. A 43-year-old female presented to our hospital's emergency department (ED) with 10+ episodes of bloody diarrhea per day, left-sided abdominal pain, and the inability to tolerate oral intake for one month. She was initially diagnosed with ulcerative colitis (UC) ten years ago and is currently on mesalamine oral and enema therapy. She presented to our gastroenterology clinic two weeks after the beginning of her flare and was started on prednisone 40 mg daily. This did not improve her symptoms, and she presented to the ED two weeks later. She underwent a computed tomography (CT) abdomen/pelvis which revealed intussusception in the left hemiabdomen with no definite lead point measuring 5.6 cm in the craniocaudal dimension with pneumatosis and no evidence of bowel obstruction. There were no other significant laboratory abnormalities. Acute care surgery was consulted and suggested obtaining a CT enterography for further evaluation which showed spontaneous resolution of intussusception with no evidence of pneumatosis, portal venous gas, or intraperitoneal free air. She reports that following oral contrast intake, she "felt movement and relaxation" in her abdomen with substantial pain relief. Infectious workup was negative, and therapy was initiated with intravenous steroids. In conclusion, intussusception has been very rarely reported in patients with UC with the most common treatment being surgical resection. However, conservative management in the absence of bowel obstruction can be attempted.
Collapse
Affiliation(s)
- Varag Abed
- Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
| | - Alexis Faber
- Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
| | - Cristina Jageka
- Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
| | - Ryan Goleniak
- Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
| | - Raef Fadel
- Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
| |
Collapse
|
22
|
Boucher B, Fleites O, Varghese R, Myuran Nagaratnam J, Yabit F, Jorge J. Intussusception in the Geriatric Population: A Case Report. Cureus 2022; 14:e24663. [PMID: 35663708 PMCID: PMC9156398 DOI: 10.7759/cureus.24663] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 05/02/2022] [Indexed: 11/05/2022] Open
|
23
|
Poudel D, Lamichhane SR, Ajay K, Maharjan N. Colocolic intussusception secondary to colonic adenocarcinoma with impending caecal perforation in an elderly patient: A rare case report. Int J Surg Case Rep 2022; 94:107093. [PMID: 35461183 PMCID: PMC9046794 DOI: 10.1016/j.ijscr.2022.107093] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/14/2022] [Revised: 04/13/2022] [Accepted: 04/13/2022] [Indexed: 11/17/2022] Open
Abstract
Introduction Intussusception is a surgical emergency in which a part of the intestine slides into the distal adjacent part. Adult colocolic intussusception secondary to a tumoral process is a rare but serious clinical condition requiring immediate surgical intervention. Case presentation We report a case of a 65-year-old male patient presenting with abdominal pain and distention, subsequently diagnosed with colocolic intussusception in the descending colon with closed-loop bowel obstruction with impending caecal perforation. An exophytic mass on the descending colon was discovered intra-operatively, prompting a subtotal colectomy with ileosigmoidal anastomosis and loop ileostomy with the suspicion of malignancy. The histopathological examination of the surgical specimen concluded a moderately-differentiated colonic adenocarcinoma with 40% mucinous component. Clinical discussion Adult intestinal intussusception is a rare but serious condition differing greatly in etiology from its pediatric counterpart. Its preoperative diagnosis is challenging in adults, which appears to be due to its imprecise presenting signs and symptoms; thus, the condition can be mistaken for other causes of intestinal obstruction. Adenocarcinomas remain the most common cause of malignant tumors in the colon, which also makes them one of the causes for colocolic intussusception. Conclusion Intussusception can appear as a surgical emergency even in the elderly, necessitating prompt surgical intervention to avoid intestinal ischemia and gangrene. Its diagnosis can be aided to a great degree by CT imaging.
Colocolic intussusception is a rare surgical emergency in adults and is often associated with neoplastic lead points. Clinical diagnosis of the disease is challenging because of its non-specific presenting features. However, its diagnosis can be aided to a great degree by CT imaging. The disease necessitates prompt surgical intervention to avoid intestinal ischemia and gangrene.
Collapse
|
24
|
Lazenby C, Nielson JA, Perry RS. A Case Report on Gastric Remnant Intussusception. Cureus 2022; 14:e21320. [PMID: 35186579 PMCID: PMC8848636 DOI: 10.7759/cureus.21320] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 01/17/2022] [Indexed: 11/06/2022] Open
Abstract
We present a case of intussusception of a gastric remnant in a patient years after undergoing a Billroth II procedure that was treated with esophagogastroduodenoscopy. Although rare in adults, intussusception has been documented with increasing frequency in adult patients who have undergone Billroth II, mini-gastric bypass, and Roux-en-Y gastric bypass surgery. Timely management can decrease damage due to ischemia.
Collapse
|
25
|
Sena RC, Forosisky G. Adult Idiopathic Ileocolonic Intussusception: A Case Report. Cureus 2021; 13:e20393. [PMID: 35036223 PMCID: PMC8752403 DOI: 10.7759/cureus.20393] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 12/13/2021] [Indexed: 11/05/2022] Open
Abstract
Abdominal pain is a common chief complaint seen in the emergency department (ED), both in adult and pediatric populations. In pediatric emergency medicine, one diagnosis that is often considered is intussusception; in adult emergency medicine, this is typically less common. The classic teaching in adults is that the most common cause of intussusception is malignancy. In the following case report, however, the etiology of intussusception was not from malignancy but rather idiopathic. This case report describes an elderly female presenting to the ED for abdominal pain, nausea, vomiting, and hematochezia. She underwent abdominal imaging with findings concerning for intussusception; this necessitated urgent operative intervention. She was found to have ileocolonic intussusception. Tissue biopsy was sent for analysis to evaluate for malignancy. This was negative. While emergency physicians often keep intussusception high on their list of differential diagnoses when dealing with pediatric patients with abdominal pain, it is rarely considered in the adult population. Abdominal pain is one of the most common chief complaints seen in emergency medicine. Intussusception should definitely be considered as this could be the etiology of abdominal pain and, in rare circumstances, the potential etiology for an acute abdomen.
