Submit a Manuscript
Scan QR Codes
  • Homepage
  • Online Submission
  • Journal List
  • Management System
Manuscript Statistics
Articles In Press
1
Karch SB, Fineschi V, Francia P, Scopetti M, Padovano M, Manetti F, Santurro A, Frati P, Volpe M. Role of induced pluripotent stem cells in diagnostic cardiology. World J Stem Cells 2021; In press
2021-04-14 | Browse: 11 | Download: 0
2
Pérez Lara FJ, Jimenez Martinez MB, Pozo Muñoz F, Fontalba Navas A, Garcia Cisneros R, Garcia Larrosa MJ, Garcia Delgado I, Callejon Gil MDM. COVID-19 pandemic, as experienced in the surgical service of a district hospital in Spain. World J Clin Cases 2021; In press
2021-04-14 | Browse: 13 | Download: 0
3
Visani M, Acquaviva G, De Leo A, Sanza V, Merlo L, Maloberti T, Brandes AA, Franceschi E, Di Battista M, Masetti M, Jovine E, Fiorino S, Pession A, Tallini G, de Biase D. Molecular alterations in pancreatic tumors. World J Gastroenterol 2021; In press
2021-04-14 | Browse: 11 | Download: 0
4
Sager O, Dincoglan F, Demiral S, Uysal B, Gamsiz H, Colak O, Ozcan F, Gundem E, Elcim Y, Dirican B, Beyzadeoglu M. Concise review of stereotactic irradiation for pediatric glial neoplasms: Current concepts and future directions. World J Methodol 2021; In press
2021-04-14 | Browse: 12 | Download: 1
5
Mahapatra R, Mahanta D, Singh J, Acharya D, Barik R. Device closure of left lower pulmonary artery to left atrial fistula using a vascular plug: A case report. World J Cardiol 2021; In press
2021-04-14 | Browse: 37 | Download: 9
6
Liu X, Cheng YW, Shao L, Sun SH, Wu J, Song QH, Zou HS, Ling ZX. Gut microbiota dysbiosis in Chinese children with type 1 diabetes mellitus: An observational study. World J Gastroenterol 2021; In press
2021-04-14 | Browse: 11 | Download: 2
7
Montada-Atin T, Prasad GVR. Recent advances in new-onset diabetes mellitus after kidney transplantation. World J Diabetes 2021; In press
2021-04-14 | Browse: 10 | Download: 0
8
D'Souza SM, Houston K, Keenan L, Yoo BS, Parekh PJ, Johnson DA. Role of microbial dysbiosis in the pathogenesis of esophageal mucosal disease: A paradigm shift from acid to bacteria? World J Gastroenterol 2021; In press
2021-04-14 | Browse: 15 | Download: 0
9
Farina AR, Cappabianca LA, Zelli V, Sebastiano M, Mackay AR. Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting. World J Stem Cells 2021; In press
2021-04-14 | Browse: 18 | Download: 0
10
Campanella S. Use of cognitive event-related potentials in the management of psychiatric disorders: Towards an individual follow-up and multi-component clinical approach. World J Psychiatr 2021; In press
2021-04-14 | Browse: 20 | Download: 0
11
Alemany M. Estrogens and the regulation of glucose metabolism. World J Diabetes 2021; In press
2021-04-14 | Browse: 18 | Download: 0
12
Garg P, Goyal A, Yagnik V, Dawka S, Menon GR. Diagnosis of anorectal tuberculosis by polymerase chain reaction, GeneXpert and histopathology in 1336 samples in 776 anal fistula patients. World J Gastrointest Surg 2021; In press
2021-04-14 | Browse: 17 | Download: 10
13
Toyoshima O, Nishizawa T, Yoshida S, Aoki T, Nagura F, Sakitani K, Tsuji Y, Nakagawa H, Suzuki H, Koike K. Comparison of endoscopic gastritis based on Kyoto classification between diffuse and intestinal gastric cancer. World J Gastrointest Endosc 2021; In press
2021-04-14 | Browse: 21 | Download: 1
14
King R, Hayes C, Donohoe CL, Dunne MR, Davern M, Donlon NE. Hypoxia and its impact on the tumour microenvironment of gastroesophageal cancers. World J Gastrointest Oncol 2021; In press
2021-04-14 | Browse: 19 | Download: 0
15
Grosek J, Zavrtanik H, Tomažič A. Health-related quality of life after curative resection for gastric adenocarcinoma. World J Gastroenterol 2021; In press
2021-04-14 | Browse: 28 | Download: 2
16
Cherri S, Noventa S, Zaniboni A. Pancreatic adenocarcinoma: Beyond first line, where are we? World J Gastroenterol 2021; In press
2021-04-14 | Browse: 18 | Download: 0
17
Bolzacchini E, Nigro O, Inversini D, Giordano M, Maconi G. Intestinal metastasis from breast cancer: Presentation, treatment and survival from a systematic literature review. World J Clin Oncol 2021; In press
2021-04-14 | Browse: 18 | Download: 0
18
Li WJ, Archontakis-Barakakis P, Palaiodimos L, Kalaitzoglou D, Tzelves L, Manolopoulos A, Wang YC, Giannopoulos S, Faillace R, Kokkinidis DG. Dabigatran, rivaroxaban, and apixaban compared to warfarin in Asian patients with non-valvular atrial fibrillation: An updated meta-analysis. World J Cardiol 2021; In press
2021-04-14 | Browse: 21 | Download: 0
19
Umano GR, Di Sessa A, Guarino S, Gaudino G, Marzuillo P, Miraglia del Giudice E. Telemedicine in the COVID-19 era: Taking care of children with obesity and diabetes mellitus. World J Diabetes 2021; In press
2021-04-14 | Browse: 17 | Download: 0
20
Rojas A, Schneider I, Lindner C, Gonzàlez I, Morales MA. Receptor for advanced glycation end-products axis and COVID-19 in inflammatory bowel diseases: A dangerous liaison? World J Gastroenterol 2021; In press
2021-04-14 | Browse: 17 | Download: 0
323 items  Read more >>
Author Reviews
1
"Thanks to the entire team of the Journal for their help in publishing the paper, from the editors to the reviewers. Always available to help throughout the process, from submission to publication. The only thing, as a corresponding Author, I have not always received communications, a problem that is however contained thanks to the availability of the editorial group."
Zippi M, Fiorino S, Budriesi R, Micucci M, Corazza I, Pica R, de Biase D, Gallo CG, Hong W. Paradoxical relationship between proton pump inhibitors and COVID-19: A systematic review and meta-analysis. World J Clin Cases 2021; 9(12): 2763-2777 [DOI: 10.12998/wjcc.v9.i12.2763]
2
"Fantastic well done Baishideng Publishing Group"
Vij M, Calderaro J. Pathologic and molecular features of hepatocellular carcinoma: An update. World J Hepatol 2021; 13(4): 393-410 [DOI: 10.4254/wjh.v13.i4.393]
3
"Excellent"
Taweesedt PT, Surani S. Mediastinal lymphadenopathy in COVID-19: A review of literature. World J Clin Cases 2021; 9(12): 2703-2710 [DOI: 10.12998/wjcc.v9.i12.2703]
4
"Satisfying Experience."