Collapse
|
26
|
Xia F, Sun Z, Wu JH, Zou Y. Intussusception after reconstruction following gastrectomy for gastric cancer. World J Surg Oncol 2021; 19:340. [PMID: 34876149 PMCID: PMC8653605 DOI: 10.1186/s12957-021-02456-3] [Citation(s) in RCA: 8] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/31/2021] [Accepted: 11/24/2021] [Indexed: 02/02/2023] Open
Abstract
Background Gastric cancer is the most prevalent tumor in Chinese men, and surgery is currently the most important treatment. Billroth II and Roux-en-Y are the anastomosis methods used for reconstruction after gastrectomy. Jejunal intussusception is a rare complication after gastric surgery. Main Body Intussusception after gastric surgery occurs mostly at the gastrojejunostomy site for Billroth II reconstruction, and the Y-anastomosis site for Roux-en-Y reconstruction. Many studies have reported that postoperative intussusception appears at the anastomosis after bariatric surgery, while a few have reported intussusception at the anastomosis and its distal end after radical gastrectomy. Conclusion A review was carried out to analyze intussusception after radical gastrectomy with roux-en-y anastomosis during the current situation. And the relevant mechanisms, diagnosis, treatment methods, etc. are described, hoping to provide better guidance for clinicians
Collapse
Affiliation(s)
- Feng Xia
- Hepatic Surgery Center, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China
| | - Zhen Sun
- Gastrointestinal Surgery Center, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, 1095, Jiefang Avenue, Wuhan, Hubei, China
| | - Jian-Hong Wu
- Gastrointestinal Surgery Center, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, 1095, Jiefang Avenue, Wuhan, Hubei, China
| | - You Zou
- Gastrointestinal Surgery Center, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, 1095, Jiefang Avenue, Wuhan, Hubei, China.
| |
Collapse
|
27
|
Fontana F, Piacentino F, Ossola C, Pascarella RD, Franchi C, Curti M, Coppola A, Basile A, Saverio SD, Carcano G, Venturini M. Gangliocytic paraganglioma leading to duodeno-jejunal intussusception: A case report. Radiol Case Rep 2021; 16:3977-3981. [PMID: 34729128 PMCID: PMC8545659 DOI: 10.1016/j.radcr.2021.09.056] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/05/2021] [Revised: 09/19/2021] [Accepted: 09/20/2021] [Indexed: 02/07/2023] Open
Abstract
The intussusception of the small bowel is rarely encountered in adult patients and is frequently associated with a lead point that is often malignant. In a 69-year-old female patient with an episode of gastrointestinal (GI) bleeding, computed tomography (CT) showed a duodenal-jejunal intussusception caused by an intraluminal mass. Open polypectomy and reduction of intussusception were performed and the diagnosis of gangliocytic paraganglioma was made at pathological evaluation. It would be important to consider neoplasms like gangliocytic paraganglioma in the setting of adult small bowel intussusception.
Collapse
Affiliation(s)
- Federico Fontana
- Diagnostic and Interventional Radiology Department, Ospedale di Circolo, ASST dei Sette Laghi, Varese 21100, Italy
- School of Medicine and Surgery, Università degli Studi dell'Insubria, Varese 21100, Italy
| | - Filippo Piacentino
- Diagnostic and Interventional Radiology Department, Ospedale di Circolo, ASST dei Sette Laghi, Varese 21100, Italy
| | - Christian Ossola
- School of Medicine and Surgery, Università degli Studi dell'Insubria, Varese 21100, Italy
| | | | - Caterina Franchi
- School of Medicine and Surgery, Università degli Studi dell'Insubria, Varese 21100, Italy
| | - Marco Curti
- School of Medicine and Surgery, Università degli Studi dell'Insubria, Varese 21100, Italy
| | - Andrea Coppola
- Diagnostic and Interventional Radiology Department, Ospedale di Circolo, ASST dei Sette Laghi, Varese 21100, Italy
| | - Antonio Basile
- Department of Medical and Surgical Sciences and Advanced Technologies, Radiodiagnostic and Radiotherapy Unit, University Hospital "Policlinico-Vittorio Emanuele", Catania 95123, Italy
| | - Salomone Di Saverio
- School of Medicine and Surgery, Università degli Studi dell'Insubria, Varese 21100, Italy
- Department of General Surgery, ASUR Marche, AV5, Hospital of San Benedetto del Tronto, San Benedetto del Tronto 63074, Italy
| | - Giulio Carcano
- School of Medicine and Surgery, Università degli Studi dell'Insubria, Varese 21100, Italy
- Surgery Department, Ospedale di Circolo, ASST dei Sette Laghi, Varese 21100, Italy
| | - Massimo Venturini
- Diagnostic and Interventional Radiology Department, Ospedale di Circolo, ASST dei Sette Laghi, Varese 21100, Italy
- School of Medicine and Surgery, Università degli Studi dell'Insubria, Varese 21100, Italy
| |
Collapse
|
28
|
Jadhav KP, Krishnan G. Triple Intussusception in an Adult-A Rare Presentation of Adenocarcinoma Ileum. Surg J (N Y) 2021; 7:e271-e274. [PMID: 34632062 PMCID: PMC8492135 DOI: 10.1055/s-0041-1733834] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/27/2021] [Accepted: 06/16/2021] [Indexed: 11/03/2022] Open
Abstract
Intestinal intussusception is uncommon in adults. It occurs more often in the small intestine than in the colon. In adults, when small bowel intussusception occurs, it can be due to a malignant lead point. Malignant etiology is most frequently due to diffuse metastatic disease. We present a rare case of an 18-year-old woman who was diagnosed with jejunojejunal, jejunoileal, and colocolic intussusceptions. She presented with vomiting, abdominal pain, and passage of semisolid stools for 5 days. During emergency exploratory laparotomy, multiple polyps were found in the jejunum, ileum, and sigmoid. Jejunotomy and sigmoidotomy were done to remove the respective polyps. The ileal polyp showed hemorrhagic changes; hence, an intraoperative decision was taken to proceed with resection and anastomosis. On histopathological examination, the resected ileal part showed moderately differentiated adenocarcinoma (grade 2) arising from an adenomatous polyp, while the jejunal polyp and sigmoid polyp were adenomatous polyps with low-grade dysplasia. Patient received six cycles of adjuvant chemotherapy consisting of capecitabine and oxaliplatin (CAPEOX regimen). After 2 years, she is symptom free with a normal colonoscopy. The treatment of intussusception in adults typically involves surgery, often with bowel resection as there is always a pathologic leading cause which may be malignant, like in our case.
Collapse
Affiliation(s)
- Kirankumar P Jadhav
- Department of Surgery, B. J. Government Medical College and Sassoon General Hospital, Pune, Maharashtra, India
| | - Gayathri Krishnan
- Department of Surgery, B. J. Government Medical College and Sassoon General Hospital, Pune, Maharashtra, India
| |
Collapse
|
29
|
Silva V, Khalil K, Zaidi SR, Highsmith S, Tucker JI. Intussusception and Chronic Marijuana Use in a Young Adult. AMERICAN JOURNAL OF CASE REPORTS 2021; 22:e932479. [PMID: 34388145 PMCID: PMC8370136 DOI: 10.12659/ajcr.932479] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/16/2022]
Abstract
Patient: Female, 26-year-old
Final Diagnosis: Intussusception
Symptoms: Abdominal pain • nausea
Medication: —
Clinical Procedure: CT scan • surgery
Specialty: Gastroenterology and Hepatology • General and Internal Medicine • Surgery
Collapse
Affiliation(s)
- Vixey Silva
- Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA
| | - Krystina Khalil
- Department of Internal Medicine, St. Mary Mercy Hospital, Livonia, MI, USA
| | - Syeda Ramsha Zaidi
- Department of Internal Medicine, St. Mary Mercy Hospital, Livonia, MI, USA
| | - Shanequa Highsmith
- Department of Internal Medicine, St. Mary Mercy Hospital, Livonia, MI, USA
| | - Jared I Tucker
- Department of Internal Medicine, St. Mary Mercy Hospital, Livonia, MI, USA
| |
Collapse
|
30
|
Reddy KM, Maduke T, Wade F, Hachem C. Primary jejunal amelanotic melanoma: case report and review of literature. Clin J Gastroenterol 2021; 14:1376-1380. [PMID: 34081261 DOI: 10.1007/s12328-021-01446-y] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/09/2021] [Accepted: 05/17/2021] [Indexed: 02/07/2023]
Abstract
Intussusception more commonly occurs in pediatrics but is a rare cause of bowel obstruction and gastrointestinal bleeding in adults. It typically occurs in adults due to a malignancy, which serves as a pathologic lead point. We present a case of a 64-year-old female with nausea, vomiting, and melena who was found to have intussusception associated with a primary jejunal amelanotic melanoma. Both intussusception and primary small bowel melanomas are rare causes of obstruction and bleeding. Intussusception occurring as a result of a primary small bowel amelanotic melanoma is exceedingly rare with very few reported cases. We provide a case report and review of the literature.
Collapse
Affiliation(s)
- Kavya M Reddy
- Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, 2780 Skypark Dr., St 125, Los Angeles, CA, 90505, USA.
| | - Tinashe Maduke
- Division of Pulmonary and Critical Care, University of Missouri School of Medicine, 1 Hospital Drive, Columbia, MO, 65212, USA
| | - Francis Wade
- Department of Internal Medicine, Saint Louis University School of Medicine, 1008 South Spring Ave, Saint Louis, MO, 63110, USA
| | - Christine Hachem
- Department of Internal Medicine, Saint Louis University School of Medicine, 1008 South Spring Ave, Saint Louis, MO, 63110, USA.,Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, 1008 South Spring Ave, Saint Louis, MO, 63110, USA
| |
Collapse
|
31
|
Panzera F, Di Venere B, Rizzi M, Biscaglia A, Praticò CA, Nasti G, Mardighian A, Nunes TF, Inchingolo R. Bowel intussusception in adult: Prevalence, diagnostic tools and therapy. World J Methodol 2021; 11:81-87. [PMID: 34026581 PMCID: PMC8127421 DOI: 10.5662/wjm.v11.i3.81] [Citation(s) in RCA: 29] [Impact Index Per Article: 7.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/18/2021] [Revised: 02/15/2021] [Accepted: 03/18/2021] [Indexed: 02/06/2023] Open
Abstract
Intussusception is defined as invagination of one segment of the bowel into an immediately adjacent segment. The intussusception refers to the proximal segment that invaginates into the distal segment, or the intussusception (recipient segment). Intussusception, more common occur in the small bowel and rarely involve only the large bowel. In direct contrast to pediatric etiologies, adult intussusception is associated with an identifiable cause in almost all the symptomatic cases while the idiopathic causes are extremely rare. As there are many common causes of acute abdomen, intussusception should be considered when more frequent etiologies have been ruled out. In this review, we discuss the symptoms, location, etiology, characteristics, diagnostic methods and treatment strategies of this rare and enigmatic clinical entity in adult.