Shi X, Cai YT, Cai X, Wen XL, Wang JY, Ma WC, Shen J, Wu JX, Liu HY, Sun J, He PQ, Lin Y, Zhao DY, Li PQ. Management and implementation strategies of pre-screening triage in children during coronavirus disease 2019 pandemic in Guangzhou, China. World J Clin Cases 2021; 9(12): 2731-2738 [DOI: 10.12998/wjcc.v9.i12.2731]
5
"I am totally satisfied with the services of WJD throughout the whole process, from article submission, to peer review and online publication. I would definitely suggest WJD to my colleagues for paper submission."
Serbis A, Giapros V, Kotanidou EP, Galli-Tsinopoulou A, Siomou E. Diagnosis, treatment and prevention of type 2 diabetes mellitus in children and adolescents. World J Diabetes 2021; 12(4): 344-365 [DOI: 10.4239/wjd.v12.i4.344]
6
"I'm satisfied with all the process, thank you."
Wang HC, Lu W, Gao ZH, Xie YN, Hao J, Liu JM. Application of a rapid exchange extension catheter technique in type B2/C nonocclusive coronary intervention via a transradial approach. World J Clin Cases 2021; 9(12): 2751-2762 [DOI: 10.12998/wjcc.v9.i12.2751]
7
"Thank you very much"
Hu WK, Liu J, Liu RX, Liu XW, Yin CH. Congenital bilateral cryptorchidism in an infant conceived after maternal breast cancer treatment: A case report. World J Clin Cases 2021; 9(12): 2923-2929 [DOI: 10.12998/wjcc.v9.i12.2923]
8
"Thank you very much for the hard work of all the experts. I hope the journal of WJCC will become better and better."
Wu XK, Lin Q. Pulmonary alveolar proteinosis complicated with nocardiosis: A case report and review of the literature. World J Clin Cases 2021; 9(12): 2874-2883 [DOI: 10.12998/wjcc.v9.i12.2874]
9
"Dear Sirs, we are really satisfied with the whole editing, reviewing and publishing process. We thank you for the opportunity to publish on WJCC On behalf of all autors Best regards Alessio Tognarelli, MD"
Tognarelli A, Faggioni L, Erba AP, Faviana P, Durante J, Manassero F, Selli C. Robotically assisted removal of pelvic splenosis fifty-six years after splenectomy: A case report. World J Clin Cases 2021; 9(12): 2868-2873 [DOI: 10.12998/wjcc.v9.i12.2868]
10
"Good submission experience, the overall progress is smooth, but it would be better if the editor's initial opinion to the article could be more detailed."
Zhao LW, Sun J, Wang YY, Hua RM, Tai SC, Wang K, Fan Y. Prostate stromal tumor with prostatic cysts after transurethral resection of the prostate: A case report. World J Clin Cases 2021; 9(12): 2830-2837 [DOI: 10.12998/wjcc.v9.i12.2830]
11
"On behalf of my co-authors,we have reviewed the final version of the manuscript and approve it for publication Thank you very much for your attention and consideration."
Huang KX, He C, Yang YL, Huang D, Jiang ZX, Li BG, Liu H. Positive reverse transcription-polymerase chain reaction assay results in patients recovered from COVID-19: Report of two cases. World J Clin Cases 2021; 9(12): 2816-2822 [DOI: 10.12998/wjcc.v9.i12.2816]
12
"I am satisfied with the journal."
Wu ZF, Lu LJ, Zheng HY, Tu Y, Shi Y, Zhou ZH, Fang LX, Fu BP. Separated root tip formation associated with a fractured tubercle of dens evaginatus: A case report. World J Clin Cases 2021; 9(12): 2944-2950 [DOI: 10.12998/wjcc.v9.i12.2944]
13
"Too much content is required to provide in the system."
Chen H, Yang L, Cheng L, Hu XH, Shen YM. Distribution and drug resistance of pathogens in burn patients in China from 2006 to 2019. World J Clin Cases 2021; 9(10): 2228-2237 [DOI: 10.12998/wjcc.v9.i10.2228]
14
"Big problem! I cant see Video 1 only. I can't see Video 2! Please solve this problem immediately."
Akahoshi K, Tamura S, Akahoshi K, Kaneshiro Y, Sashihara R, Uemura K, Sato K. Vinyl bag cover method to avoid droplet-containing aerosol escape from endoscopic forceps channel caps during COVID-19 pandemic (with video). World J Gastrointest Endosc 2021; 13(4): 111-114 [DOI: 10.4253/wjge.v13.i4.111]
15
"First of all, I would like to thank the publishers for their valuable suggestions in the publishing process of this manuscript.Before submitting this manuscript, I also had a detailed understanding of this journal and praised it unanimously. I also trust this journal very much.The journal peer review also raised problems with my manuscript, and I revised it according to the peer review, which improved the quality of my manuscript.Through this submission I also have a further understanding of the journal, but also more trust in the work of the journal."
Ding L, Xu WJ, Tao XY, Zhang L, Cai ZG. Clinicopathological features of superficial CD34-positive fibroblastic tumor. World J Clin Cases 2021; 9(12): 2739-2750 [DOI: 10.12998/wjcc.v9.i12.2739]
16
"On behalf of my co-authors, we deeply appreciate the efficient and professional processing of our paper by your team. However, because we have done language editing work according to the author guidelines when submitting the manuscript, we hope that the time interval for language polishing can be shortened during the entire manuscript processing."
Ma YH, Tian ZS, Liu HC, Zhang BY, Zhu YH, Meng CY, Liu XJ, Zhu QS. Predictive risk factors for recollapse of cemented vertebrae after percutaneous vertebroplasty: A meta-analysis . World J Clin Cases 2021; 9(12): 2778-2790 [DOI: 10.12998/wjcc.v9.i12.2778]
17
"We are really satisfied with the review process and published PDF."
Uchihashi T, Kodama S, Sugauchi A, Hiraoka S, Hirose K, Usami Y, Tanaka S, Kogo M. Salivary duct carcinoma of the submandibular gland presenting a diagnostic challenge: A case report. World J Clin Cases 2021; 9(12): 2908-2915 [DOI: 10.12998/wjcc.v9.i12.2908]
18
"All the authors were very satisfied with the submission process."
Wang CS, Gao Y, Kang K, Fei DS, Meng XL, Liu HT, Luo YP, Yang W, Dai QQ, Gao Y, Zhao MY, Yu KJ. Standardization of critical care management of non-critically ill patients with COVID-19 . World J Clin Cases 2021; 9(12): 2696-2702 [DOI: 10.12998/wjcc.v9.i12.2696]
19
"In my opinion, this is a recommended magazine."
Xie WX, Jiang HT, Shi GQ, Yang LN, Wang H. Behcet’s disease manifesting as esophageal variceal bleeding: A case report. World J Clin Cases 2021; 9(12): 2854-2861 [DOI: 10.12998/wjcc.v9.i12.2854]
20
"The peer review process was fast-tracked and scholarly comments were given for us to improve our manuscript. I appreciate the meticulous effort by the Editors from Journal and Company in ensuring quality submission of our review paper. It certainly motivated my and my team to submit in this journal next time."
Lau Y, Cheng JY, Wong SH, Yen KY, Cheng LJ. Effectiveness of digital psychotherapeutic intervention among perinatal women: A systematic review and meta-analysis of randomized controlled trials. World J Psychiatr 2021; 11(4): 133-152 [DOI: 10.5498/wjp.v11.i4.133]
5493 items  Read more >>
Article Quality Tracking-Peer-Review
1
"I would suggest to extend these results assessing PBC patients as a function of UDCA and obeticholic acid treatment. "
Alamoudi JA, Li W, Gautam N, Olivera M, Meza J, Mukherjee S, Alnouti Y. Bile acid indices as biomarkers for liver diseases I: Diagnostic markers. World J Hepatol 2021; 13(4): 433-455 [DOI: 10.4254/wjh.v13.i4.433]
2
"Clinically relevant work"
Tognarelli A, Faggioni L, Erba AP, Faviana P, Durante J, Manassero F, Selli C. Robotically assisted removal of pelvic splenosis fifty-six years after splenectomy: A case report. World J Clin Cases 2021; 9(12): 2868-2873 [DOI: 10.12998/wjcc.v9.i12.2868]
3
"Clinically relevant work"
Zippi M, Fiorino S, Budriesi R, Micucci M, Corazza I, Pica R, de Biase D, Gallo CG, Hong W. Paradoxical relationship between proton pump inhibitors and COVID-19: A systematic review and meta-analysis. World J Clin Cases 2021; 9(12): 2763-2777 [DOI: 10.12998/wjcc.v9.i12.2763]
4
"Very good article"
Ye QB, Huang QF, Luo YC, Wen YL, Chen ZK, Wei AL. Budd-Chiari syndrome associated with liver cirrhosis: A case report. World J Clin Cases 2021; 9(12): 2937-2943 [DOI: 10.12998/wjcc.v9.i12.2937]
5
"Very good article"
Hu WK, Liu J, Liu RX, Liu XW, Yin CH. Congenital bilateral cryptorchidism in an infant conceived after maternal breast cancer treatment: A case report. World J Clin Cases 2021; 9(12): 2923-2929 [DOI: 10.12998/wjcc.v9.i12.2923]
6
"Very good article"
Uchihashi T, Kodama S, Sugauchi A, Hiraoka S, Hirose K, Usami Y, Tanaka S, Kogo M. Salivary duct carcinoma of the submandibular gland presenting a diagnostic challenge: A case report. World J Clin Cases 2021; 9(12): 2908-2915 [DOI: 10.12998/wjcc.v9.i12.2908]
7
"Very good article"
Wu XK, Lin Q. Pulmonary alveolar proteinosis complicated with nocardiosis: A case report and review of the literature. World J Clin Cases 2021; 9(12): 2874-2883 [DOI: 10.12998/wjcc.v9.i12.2874]
8
"Very good article"
Jiang Y, Lo R, Lu ZQ, Cheng XB, Xiong L, Luo BF. Successful endoscopic surgery for emphysematous pyelonephritis in a non-diabetic patient with autosomal dominant polycystic kidney disease: A case report. World J Clin Cases 2021; 9(12): 2862-2867 [DOI: 10.12998/wjcc.v9.i12.2862]
9
"Very good article"
Xie WX, Jiang HT, Shi GQ, Yang LN, Wang H. Behcet’s disease manifesting as esophageal variceal bleeding: A case report. World J Clin Cases 2021; 9(12): 2854-2861 [DOI: 10.12998/wjcc.v9.i12.2854]
10
"Interesting paper"
Yuan SY, Xie KF, Yang J. Intramuscular hematoma in rhabdomyolysis patients treated with low-molecular-weight heparin: Report of two cases. World J Clin Cases 2021; 9(12): 2838-2844 [DOI: 10.12998/wjcc.v9.i12.2838]
11
"Interesting paper"
Zhao LW, Sun J, Wang YY, Hua RM, Tai SC, Wang K, Fan Y. Prostate stromal tumor with prostatic cysts after transurethral resection of the prostate: A case report. World J Clin Cases 2021; 9(12): 2830-2837 [DOI: 10.12998/wjcc.v9.i12.2830]
12
"Interesting paper"
Yu TT, Yu H, Cui Y, Liu W, Cui XY, Wang X. Laryngeal myxoma: A case report. World J Clin Cases 2021; 9(12): 2823-2829 [DOI: 10.12998/wjcc.v9.i12.2823]
13
"Interesting paper"
Chen JC, Zhuang DZ, Luo C, Chen WQ. Malignant pheochromocytoma with cerebral and skull metastasis: A case report and literature review. World J Clin Cases 2021; 9(12): 2791-2800 [DOI: 10.12998/wjcc.v9.i12.2791]
14
"Very good article"
Ma YH, Tian ZS, Liu HC, Zhang BY, Zhu YH, Meng CY, Liu XJ, Zhu QS. Predictive risk factors for recollapse of cemented vertebrae after percutaneous vertebroplasty: A meta-analysis . World J Clin Cases 2021; 9(12): 2778-2790 [DOI: 10.12998/wjcc.v9.i12.2778]
15
"Very good article"
Taweesedt PT, Surani S. Mediastinal lymphadenopathy in COVID-19: A review of literature. World J Clin Cases 2021; 9(12): 2703-2710 [DOI: 10.12998/wjcc.v9.i12.2703]
16
"Very good article"
Wang CS, Gao Y, Kang K, Fei DS, Meng XL, Liu HT, Luo YP, Yang W, Dai QQ, Gao Y, Zhao MY, Yu KJ. Standardization of critical care management of non-critically ill patients with COVID-19 . World J Clin Cases 2021; 9(12): 2696-2702 [DOI: 10.12998/wjcc.v9.i12.2696]
17
"This is a very comprehensive, well researched report. The patient was fortunate to have such a million dollar workup and thoughtful follow up. I have only two constructive comments to make. Firstly, a more professional presentation of the EKGs would have been helpful. Magnification of the recovery tracings would enable better presentation of the Q-T interval Secondly, the paper's discussion is too technical for most practicing cardiologists to appreciate. While the conclusions are understandable, the methodology is too complex for a "clinical" journal."