Collapse
Affiliation(s)
- Francesco Panzera
- Department of Endoscopy, "Madonna delle Grazie" Hospital, Matera 75100, Italy
| | - Beatrice Di Venere
- Department of Surgery, "Madonna delle Grazie" Hospital, Matera 75100, Italy
| | - Marina Rizzi
- Department of Endoscopy, "Madonna delle Grazie" Hospital, Matera 75100, Italy
| | - Assunta Biscaglia
- Department of Radiology, "Madonna delle Grazie" Hospital, Matera 75100, Italy
| | | | - Gennaro Nasti
- Department of Surgery, "Madonna delle Grazie" Hospital, Matera 75100, Italy
| | - Andrea Mardighian
- Interventional Radiology Unit, "F. Miulli" General Regional Hospital, Acquaviva delle Fonti 70021, Bari, Italy
| | - Thiago Franchi Nunes
- Department of Radiology, Santa Casa de Campo Grande, Campo Grande 79010-050, Brazil
| | - Riccardo Inchingolo
- Interventional Radiology Unit, "F. Miulli" General Regional Hospital, Acquaviva delle Fonti 70021, Bari, Italy
| |
Collapse
|
32
|
Romano M, Tartaglia E, Amodio F, Gragnaniello A, Bortone S, Fabozzi M. Treatment of postoperative jejunal intussusception in adult with oral gastrografin after laparoscopic low rectal resection. A case report. Int J Surg Case Rep 2020; 74:120-123. [PMID: 32836205 PMCID: PMC7452584 DOI: 10.1016/j.ijscr.2020.08.005] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/15/2020] [Revised: 07/25/2020] [Accepted: 08/01/2020] [Indexed: 12/13/2022] Open
Abstract
INTRODUCTION Postoperative intussusception is a rare cause of intestinal obstruction in adults. Intussusception refers to a condition in which a segment of the intestine invaginates into the lumen of an adjacent segment of the intestine. PRESENTATION OF CASE We report a case of postoperative jejunojejunal intussusception in a 42-year-old male following a laparoscopic low anterior resection for rectal cancer. In post-operative day (POD) 2 the patient showed intermittent bowel obstruction and fever. Diagnosis was established with abdominal computed tomography (CT) and enteroclysis, which led to a spontaneous reduction of the invagination. DISCUSSION The incidence of intussusception in adults is rare condition. It represents less than 5% of all cases. In adults, transient asymptomatic enteric intussusception often resolves spontaneously without any treatment. When bowel obstruction is complete and persistent, surgery is need. Intussusception as cause of intestinal obstruction should be kept in mind in a post operative patient who develops obstructive symptoms. Early diagnosis makes the difference between surgical and others treatment. The pathogenesis and diagnosis of postoperative intussusception in the adult is discussed in the case report. CONCLUSION The authors presented a rare cause of postoperative small bowel obstruction treated without surgery. The peculiarity of this case report is that the authors have successfully used, in an adult, conservative treatment with gastrografin, which is the treatment of choice used in children. The use of gastrografin was decisive and there were no recurrences in the follow up.
Collapse
Affiliation(s)
- Mafalda Romano
- Department of General and Oncological Surgery, Hospital "A.Tortora", Pagani, Italy.
| | - Ernesto Tartaglia
- Department of Laparoscopic and Robotic General Surgery, Azienda Ospedaliera dei Colli "Monaldi Hospital", Naples, Italy
| | - Ferdinando Amodio
- Department of General and Oncological Surgery, Hospital "A.Tortora", Pagani, Italy
| | - Angelo Gragnaniello
- Department of General and Oncological Surgery, Hospital "A.Tortora", Pagani, Italy
| | - Sara Bortone
- Department of Radiology, Hospital "A.Tortora", Pagani, Italy
| | - Massimiliano Fabozzi
- Department of General and Oncological Surgery, Hospital "A.Tortora", Pagani, Italy
| |
Collapse
|
33
|
Abstract
Retrograde intussusception (RI), although relatively uncommon, has been increasingly seen in adults post Roux-en-Y gastric bypass (RYGB) surgery. The exact mechanism for its occurrence remains unknown but several theories have attributed it to bowel persialtic dysmotility. The increase in bariatric surgery over the last decade has resulted in a proportionate increase in the number of cases of intussusception seen globally. We report a case of RI seven years following RYGB done for morbid obesity.
Collapse
Affiliation(s)
- Akshay Kumar
- Cardiothoracic Surgery, Lokmanya Tilak Municipal Medical College & General Hospital, Mumbai, IND
| | - Stephanie Ogbonda
- Surgery, University of Texas Health Science Center at Houston, Houston, USA
| | - Purnadeo Persaud
- Surgery, Kansas City University of Medicine and Biosciences, Kansas City, USA
| | - Nimisha Shiwalkar
- Anesthesiology, Lokmanya Tilak Municipal Medical College & General Hospital, Mumbai, IND
| |
Collapse
|
34
|
Adult Ileocolic Intussusception from the Appendix. Case Rep Emerg Med 2019; 2019:3272618. [PMID: 31885942 PMCID: PMC6925803 DOI: 10.1155/2019/3272618] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/05/2019] [Accepted: 10/26/2019] [Indexed: 11/20/2022] Open
Abstract
Intussusception is more commonly considered in the pediatric patient with abdominal pain, but can occur in adults as well. Adult patients are more likely to have an underlying intra-abdominal pathology leading to the condition. We present an adult patient presenting with abdominal pain with ileocecal intussusception diagnosed on imaging and confirmed surgically. In this case, appendiceal pathology served as the lead point for the intussusception.
Collapse
|
35
|
Zhornitskiy A, Le L, Tareen S, Abdullahi G, Karunasiri D, Tabibian JH. Gastro-gastric intussusception in the setting of a neuroendocrine tumor: A case report. World J Clin Cases 2019. [DOI: 10.12998/wjcc.v7.i21.3500] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/04/2023] Open
|
36
|
Zhornitskiy A, Le L, Tareen S, Abdullahi G, Karunasiri D, Tabibian JH. Gastro-gastric intussusception in the setting of a neuroendocrine tumor: A case report. World J Clin Cases 2019; 7:3517-3523. [PMID: 31750333 PMCID: PMC6854402 DOI: 10.12998/wjcc.v7.i21.3517] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/20/2019] [Revised: 08/23/2019] [Accepted: 10/05/2019] [Indexed: 02/05/2023] Open
Abstract
BACKGROUND While in children intussusception is often idiopathic, in adults it is commonly caused by a pathologic condition functioning as a lead point. It is important to note that a variety of pathologic conditions may trigger intussusception, with malignancy being a relatively frequent culprit in adults; this should be considered high on the differential diagnosis during evaluation. CASE SUMMARY This is a case of a 40-year-old female presenting to the emergency department (ED) with three days of acute on chronic, peri-umbilical abdominal pain described as waxing and waning, and pressure-like in nature. Initial computed tomography (CT) of the abdomen and pelvis with contrast in the ED (after her pain had resolved) re-demonstrated a previously noted 13 mm lesion in the gastric antrum but no clear cause of the pain. Endoscopic ultrasound was pursued, and the mass lesion was sampled via fine needle biopsy. Post-procedure the patient experienced another episode of severe pain which prompted a repeat stat CT abdomen and pelvis with contrast; this re-demonstrated the 13 mm antral lesion and in addition was remarkable for a gastro-gastric intussusception. An upper gastrointestinal gastrograffin series was ordered (completed only after the pain had subsided) and showed resolution of the intussusception. Histopathology was consistent with a diagnosis of low-grade neuroendocrine tumor (NET). Surgery was initially deferred during the hospitilization given the low grade pathology of the lesion; however further multidisciplinary discussion between Surgery, Oncology, and Gastroenterology recommended resection given the patient's recurrent abdominal pain with the NET functioning as a lead point for further intussusception, and the patient thus underwent robotically-assisted wedge resection. CONCLUSION We present a unique case of severe, intermittent, peri-umbilical pain related to gastro-gastric intussusception caused by an antral NET lead point. The case highlights the importance of considering neoplasms as the cause of intussusception in adults and the greater diagnostic yield when imaging is obtained while symptoms (in this case severe, episodic abdominal pain) are most apparent.
Collapse
Affiliation(s)
- Alex Zhornitskiy
- Department of Internal Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
| | - Long Le
- Department of Internal Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
| | - Serene Tareen
- Department of Internal Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
| | - Gezman Abdullahi
- Department of Internal Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
| | - Deepthi Karunasiri
- Department of Pathology and Laboratory Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
| | - James H Tabibian
- Division of Gastroenterology, Department of Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
| |
Collapse
|
37
|
Balogun OS, Olajide TO, Afolayan M, Lawal A, Osinowo AO, Adesanya AA. An appraisal of the presentation and management of adult intussusception at a Nigerian Tertiary Hospital. Niger Postgrad Med J 2019; 26:169-173. [PMID: 31441455 DOI: 10.4103/npmj.npmj_47_19] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/04/2022]
Abstract
Background Intussusception in adults is considered rare in surgical practice. It is the causative lesion in a small proportion of cases of intestinal obstruction and lower gastrointestinal bleeding. In the last decade, the incidence of adult intussusception appears to be increasing at our centre. Aims This study aims to document the pattern of presentation and management outcome of adult intussusception at our institution during the last decade. We also observed the occurring trends of this lesion. Patients and Methods This was a 10-year retrospective study of consecutive adult patients with intussusception seen at our institution from July 2008 to June 2018. Information on biodata, clinicopathological features and management outcome retrieved from case notes and pathology records were analysed on a personal computer using SPSS version 23. Results Twenty adult patients who had intussusception were seen during this period. There were 9 (45%) males and 11 (55%) females giving a male-to-female ratio of 1:1.2. The mean age of presentation was 45 (range 18-66) years. Clinical features were abdominal pain (85%), abdominal distension (80%), vomiting (70%), rectal bleeding (70%) and palpable abdominal mass (35%). Majority of patients (70%) presented with features of intestinal obstruction. Idiopathic intussusception (55%) accounted for more than half of the cases with the jejunoileal variety (30%) as the most common pathological type. One patient who had intussusception in the postoperative period was treated with manual reduction at laparotomy. Bowel resections were performed in the remaining 19 (95%) patients. Conclusion Adult intussusception is still uncommon in our general surgical practice. Bowel resection is the mainstay of treatment.
Collapse
Affiliation(s)
- Olanrewaju Samuel Balogun
- Department of Surgery, College of Medicine, University of Lagos and Lagos University Teaching Hospital, Lagos, Nigeria
| | - Thomas O Olajide
- Department of Surgery, College of Medicine, University of Lagos and Lagos University Teaching Hospital, Lagos, Nigeria
| | - Michael Afolayan
- Department of Surgery, College of Medicine, University of Lagos and Lagos University Teaching Hospital, Lagos, Nigeria
| | - Abdulrazzak Lawal
- Department of Surgery, College of Medicine, University of Lagos and Lagos University Teaching Hospital, Lagos, Nigeria
| | - Adedapo Olumide Osinowo
- Department of Surgery, College of Medicine, University of Lagos and Lagos University Teaching Hospital, Lagos, Nigeria
| | - Adedoyin A Adesanya
- Department of Surgery, College of Medicine, University of Lagos and Lagos University Teaching Hospital, Lagos, Nigeria
| |
Collapse
|
38
|
Al-Shaibi MA, Raniga SB, Asghar ANM, Al Tubi IS. Caecal duplication cyst leading to intussusception in an adult. BMJ Case Rep 2019; 12:e230567. [PMID: 31511265 PMCID: PMC6738667 DOI: 10.1136/bcr-2019-230567] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 08/27/2019] [Indexed: 12/12/2022] Open
Abstract
Colonic duplication cyst is an uncommon cause of intussusception in adults. We report a case of caecal duplication cyst in a 24-year-old adult with a 3-year history of recurrent abdominal pain mainly in the periumbilical region. CT and MRI of the abdomen showed a lesion suggesting an caecal duplication cyst within an intussuception. The patient underwent diagnostic laparoscopy and was found to have a caecal duplication cyst acting as a lead point for the intusseception for which laparoscopic-assisted resection was performed. The histological examination confirmed the presence of intestinal duplication cyst without any underlying malignancy.
Collapse
Affiliation(s)
- Maha A Al-Shaibi
- Department of Surgery, Sultan Qaboos University Hospital, Muscat, Oman
| | - Sameer B Raniga
- Radiology Department, Sultan Qaboos University Hospital, Muscat, Oman
| | - Abdul N M Asghar
- Department of Surgery, Sultan Qaboos University Hospital, Muscat, Oman
| | - Ikhtiyar S Al Tubi
- Department of General Surgery, Oman Medical Speciality Board, Al-Athaiba, Oman
| |
Collapse
|
39
|
Aukhojee V, Gilong CM, Seewoogoolam G, Strauss PN. Rare presentation of ileocolic intussusception secondary to mantle cell lymphoma. BMJ Case Rep 2019; 12:e229425. [PMID: 31420425 PMCID: PMC6700590 DOI: 10.1136/bcr-2019-229425] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 07/27/2019] [Indexed: 11/04/2022] Open
Abstract
Mantle cell lymphoma is a type of B-cell non-Hodgkin's lymphoma (NHL) and accounts for 3%-6% of all adult NHL.1 2 Bowel intussusception secondary to lymphoma is rare in adults, accounting for only 4% of all cases.3The authors present the case of a 53-year-old man, recently diagnosed with mantle cell lymphoma, who presented with sudden onset right-sided abdominal pain and was found to have ileocolic intussusception up to the hepatic flexure on abdominal CT. He underwent an emergency right hemicolectomy and intraoperatively, the terminal ileum could be seen telescoping into the caecum, up to the hepatic flexure. Although intussusception is uncommon in the adult population, an underlying bowel pathology should always be considered and prompt imaging should be organised to confirm the diagnosis and allow initiation of management in a timely manner.