Qiu H, Li HW, Zhang SH, Zhou XG, Li WP. Torsades de pointes episode in a woman with high-grade fever and inflammatory activation: A case report. World J Clin Cases 2021; 9(12): 2899-2907 [DOI: 10.12998/wjcc.v9.i12.2899]
18
"The authors could add a systematic review to further analyze the superficial CD34-positive fibroblastic tumor. "
Ding L, Xu WJ, Tao XY, Zhang L, Cai ZG. Clinicopathological features of superficial CD34-positive fibroblastic tumor. World J Clin Cases 2021; 9(12): 2739-2750 [DOI: 10.12998/wjcc.v9.i12.2739]
19
"Technically, a convincing contribution. Albeit the side comment on the problems with sorting cells using LGR5-antibodies might be of interest to many paople considering LGR5 as the holy grale of intestinal cancer stemness. Another puzzling technical issue is the lack of information on STR-testing of the used cell line clones - they were originally from the ATCC, but only indirectly since in the Acknowledgements, the authors thank Professor McGuckin. Especially when analyzing cell line individual features, the lack of this information diminishes it's usefullness for many scientific nit-pickers like me. I would like to add an alternative interpretation of these, and many similar results on stem cells in CRC cell lines: the fact that LGR5 negative cells and cell lines regularly grow nicely in vitro and when carefully looking on the in vivo data of this manuscript often also in vivo, is regularly ignored by many researchers. The same is in our experience also true for many other of the candidate tumor stem cell markers and even for the funcitonally more convincing side population (classically done by Hoechst staining). Thus, the true level of plasticity in CRC cells is in biological reality most likely indeed very high! Part of this complexity has been adressed in the last part of the discussion - which was a pleasure to read. "
Alharbi SA, Ovchinnikov DA, Wolvetang E. Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines. World J Gastroenterol 2021; 27(15): 1578-1594 [DOI: 10.3748/wjg.v27.i15.1578]
20
"Article "Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges" presents the most important knowledge about the SARS-CoV-2 virus and the impact of the virus on the liver as the importance of inflammation in the pathophysiology of infection and potential therapeutic options."
Ali FEM, Mohammedsaleh ZM, Ali MM, Ghogar OM. Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges. World J Gastroenterol 2021; 27(15): 1531-1552 [DOI: 10.3748/wjg.v27.i15.1531]
6286 items  Read more >>
Peer-Reviewers and Manuscript Statistics
Editorial board members
3701
Peer-reviewers
39662
Manuscripts received today
17
Manuscript reviews today
50
Unhandled manuscripts today
115
Active peer-reviewers today
2301
Reviewer acceptance today
81
Reviewer refusals today
126
Total accepted manuscripts
20559
Total rejected manuscripts
25542
Total peer-reviewers
631606
Total submissions
17639
Baishideng Publishing Group (BPG) publishes 47 peer-reviewed, open-access journals covering a broad range of topics in clinical medicine, as well as several topics in biochemistry and molecular biology, relevant to human health today.
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Read more >>
Sign In
  • BPG Management System
  • F6Publishing-Submit a Manuscript
  • F6Publishing-世界华人消化杂志在线投稿
English
  • English 简体中文
BPG Journals
BPG E-Books
BPG Blog
All Journal Articles
1
Priadko K, Romano M, Vitale LM, Niosi M, De Sio I. Asymptomatic portal vein aneurysm: Three case reports. World J Hepatol 2021; 13(4): 515-521
2021-04-27 | Browse: 13 | Download: 1
2
Flores GL, Barbosa JR, Cruz HM, Miguel JC, Potsch DV, Pilotto JH, Lima DM, Baima Colares JK, Brandão-Mello CE, Pires MMA, da Mota JC, Bastos FI, Lewis-Ximenez LL, Villar LM. Dried blood spot sampling as an alternative for the improvement of hepatitis B and C diagnosis in key populations. World J Hepatol 2021; 13(4): 504-514
2021-04-27 | Browse: 16 | Download: 2
3
Kamada Y, Hori T, Yamamoto H, Harada H, Yamamoto M, Yamada M, Yazawa T, Sasaki B, Tani M, Sato A, Katsura H, Tani R, Aoyama R, Sasaki Y, Okada M, Zaima M. Fatal arterial hemorrhage after pancreaticoduodenectomy: How do we simultaneously accomplish complete hemostasis and hepatic arterial flow? World J Hepatol 2021; 13(4): 483-503
2021-04-27 | Browse: 17 | Download: 0
4
Bernshteyn M, Hu L, Masood U, Sharma AV, Huang D, Sapkota B. Retrospective analysis of complications related to endoscopic retrograde cholangio-pancreatography in patients with cirrhosis vs patients without cirrhosis. World J Hepatol 2021; 13(4): 472-482
2021-04-27 | Browse: 13 | Download: 1
5
Chan KS, Mohan R, Low JK, Junnarkar SP, Huey CWT, Shelat VG. Elderly patients (≥ 80 years) with acute calculous cholangitis have similar outcomes as non-elderly patients (< 80 years): Propensity score-matched analysis. World J Hepatol 2021; 13(4): 456-471
2021-04-27 | Browse: 18 | Download: 4
6
Alamoudi JA, Li W, Gautam N, Olivera M, Meza J, Mukherjee S, Alnouti Y. Bile acid indices as biomarkers for liver diseases: Diagnostic markers. World J Hepatol 2021; 13(4): 433-455
2021-04-27 | Browse: 35 | Download: 12
7
Wong YJ, Kumar R, Chua YJJ, Ang TL. Long-term albumin infusion in decompensated cirrhosis: A review of current literature. World J Hepatol 2021; 13(4): 421-432
2021-04-27 | Browse: 8 | Download: 0
8
Poddighe D, Madiyeva A, Talipova D, Umirbekova B. Infantile giant cell hepatitis with autoimmune hemolytic anemia. World J Hepatol 2021; 13(4): 411-420
2021-04-27 | Browse: 12 | Download: 1
9
Vij M, Calderaro J. Pathologic and molecular features of hepatocellular carcinoma: An update. World J Hepatol 2021; 13(4): 393-410
2021-04-27 | Browse: 60 | Download: 4
10
Wu ZF, Lu LJ, Zheng HY, Tu Y, Shi Y, Zhou ZH, Fang LX, Fu BP. Separated root tip formation associated with a fractured tubercle of dens evaginatus: A case report. World J Clin Cases 2021; 9(12): 2944-2950
2021-04-26 | Browse: 94 | Download: 3
11
Ye QB, Huang QF, Luo YC, Wen YL, Chen ZK, Wei AL. Budd-Chiari syndrome associated with liver cirrhosis: A case report. World J Clin Cases 2021; 9(12): 2937-2943
2021-04-26 | Browse: 82 | Download: 4
12
Wu L, Wang Y, Hu CY, Huang CM. Sclerosing polycystic adenosis of the submandibular gland: Two case reports. World J Clin Cases 2021; 9(12): 2930-2936
2021-04-26 | Browse: 91 | Download: 4
13
Hu WK, Liu J, Liu RX, Liu XW, Yin CH. Congenital bilateral cryptorchidism in infant conceived after maternal breast cancer treatment: A case report. World J Clin Cases 2021; 9(12): 2923-2929
2021-04-26 | Browse: 82 | Download: 5
14
Ma ZY, Yang X. Allogeneic hematopoietic stem cell transplantation in a 3-year-old boy with congenital pyruvate kinase deficiency: A case report. World J Clin Cases 2021; 9(12): 2916-2922
2021-04-26 | Browse: 76 | Download: 3
15
Uchihashi T, Kodama S, Sugauchi A, Hiraoka S, Hirose K, Usami Y, Tanaka S, Kogo M. Salivary duct carcinoma of the submandibular gland presenting a diagnostic challenge: A case report. World J Clin Cases 2021; 9(12): 2908-2915
2021-04-26 | Browse: 87 | Download: 3
16
Qiu H, Li HW, Zhang SH, Zhou XG, Li WP. Torsades de pointes episode in a female with high-grade fever and inflammatory activation: A case report. World J Clin Cases 2021; 9(12): 2899-2907
2021-04-26 | Browse: 74 | Download: 4
17
Liu B, Ren KK, Wang N, Xu XP, Wu J. Timing of convalescent plasma therapy-tips from curing a 100-year-old COVID-19 patient using convalescent plasma treatment: A case report. World J Clin Cases 2021; 9(12): 2890-2898
2021-04-26 | Browse: 82 | Download: 3
18
Kim B, Kim YJ, Park I, Cho JY, Lee KA. Detection of epidermal growth factor receptor-SEPT14 fusion in cell-free DNA of a patient with advanced gastric cancer: A case report. World J Clin Cases 2021; 9(12): 2884-2889
2021-04-26 | Browse: 81 | Download: 4
19
Wu XK, Lin Q. Pulmonary alveolar proteinosis complicated with nocardiosis: A case report and review of literature. World J Clin Cases 2021; 9(12): 2874-2883
2021-04-26 | Browse: 87 | Download: 5
20
Tognarelli A, Faggioni L, Erba AP, Faviana P, Durante J, Manassero F, Selli C. Robotically assisted removal of pelvic splenosis fifty-six years after splenectomy: A case report. World J Clin Cases 2021; 9(12): 2868-2873
2021-04-26 | Browse: 103 | Download: 5
43509 items  Read more >>
Featured Articles
1
Flores GL, Barbosa JR, Cruz HM, Miguel JC, Potsch DV, Pilotto JH, Lima DM, Baima Colares JK, Brandão-Mello CE, Pires MMA, da Mota JC, Bastos FI, Lewis-Ximenez LL, Villar LM. Dried blood spot sampling as an alternative for the improvement of hepatitis B and C diagnosis in key populations. World J Hepatol 2021; 13(4): 504-514
2021-04-16 | Browse: 1 | Download: 0
2
Kamada Y, Hori T, Yamamoto H, Harada H, Yamamoto M, Yamada M, Yazawa T, Sasaki B, Tani M, Sato A, Katsura H, Tani R, Aoyama R, Sasaki Y, Okada M, Zaima M. Fatal arterial hemorrhage after pancreaticoduodenectomy: How do we simultaneously accomplish complete hemostasis and hepatic arterial flow? World J Hepatol 2021; 13(4): 483-503
2021-04-16 | Browse: 0 | Download: 0
3
Wong YJ, Kumar R, Chua YJJ, Ang TL. Long-term albumin infusion in decompensated cirrhosis: A review of current literature. World J Hepatol 2021; 13(4): 421-432
2021-04-16 | Browse: 0 | Download: 0
4
Poddighe D, Madiyeva A, Talipova D, Umirbekova B. Infantile giant cell hepatitis with autoimmune hemolytic anemia. World J Hepatol 2021; 13(4): 411-420
2021-04-16 | Browse: 0 | Download: 0
5
Vij M, Calderaro J. Pathologic and molecular features of hepatocellular carcinoma: An update. World J Hepatol 2021; 13(4): 393-410
2021-04-16 | Browse: 0 | Download: 0
6
Kumaran A, Yeung PM, Tiwari R. Perinephric urinoma, an unusual upper tract presentation of a lower tract injury following retroperitoneoscopy: A case report. World J Clin Urol 2021; 10(1): 1-6
2021-04-15 | Browse: 5 | Download: 0
7
Ma YH, Tian ZS, Liu HC, Zhang BY, Zhu YH, Meng CY, Liu XJ, Zhu QS. Predictive risk factors for the recollapse of cemented vertebrae after percutaneous vertebroplasty: A meta-analysis. World J Clin Cases 2021; 9(12): 2778-2790
2021-04-15 | Browse: 12 | Download: 2
8
Zippi M, Fiorino S, Budriesi R, Micucci M, Corazza I, Pica R, de Biase D, Gallo CG, Hong WD. Paradoxal relationship between proton pump inhibitors and COVID-19: A systematic review and meta-analysis. World J Clin Cases 2021; 9(12): 2763-2777
2021-04-15 | Browse: 5 | Download: 0
9
Jiang SS, Mao CG, Feng YG, Jiang B, Tao SL, Tan QY, Deng B. Circulating tumor cells with epithelial-mesenchymal transition markers as the potential biomarker for the diagnosis of lung cancer. World J Clin Cases 2021; 9(12): 2721-2730
2021-04-15 | Browse: 7 | Download: 1
10
Ilias I, Goulas S, Zabuliene L. Polycystic ovary syndrome: Pathways and mechanisms for possible increased susceptibility to COVID-19. World J Clin Cases 2021; 9(12): 2711-2720
2021-04-15 | Browse: 6 | Download: 1
11
Wang CS, Gao Y, Kang K, Fei DS, Meng XL, Liu HT, Luo YP, Yang W, Dai QQ, Gao Y, Zhao MY, Yu KJ. Standardization of critical care management of non-critically ill patients with coronavirus disease 2019. World J Clin Cases 2021; 9(12): 2696-2702
2021-04-15 | Browse: 5 | Download: 0
12
Liang XY, Jia TX, Zhang M. Intestinal bacterial overgrowth in the early stage of severe acute pancreatitis is associated with acute respiratory distress syndrome. World J Gastroenterol 2021; 27(15): 1643-1654
2021-04-14 | Browse: 26 | Download: 20
13
Li K, Peng YF, Guo JZ, Li M, Zhang Y, Chen JY, Lin TR, Yu X, Yu WD. Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1. World J Gastroenterol 2021; 27(15): 1595-1615
2021-04-14 | Browse: 10 | Download: 28
14
Alharbi SA, Ovchinnikov DA, Wolvetang E. LGR5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines. World J Gastroenterol 2021; 27(15): 1578-1594
2021-04-14 | Browse: 12 | Download: 14
15
Sakai Y, Ohtsuka M, Sugiyama H, Mikata R, Yasui S, Ohno I, Iino Y, Kato J, Tsuyuguchi T, Kato N. Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct . World J Gastroenterol 2021; 27(15): 1569-1577
2021-04-14 | Browse: 10 | Download: 24
16
Tsilimigras DI, Pawlik TM, Moris D. Textbook outcomes in hepatobiliary and pancreatic surgery. World J Gastroenterol 2021; 27(15): 1524-1530
2021-04-14 | Browse: 8 | Download: 24
17
Akahoshi K, Tamura S, Akahoshi K, Kaneshiro Y, Sashihara R, Uemura K, Sato K. Vinyl bag cover method to avoid droplet-containing aerosol escape from endoscopic forceps channel caps during COVID-19 pandemic (with video). World J Gastrointest Endosc 2021; 13(4): 111-114
2021-04-13 | Browse: 13 | Download: 19
18
Passi M, Rahman F, Gurram S, Kumar S, Koh C. Identifying who best tolerates moderate sedation: Results from a National Database of Gastrointestinal Endoscopic Outcomes. World J Gastrointest Endosc 2021; 13(4): 97-110
2021-04-13 | Browse: 6 | Download: 13