Collapse
Affiliation(s)
- Veeresh Aukhojee
- Department of Surgery, Austin Health, Heidelberg, Victoria, Australia
| | - Creski M Gilong
- Department of Surgery, Austin Health, Heidelberg, Victoria, Australia
| | | | - Paul N Strauss
- General Surgery, Central Gippsland Health Service, Sale, Victoria, Australia
| |
Collapse
|
40
|
de Mesquita GHA, Carvalho BJ, de Almeida Medeiros KA, Nii F, Martines DR, Pipek LZ, Jardim YJ, Waisberg DR, Obara MT, Sitnik R, Meyer A, Mangueira CLP. Intussusception reveals MUTYH-associated polyposis syndrome and colorectal cancer: a case report. BMC Cancer 2019; 19:324. [PMID: 30953464 PMCID: PMC6451307 DOI: 10.1186/s12885-019-5505-8] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/16/2018] [Accepted: 03/21/2019] [Indexed: 12/20/2022] Open
Abstract
BACKGROUND We are reporting a rare case of MUTYH-associated polyposis, a colorectal cancer hereditary syndrome, diagnosticated after an intussusception. Colorectal cancer is an important cause of cancer related mortality that can be manifested by an intussusception, a rare occurrence in adults and almost always related to tumors. Approximately 5% of colorectal cancers can be attributed to syndromes known to cause hereditary colorectal cancer, such as MUTYH-associated polyposis, autosomal genetic syndrome associated with this disease. CASE PRESENTATION We present the case of a 44 years old male, that sought medical consultation with a complaint of abdominal discomfort, that after five days changed its characteristics. The patient was sent to the emergency department were a CT-scan revealed intestinal sub-occlusion by ileocolic invagination. Right colectomy was carried out. The anatomic-pathological examination revealed a moderately differentiated mucinous adenocarcinoma and multiples sessile polyps, which led to the suspicion of a genetic syndrome. In the genetics analysis two mutations were observed in the MUTYH gene, and MUTYH-associated polyposis was diagnosticated. CONCLUSION This case demonstrates the importance of meticulous analysis of the patient examinations results to identify possible discrete alterations that can lead to improved understanding of disease.
Collapse
Affiliation(s)
| | | | | | | | | | | | | | - Daniel Reis Waisberg
- Departamento de Gastroenterologia, Hospital das Clínicas, HCFMUSP, São Paulo, Brazil
| | | | | | - Alberto Meyer
- Departamento de Gastroenterologia, Hospital das Clínicas, HCFMUSP, São Paulo, Brazil
- Hospital Israelita Albert Einstein, São Paulo, Brazil
| | | |
Collapse
|
41
|
Aldossary MY, Alzahir AA, Almulla LA, Alhajji ZH, Alsaif OH. Giant Brunner's gland hamartoma causing retrograde jejuno-duodenal intussusception: A case report. Ann Med Surg (Lond) 2019; 38:37-41. [PMID: 30671231 PMCID: PMC6327855 DOI: 10.1016/j.amsu.2018.12.007] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/28/2018] [Accepted: 12/30/2018] [Indexed: 11/30/2022] Open
Abstract
Brunner's gland hamartoma is a rare benign duodenal tumor. It occurs in Brunner's glands, which are found in the duodenum and produce secretions that protect the duodenum from pancreatic enzymes, gastric acid, and other agents. Endoscopic or surgical resection is required for these hamartomas. Duodenal intussusception is a relatively rare condition, usually caused by the presence of benign tumors, such as fibroadenomas, lipomas, papillomas, or sometimes with malignant neoplasms. We report a case of giant Brunner's gland hamartoma in the duodenum causing antiperistaltic intussusception in a 45-year-old female patient. The patient reported a 3-year history of chronic anemia, and this mass was detected incidentally by computed tomography (CT) during investigations for chronic anemia and weight loss. Pre-operative abdominal and pelvis contrast revealed a sausage-shaped intraluminal structure with alternating fat planes and vessels distended in the third part of the duodenum up to the first part of the duodenum. Pancreas-sparing duodenectomy was performed. The patient recovered very slowly and was discharged on postoperative day 15 in good condition. Histology showed a large polypoid mass measuring 12.0 × 7.5 × 2.0 cm3, consistent with Brunner's gland hamartoma. Brunner's gland hamartoma can present with features of duodenal intussusception or ampullary obstruction but is rarely seen to cause retrograde jejuno-duodenal intussusception. Pancreas-sparing duodenectomy is the best surgical option in adult patients with intestinal intussusception associated with giant lesions close to the ampulla of Vater, especially in the presence of features of malignancy.
Brunner's gland hamartoma is a rare benign duodenal tumor. Adult intussusception is usually caused by benign or malignant tumors, but rarely to be caused by Brunner's gland hamartoma. Pancreas-sparing duodenectomy is the surgical option for lesions close to the ampulla of Vater.