19
Frazer A, Tanzer M. Hanging up the surgical cap: Assessing the competence of aging surgeons. World J Orthop 2021; 12(4): 234-245
2021-04-12 | Browse: 14 | Download: 6
20
Bush C, Gagnier JJ, Carpenter J, Bedi A, Miller B. Predictors of clinical outcomes after non-operative management of symptomatic full-thickness rotator cuff tears. World J Orthop 2021; 12(4): 223-233
2021-04-12 | Browse: 7 | Download: 11
4181 items  Read more >>
Published Articles Processes
1
Priadko K, Romano M, Vitale LM, Niosi M, De Sio I. Asymptomatic portal vein aneurysm: Three case reports. World J Hepatol 2021; 13(4): 515-521
2021-04-16 | Browse: 2 | Download: 0
2
Flores GL, Barbosa JR, Cruz HM, Miguel JC, Potsch DV, Pilotto JH, Lima DM, Baima Colares JK, Brandão-Mello CE, Pires MMA, da Mota JC, Bastos FI, Lewis-Ximenez LL, Villar LM. Dried blood spot sampling as an alternative for the improvement of hepatitis B and C diagnosis in key populations. World J Hepatol 2021; 13(4): 504-514
2021-04-16 | Browse: 1 | Download: 1
3
Kamada Y, Hori T, Yamamoto H, Harada H, Yamamoto M, Yamada M, Yazawa T, Sasaki B, Tani M, Sato A, Katsura H, Tani R, Aoyama R, Sasaki Y, Okada M, Zaima M. Fatal arterial hemorrhage after pancreaticoduodenectomy: How do we simultaneously accomplish complete hemostasis and hepatic arterial flow? World J Hepatol 2021; 13(4): 483-503
2021-04-16 | Browse: 0 | Download: 0
4
Bernshteyn M, Hu L, Masood U, Sharma AV, Huang D, Sapkota B. Retrospective analysis of complications related to endoscopic retrograde cholangio-pancreatography in patients with cirrhosis vs patients without cirrhosis. World J Hepatol 2021; 13(4): 472-482
2021-04-16 | Browse: 0 | Download: 0
5
Chan KS, Mohan R, Low JK, Junnarkar SP, Huey CWT, Shelat VG. Elderly patients (≥ 80 years) with acute calculous cholangitis have similar outcomes as non-elderly patients (< 80 years): Propensity score-matched analysis. World J Hepatol 2021; 13(4): 456-471
2021-04-16 | Browse: 1 | Download: 0
6
Alamoudi JA, Li W, Gautam N, Olivera M, Meza J, Mukherjee S, Alnouti Y. Bile acid indices as biomarkers for liver diseases: Diagnostic markers. World J Hepatol 2021; 13(4): 433-455
2021-04-16 | Browse: 0 | Download: 0
7
Wong YJ, Kumar R, Chua YJJ, Ang TL. Long-term albumin infusion in decompensated cirrhosis: A review of current literature. World J Hepatol 2021; 13(4): 421-432
2021-04-16 | Browse: 0 | Download: 0
8
Poddighe D, Madiyeva A, Talipova D, Umirbekova B. Infantile giant cell hepatitis with autoimmune hemolytic anemia. World J Hepatol 2021; 13(4): 411-420
2021-04-16 | Browse: 0 | Download: 0
9
Vij M, Calderaro J. Pathologic and molecular features of hepatocellular carcinoma: An update. World J Hepatol 2021; 13(4): 393-410
2021-04-16 | Browse: 0 | Download: 0
10
Kumaran A, Yeung PM, Tiwari R. Perinephric urinoma, an unusual upper tract presentation of a lower tract injury following retroperitoneoscopy: A case report. World J Clin Urol 2021; 10(1): 1-6
2021-04-15 | Browse: 4 | Download: 0
11
Wu ZF, Lu LJ, Zheng HY, Tu Y, Shi Y, Zhou ZH, Fang LX, Fu BP. Separated root tip formation associated with a fractured tubercle of dens evaginatus: A case report. World J Clin Cases 2021; 9(12): 2944-2950
2021-04-15 | Browse: 3 | Download: 0
12
Ye QB, Huang QF, Luo YC, Wen YL, Chen ZK, Wei AL. Budd-Chiari syndrome associated with liver cirrhosis: A case report. World J Clin Cases 2021; 9(12): 2937-2943
2021-04-15 | Browse: 4 | Download: 0
13
Wu L, Wang Y, Hu CY, Huang CM. Sclerosing polycystic adenosis of the submandibular gland: Two case reports. World J Clin Cases 2021; 9(12): 2930-2936
2021-04-15 | Browse: 6 | Download: 0
14
Hu WK, Liu J, Liu RX, Liu XW, Yin CH. Congenital bilateral cryptorchidism in infant conceived after maternal breast cancer treatment: A case report. World J Clin Cases 2021; 9(12): 2923-2929
2021-04-15 | Browse: 7 | Download: 2
15
Ma ZY, Yang X. Allogeneic hematopoietic stem cell transplantation in a 3-year-old boy with congenital pyruvate kinase deficiency: A case report. World J Clin Cases 2021; 9(12): 2916-2922
2021-04-15 | Browse: 4 | Download: 0
16
Uchihashi T, Kodama S, Sugauchi A, Hiraoka S, Hirose K, Usami Y, Tanaka S, Kogo M. Salivary duct carcinoma of the submandibular gland presenting a diagnostic challenge: A case report. World J Clin Cases 2021; 9(12): 2908-2915
2021-04-15 | Browse: 5 | Download: 0
17
Qiu H, Li HW, Zhang SH, Zhou XG, Li WP. Torsades de pointes episode in a female with high-grade fever and inflammatory activation: A case report. World J Clin Cases 2021; 9(12): 2899-2907
2021-04-15 | Browse: 11 | Download: 0
18
Liu B, Ren KK, Wang N, Xu XP, Wu J. Timing of convalescent plasma therapy-tips from curing a 100-year-old COVID-19 patient using convalescent plasma treatment: A case report. World J Clin Cases 2021; 9(12): 2890-2898
2021-04-15 | Browse: 4 | Download: 0
19
Kim B, Kim YJ, Park I, Cho JY, Lee KA. Detection of epidermal growth factor receptor-SEPT14 fusion in cell-free DNA of a patient with advanced gastric cancer: A case report. World J Clin Cases 2021; 9(12): 2884-2889
2021-04-15 | Browse: 5 | Download: 0
20
Wu XK, Lin Q. Pulmonary alveolar proteinosis complicated with nocardiosis: A case report and review of literature. World J Clin Cases 2021; 9(12): 2874-2883
2021-04-15 | Browse: 5 | Download: 2
19797 items  Read more >>
Keyword Search Published Articles Processes
1
Case report
975
2
Hepatocellular carcinoma
970
3
Gastric cancer
687
4
Colorectal cancer
633
5
Inflammatory bowel disease
530
6
Prognosis
487
7
Liver transplantation
452
8
Ulcerative colitis
436
9
Crohn’s disease
409
10
Helicobacter pylori
398
11
Treatment
383
12
Cirrhosis
374
13
Endoscopy
358
14
Diagnosis
353
15
Meta-analysis
335
16
Hepatitis C virus
327
17
Inflammation
319
18
Magnetic resonance imaging
316
19
Pancreatic cancer
304
20
Surgery
289
40502 items  Read more >>
Reader Comments
1
"Should people with chronic liver disease be vaccinated against COVID-19? Coronavirus disease 2019 (COVID-19) has become a global epidemic. It is not just a threat to public health, but also a major blow to economic development and regional stability. SARS-CoV-2 enters host cells by attaching to angiotensin-converting enzyme 2 (ACE2). ACE2 is not simply located in the respiratory tract, but also in the kidney, heart, skeletal muscle, central nervous system, liver, and gastrointestinal tract. Therefore, patients with severe COVID-19 show multiple organ dysfunction. Distribution of ACE2 in liver was unique. Chai, et al found that ACE2 was more highly expressed in cholangiocytes (59.7%) than hepatocytes (2.6%). The level of ACE2 expression in cholangiocytes was comparable to that in type 2 alveolar cells of the lungs, indicating that the liver impairment in COVID‐19 may be originated from damage to the cholangiocytes in the beginning, not directly infection of hepatocytes. Of course, hepatocyte damage in severe cases can also be indirectly induced by the systemic inflammatory response and abnormal metabolism. According to previous meta-analysis, Abnormal alanine transaminase (ALT), aspartate transaminase (AST) and bilirubin were reported in 15.0%, 15.0%, and 16.7% of all patients. However, the severity of liver impairment, clinical outcomes and mortality rate for patients under different chronic liver disease conditions co-infected with SARS-CoV-2 is less noticed. The present review summarizes the impact of SARS-CoV-2 on different chronic liver disease conditions, exhibited overexpression of ACE2 and cytokine storm overwhelming. These might worsen the liver impairment and increase the mortality rate. SARS-CoV-2 vaccines are regarded as the most effective weapon to end the epidemic. Countries around the world are working intensively to develop and produce vaccines. The consensus was reached that we should get as many people vaccinated as possible in order to achieve herd immunity. People with stable chronic liver disease conditions are capable of being included in clinical trials of mRNA BNT162b2, mRNA-1273 vaccine and CoronaVac, BBIBP-CorV Inactivated vaccine. It has proven to be safe and well tolerated. Consider the poor outcomes and high mortality rate of chronic liver disease co-infected with SARS-CoV-2 as stated in this article, the AASLD Expert Panel propose suggestions that COVID-19 vaccines should be given to all adult patients with chronic liver disease and liver transplant recipients. Moreover, patients with chronic liver disease who are receiving antiviral therapy for HBV or HCV should NOT withhold their medications while receiving the COVID-19 vaccines. Patients with hepatocellular carcinoma undergoing locoregional or systemic therapy should also be considered for vaccination without interruption of their treatment. mRNA COVID-19 vaccines are expected to have a favorable efficacy and safety profile in immunosuppressed patients and should be administered according to their standard dose and schedule. Liver transplant candidates with chronic liver disease should receive the mRNA COVID-19 vaccine prior to transplantation. "
Ali FEM, Mohammedsaleh ZM, Ali MM, Ghogar OM. Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges. World J Gastroenterol 2021; 27(15): 1531-1552 [DOI: 10.3748/wjg.v27.i15.1531]
2
"I recognize that LGR5 and BMI1 are representative intestinal stem cell (ISC) markers. At the same time, LGR5 and BMI1 are also known to colorectal cancer stem cell (CSC) markers. This report referred to the cancer stem cells, using famous two cell lines: Caco-2 and Lovo. Therefore, the authors should discuss the relation between colorectal CSCs and LGR5 more in detail in Introduction and discussion. Moreover, the authors did not refer to the relation between colorectal CSCs and BMI1 at all. In contrast, the authors should reduce amount of the description about the relation between ISCs and Lgr5. ISCs did not relate with the main stream of the report. In discussion, the authors should discuss about underling mechanisms why LGR5-negative cells of Lovo could have stemness nature. For examples, RNA-seq from EYFP-positive or EYFP-negative cells of Lovo could help the understanding of different gene expression profile of CSCs and non-CSCs. Regarding Cell culture, the authors should confirm the possibility of mycoplasma infection. Regarding Figure 1I and 1J, I was concerned about stemness properties of LGR5-negative (EYFP-negative) tumor cells. In Figure 1I and 1J, the number of LGR5-negative cells increased day by day. The finding mean that LGR5-negative cells also had a capacity of producing their descendant (LGR5-negative) cells. Therefore, the authors should compare the productivity of daughter cells of LGR5-positive and LGR5-negtive cells (e.g. MTT assay). Regarding Figure 2, the authors confused ISC markers and CSC markers. The authors should refer to OLFM4, TERT…, as CSC markers, not as ISC markers. And they should displaye the number of samples. Regarding Figure4, the number of samples was too small (n = 3). The authors should perform xenograft experiments enough times to make a statistics analysis."
Alharbi SA, Ovchinnikov DA, Wolvetang E. Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines. World J Gastroenterol 2021; 27(15): 1578-1594 [DOI: 10.3748/wjg.v27.i15.1578]
3
"It is an interesting study that the potential role of CXCL12 isoforms enhancing the metastatic tendency of pancreatic cancer was confirmed. It is wondering if three CXCL12 isotypes have differently interacted with CXCR4 in pancreatic cancer cells."
Cecati M, Giulietti M, Righetti A, Sabanovic B, Piva F. Effects of CXCL12 isoforms in a pancreatic pre-tumour cellular model: Microarray analysis. World J Gastroenterol 2021; 27(15): 1616-1629 [DOI: 10.3748/wjg.v27.i15.1616]
4
"This review summarized the latest findings that COVID-19 exacerbate liver damage of liver diseases and the latest treatment recommendations for these kinds of patient. This review first pointed out that the SARS-CoV-2 infection caused a large proportion of patients with liver function abnormalities, and the patients with pre-existing liver disease (ALD, NAFLD, HBV or HCV infection) were more susceptible to the COVID-19 induced liver damage or drug-induced liver damage during the treatment. On the other hand, the author further proposed the mechanism of liver damage in this process, such as direct virus damage, cytokine storm, coagulative and fibrinolytic pathways. Finally, the author also listed the current recommendations for diagnosing and treating COVID-19 infection, in particular, for patients with pre-existing liver disease. However, there are also some ambiguities. For example, some of the data in Figure 1 showed the liver function abnormalities after COVID-19 infection, and others were the data about the liver damage in patients with pre-existing liver disease after COVID-19 infection."