Collapse
Affiliation(s)
- Mohammed Yousef Aldossary
- Department of General Surgery, Surgical Oncology Section, King Fahad Specialist Hospital-Dammam, Saudi Arabia
| | - Ali A Alzahir
- Department of General Surgery, Surgical Oncology Section, King Fahad Specialist Hospital-Dammam, Saudi Arabia
| | - Liqa A Almulla
- Department of Pathology and Laboratory Medicine, Histopathology Consultant, King Fahad Specialist Hospital-Dammam, Saudi Arabia
| | - Zahrah H Alhajji
- Department of General Surgery, Surgical Oncology Section, King Fahad Specialist Hospital-Dammam, Saudi Arabia
| | - Osama H Alsaif
- Department of General Surgery, Surgical Oncology Section, King Fahad Specialist Hospital-Dammam, Saudi Arabia
| |
Collapse
|
42
|
Farkas NG, Welman TJP, Ross T, Brown S, Smith JJ, Pawa N. Unusual causes of large bowel obstruction. Curr Probl Surg 2018; 56:49-90. [PMID: 30777150 DOI: 10.1067/j.cpsurg.2018.12.001] [Citation(s) in RCA: 10] [Impact Index Per Article: 1.4] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/25/2018] [Accepted: 12/10/2018] [Indexed: 12/17/2022]
Affiliation(s)
- Nicholas G Farkas
- West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
| | - Ted Joseph P Welman
- West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
| | - Talisa Ross
- West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
| | - Sarah Brown
- West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
| | - Jason J Smith
- West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
| | - Nikhil Pawa
- West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
| |
Collapse
|
43
|
Ermolov AS, Yartsev PA, Lebedev AG, Kirsanov II, Selina IE, Shavrina NV, Rogal MM, Kaloeva OK, Kazakova VV. [Ileocecal intussusceptions]. Khirurgiia (Mosk) 2018:77-81. [PMID: 30307427 DOI: 10.17116/hirurgia2018090177] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/18/2022]
Abstract
AIM To present treatment of patients with ileocecal intussusception. MATERIAL AND METHODS There were 3 patients with ileocecal intussusception for the period from June 2016 to August 2017. CONCLUSION Abdominal sonography is main diagnostic method for intestinal intussusception. X-ray examination including contrast-enhanced irrigography gives more complete information about suspected intussusception. It is necessary to differentiate intestinal intussusception from other diseases accompanied by abdominal pain, vomiting, bloody discharge from rectum, abdominal neoplasm. Minimally invasive laparoscopic approach is advisable for diagnosis and treatment of intestinal intussusception.
Collapse
Affiliation(s)
- A S Ermolov
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - P A Yartsev
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - A G Lebedev
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - I I Kirsanov
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - I E Selina
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - N V Shavrina
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - M M Rogal
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - O Kh Kaloeva
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| | - V V Kazakova
- Sklifosovsky Research Institute for Emergency Care of Moscow Healthcare Department, Moscow, Russia
| |
Collapse
|
44
|
Kimura S, Iida H, Gunji N, Gohongi T, Ogata T. Stool filling of an intestinal duplication cyst at the ileocecal valve triggers colonic intussusception: a case report. Surg Case Rep 2018; 4:116. [PMID: 30219978 PMCID: PMC6139107 DOI: 10.1186/s40792-018-0527-z] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/12/2018] [Accepted: 09/10/2018] [Indexed: 02/04/2023] Open
Abstract
Background Intestinal duplication, a congenital malformation, is considered a rare condition, particularly in adults. Although it affects young children, a minority of patients remains asymptomatic until adulthood. Here, we describe a case of an intestinal duplication cyst that caused intussusception by a unique mechanism. Case presentation A 19-year-old man was admitted to our hospital for intermittent abdominal pain. Computed tomography revealed colonic intussusception induced by a nodular mass in the ileocecal region. Urgent ileocecal resection was performed because of the risk of colonic ischemia. The resected material comprised a stool-filled noncommunicating cyst that protruded into the enteric lumen at the ileocecal valve. Histological analyses revealed that the inner wall of the cyst was lined with colonic mucosa and that the muscle layer of the cyst was shared with that of the original enteric wall; furthermore, the cyst had a vestige of an opening site in the wall. We concluded that the cyst was an intestinal duplication that poured stool into its lumen through the tiny orifice, thereby triggering intussusception. Conclusions The present case suggests that stool-pouring can cause intussusception into the space of an intestinal duplication lesion.
Collapse
Affiliation(s)
- Sota Kimura
- Department of Surgery, Tsukuba Gakuen Hospital, 2573-1 Kamiyokoba, Tsukuba, Ibaraki, 305-0854, Japan.
| | - Hiroyuki Iida
- Department of Surgery, Tsukuba Gakuen Hospital, 2573-1 Kamiyokoba, Tsukuba, Ibaraki, 305-0854, Japan
| | - Naoto Gunji
- Department of Surgery, Tsukuba Gakuen Hospital, 2573-1 Kamiyokoba, Tsukuba, Ibaraki, 305-0854, Japan
| | - Takeshi Gohongi
- Department of Surgery, Tsukuba Gakuen Hospital, 2573-1 Kamiyokoba, Tsukuba, Ibaraki, 305-0854, Japan
| | - Takesaburo Ogata
- Department of Pathology, Tsukuba Gakuen Hospital, 2573-1 Kamiyokoba, Tsukuba, Ibaraki, 305-0854, Japan
| |
Collapse
|
45
|
Behrooz A, Cleasby M. Gastrogastric intussusception in adults: a case report with review of the literature. BJR Case Rep 2018; 4:20180006. [PMID: 30931134 PMCID: PMC6438400 DOI: 10.1259/bjrcr.20180006] [Citation(s) in RCA: 8] [Impact Index Per Article: 1.1] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/02/2018] [Revised: 04/26/2018] [Accepted: 05/10/2018] [Indexed: 01/02/2023] Open
Abstract
Intussusception of the gastrointestinal viscera is rarely encountered in adult patients and is frequently associated with a polypoidal lead point, which is often malignant. We would like to present the case of a 68-year-old male with a history of decompensated liver disease and multiple medical comorbidities, who was discovered to have an incidental gastrogastric intussusception on CT. No polypoidal lead point was seen and we believe this to be the first case of its kind to be described. We suggest that distortions in the patient’s visceral and vascular anatomy and raised intra-abdominal pressure resulting from concomitant ascites, hiatus hernia, portal hypertension and oesophageal varices have provided an alternative mechanism for a gastrogastric intussusception to develop.
Collapse
Affiliation(s)
- Arash Behrooz
- Department of Pathology, Worcestershire Royal Hospital, Worcester, UK
| | - Morgan Cleasby
- Department of Radiology, Good Hope Hospital, Birmingham, UK
| |
Collapse
|
46
|
Retrospective analysis of cases of intestinal invagination treated and followed-up at our clinic. North Clin Istanb 2017; 4:141-144. [PMID: 28971171 PMCID: PMC5613261 DOI: 10.14744/nci.2017.19970] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/19/2017] [Accepted: 05/18/2017] [Indexed: 12/26/2022] Open
Abstract
OBJECTIVE: The purpose of this study was to present data on the diagnosis, treatment, clinical course, and outcome of cases of intestinal invagination. METHODS: Data of 11 patients treated for intestinal invagination at one center between June 2009 and July 2015 were analyzed retrospectively in terms of demographic data, etiological factors, anatomical localization of invagination, admission complaints, physical examination findings, diagnostic imaging modalities used, postoperative complications, and hospital stay. RESULTS: Of the total, 9 (81.8%) patients were female and 2 (18.2%) were male. Nine (81.8%) cases occurred due to benign causes and 2 to malignant causes. One (9%) patient had jejunojejunal invagination, 5 (45.5%) had ileoileal invagination, and 5 (45.5%) had ileocecal invagination. Right hemicolectomy-ileotransversostomy was performed in 5 (45.5%) patients and segmental small bowel resection with end-to-end anastomosis in 6 (54.5%). CONCLUSION: Intestinal invagination is a rare cause of acute abdomen in adults that may have a variety of etiologies and therefore may present with different clinical pictures. Abdominal pain, nausea, and vomiting are the most common symptoms. The rate of accurate diagnosis is 30% to 35% using ultrasonography and 50% to 80% using computerized tomography. In adults, the preferred treatment is surgery. As malignant pathologies are responsible for some cases of invagination, oncological principles should be strictly observed in surgical treatment. Though a rare cause of acute abdomen and/or ileus in adults, invagination is a clinical condition that must be kept in mind in the differential diagnosis.
Collapse
|
47
|
Rafailidis V, Phillips C, Yusuf G, Sidhu P. A case of adult intussusception with greyscale, contrast-enhanced ultrasound and computerised tomography correlation. ULTRASOUND : JOURNAL OF THE BRITISH MEDICAL ULTRASOUND SOCIETY 2016; 25:120-125. [PMID: 28567107 DOI: 10.1177/1742271x16678646] [Citation(s) in RCA: 5] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 07/14/2016] [Accepted: 10/20/2016] [Indexed: 12/24/2022]
Abstract
Intussusception is often misdiagnosed as a cause of bowel ischemia and obstruction among adults due to its relatively rare presentation outside of the paediatric population. Ultrasound is often the first-line investigation for non-specific abdominal pain and can identify the presence of intussusception. In the adult population, it is essential to evaluate for causes and consequences of intussusception; as a result, computerised tomography is often deemed necessary. However, contrast-enhanced ultrasound allows for evaluation of potential causes and complications, including a neoplastic lead point and ischaemia of the bowel, whilst avoiding ionising radiation or nephrotoxic iodinated contrast. We report a case of adult intussusception with a polyp lead point with ultrasound, contrast-enhanced ultrasound and computerised tomography correlation.
Collapse
Affiliation(s)
| | | | - Gibran Yusuf
- Department of Radiology, King's College Hospital, London, UK
| | - Paul Sidhu
- Department of Radiology, King's College Hospital, London, UK
| |
Collapse
|
48
|
de Figueiredo LO, Garcia DPC, Alberti LR, Paiva RA, Petroianu A, Paolucci LB, Costa MRLG. Colo-colonic intussusception due to large submucous lipoma: A case report. Int J Surg Case Rep 2016; 28:107-110. [PMID: 27693869 PMCID: PMC5048079 DOI: 10.1016/j.ijscr.2016.09.006] [Citation(s) in RCA: 8] [Impact Index Per Article: 0.9] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/16/2016] [Accepted: 09/19/2016] [Indexed: 02/08/2023] Open
Abstract
Intussusception is rare cause of chronic abdominal pain in adults. Colo-colonic intussusceptions caused by large submucous lipoma. Adults intusseption is rarely caused by idiopathic condition. Main causes are inflammatory diseases, benign or malignant tumors, adhesions and other mechanical conditions impairing peristalsis leading to chronic diarrhea. Inflammatory diseases, tumors, adhesions or mechanical conditions may lead to this patology. Colonoscopy contributes to diagnosis given that it provides direct visualization and biopsy. Introduction Intussusception in adult is rarely caused by idiopathic conditions. Main causes are inflammatory diseases, benign or malignant tumors and motility disorders. As a benign cause, lipomas appear as a particularly rare gastrointestinal intraluminal tumor occurring with highest incidence in the colon, mostly in the caecum and ascending colon. Presentation of case A 57-year-old male patient was admitted at the surgical emergency in Belo Horizonte, with history of chronic and intermittent diffuse abdominal pain, associated with variations of his bowel habits and rare episodes of vomiting starting around 3 days prior to admission. Discussion Intussusception is the cause of adult symptomatic bowel obstruction in 1% of the cases and its colocolonic occurrence represents 17% of all intestinal intussusceptions in adults. The reported case presents itself as even rarer considering its evaluation according to the epidemiological statistics of 1:5 men/women ratio and lipoma’s most common location being the right colon. Intussusception and intestinal obstructions caused by intraluminal lipomas are not often described in the literature and its occurrence is directly related to its size, usually larger than 2 cm diameter. The management of lipomatous intraluminal lesions of the colon is traditionally surgical, and it allows a selective resection, depending on the size of the tumor, length of intussusception, and the amount of inflammation. Conclusion Patients with chronic abdominal symptoms and semi-obstruction caused by intussusception are rarely diagnosed before surgery unless there is a high index of suspicion. Colonoscopy contributes to diagnosis given that it provides direct visualization and biopsy.
Collapse
Affiliation(s)
| | - D P C Garcia
- Department of Surgery, Instituto de Ensino e Pesquisa da Santa Casa, Belo Horizonte, MG, Brazil
| | - Luiz Ronaldo Alberti
- Department of Surgery, FMUFMG and Instituto de Ensino e Pesquisa da Santa Casa, Belo Horizonte, MG, Brazil
| | - R A Paiva
- Colorectal Surgeon at Hospital Felício Rocho, Av do Contorno 9530, 30110-130, Belo Horizonte, MG, Brazil
| | - Andy Petroianu
- FMUFMG and Instituto de Ensino e Pesquisa da Santa Casa, Belo Horizonte, MG, Brazil
| | | | | |
Collapse
|