Ahmad A, Ishtiaq SM, Khan JA, Aslam R, Ali S, Arshad MI. COVID-19 and comorbidities of hepatic diseases in a global perspective. World J Gastroenterol 2021; 27(13): 1296-1310 [PMID: 33833483 DOI: 10.3748/wjg.v27.i13.1296]
5
"The authors seem to deal with an important topic carrying on HCV cure in pediatric patient. The study rational, aim and research motivation are relevant and enough well stated. The bibliographic search method seems to be omitted as well as the search date or period. The findings and/or conclusion answer to the study aim to a degree: “No pediatric studies with the children completing the DAA therapy has revealed evidence of children being unresponsive to DAA therapies. However, for patients with evidence of high-grade fibrosis or cirrhosis, they are still at high risk of developing HCC even after achieving SVR. Solid organ transplant from HCV infected recipients appears to be safe, is associated with excellent outcomes, and should be considered for recipients who would benefit from receiving an organ earlier than they would if they waited for an organ from an uninfected donor. Thus, reducing wait-list associated mortality. While no studies has been performed, based on the efficacy of DAA therapy in children, using HCV-infected donors should be an option. As children will now have access to DAA therapies and potential HCV cure, it is imperative that diagnosis and treatment of this population is not overlooked. A related issue is for patients with chronic liver disease to avoid COVID-19 exposure and infection, by educating patients/parents on the risk and the recommended precautions cure, it is imperative that diagnosis and treatment of this population is not overlooked. This is especially true in rare cases of children with cirrhosis or end stage liver disease secondary to HCV, as there appears to be a higher risk of a severe course of COVID-19. This pandemic should not be a hindrance to continuing the goal of eradication of HCV in the pediatric population. Enhanced screening and awareness efforts and continued education of healthcare providers will improve the outcomes of HCV infection in the pediatric population”. This review may be an informative and useful document for students, clinicians and researchers a fortiori those working in pediatric or hepatology field. However we have some observations to make: The authors noticed in Page 6-13: 1. “Introduction”: you noticed “Non- , Non-B Hepatitis”. I think that you omitted the “A” related to hepatitis A. You should write Non-A,….”. 2. “Epidemiology”: you noticed “All 6 HCV genotypes…”. However, to date 8 genotypes are identified for HCV. 3. “Natural history”: “Albeit uncommon, progression to cirrhosis has been described and…”. This sentence may be reformulated for better readability and comprehension. 4. “Improving the cascade or care”: ”KHAMP has trained primary care providers on HCV epidemiology, diagnosis, management…”. This sentence may be reformulated, because the word "management" means prevention, diagnosis, treatment and monitoring or follow up. 5. “Conclusion”: “…a major impact on health care outcomes for patients of all ages…including…”. In this sentence "...including" may be replaced by "a fortiori". "
Rogers ME, Balistreri WF. Cascade of care for children and adolescents with chronic hepatitis C. World J Gastroenterol 2021; 27(12): 1117-1131 [PMID: 33828389 DOI: 10.3748/wjg.v27.i12.1117]
6
"The case report provided new aspect of re-treatment with NSCLC patients who developed resistance to EGFR-TKIs, and inspired the clinician to manage the difficult condition."
Hu XY, Fei YC, Zhou WC, Zhu JM, Lv DL. Triple administration of osimertinib followed by chemotherapy for advanced lung adenocarcinoma: A case report. World J Clin Cases 2021; 9(11): 2627-2633 [DOI: 10.12998/wjcc.v9.i11.2627]
7
"The procedure is interesting. The used of endoprosthesis with giant cell tumor of bone with limited resection of tumor. The concerning point may be recurrence of tumor after limited resection to keep soft tissue reconstruction."
Wang J, Zhou Y, Wang YT, Min L, Zhang YQ, Lu MX, Tang F, Luo Y, Zhang YH, Zhang XL, Tu CQ. Three-dimensional-printed custom-made patellar endoprosthesis for recurrent giant cell tumor of the patella: A case report and review of the literature. World J Clin Cases 2021; 9(11): 2524-2532 [DOI: 10.12998/wjcc.v9.i11.2524]
8
"It's very good."
Joseph DF, Li E, Stanley III SL, Zhu YC, Li XN, Yang J, Ottaviano LF, Bucobo JC, Buscaglia JM, Miller JD, Veluvolu R, Follen M, Grossman EB. Impact of type 2 diabetes on adenoma detection in screening colonoscopies performed in disparate populations. World J Clin Cases 2021; 9(11): 2433-2445 [DOI: 10.12998/wjcc.v9.i11.2433]
9
"Intersting paper "
Wang Q, Niu XY, Feng H, Wu J, Gao W, Zhang ZX, Zou YW, Zhang BY, Wang HJ. Gastrointestinal-type chemotherapy prolongs survival in an atypical primary ovarian mucinous carcinoma: A case report. World J Clin Cases 2021; 9(11): 2533-2541 [DOI: 10.12998/wjcc.v9.i11.2533]
10
"Very Interesting paper and provide novel data."
Fan JZ, Wang GF, Cheng XB, Dong ZH, Chen X, Deng YJ, Song X. Relationship between mismatch repair protein, RAS, BRAF, PIK3CA gene expression and clinicopathological characteristics in elderly colorectal cancer patients. World J Clin Cases 2021; 9(11): 2458-2468 [DOI: 10.12998/wjcc.v9.i11.2458]
11
"This manuscript is a good collection of results that aim to determine the impact of hyper-transfusion on long term survival in pediatric living donor liver transplantation. Overall, the information are well collected. However, there are some important issues I would like to emphasize. 1. Method: The authors need to clarify what is (are) the primary outcomes of the study and what are the secondary outcomes of the study. The other minor findings can be described in the results but the discussion should be based on the outcomes of interest. 2. Results: Since hyper-transfusion may be the cause of an excess ten year mortality or an epiphenomenon (difficult patients, difficult medical care etc), the authors need to perform additional competing risk analysis to define the impact of hyper-transfusion on the ten year patient survival. As to the result, hyper-transfusion is significantly associated with 30 day reoperation and 30 day excess mortality, this factor need to be consider as a competing risk for long term survival. In addition, the impact of other set of risk factors should be analyzed for the association with ten year survival. 3. Discussion: Need to be reorganized according to the revised method and results. 4. The impact of hyper-transfusion on the outcome of pediatric living donor transplantation should be clearly stated. 5. Tables 3 and 5 . The information can be limited to what are related with the potential adverse events of hyper-transfusion on the primary and secondary outcomes. "
Gordon K, Figueira ERR, Rocha-Filho JA, Mondadori LA, Joaquim EHG, Seda-Neto J, da Fonseca EA, Pugliese RPS, Vintimilla AM, Auler Jr JOC, Carmona MJC, D'Alburquerque LAC. Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation. World J Gastroenterol 2021; 27(12): 1161-1181 [PMID: 33828392 DOI: 10.3748/wjg.v27.i12.1161]
12
"Letter to editor: The World Health Organization (WHO) reported that the total number of people currently infected with HCV was approximately 185 million. Compared with adults, children and adolescents are more insidious in HCV infection, which is a public health issue that deserves great attention[1]. The estimated prevalence of HCV infection in children and adolescents is 0.15% globally, corresponding to 3.5 million patients (95% CI 3.1-3.9 million)[2]. Rogers et al comprehensively summarized the current status of HCV infection, clinical treatment strategies, clinical outcomes, diagnosis and screening in children and adolescents and point out the focus of the prevention and control of HCV to achieve the WHO goal of eliminating hepatitis in the future. For the epidemiology of HCV, this review indicated that the prevalence of HCV is increasing year by year in children and adolescents, while it is decreasing in adults. In developing countries with large populations, children’s health care was very worrying, and the prevention and treatment of HCV was even more severe, the prevalence of HCV among street children in Iran was found to be at 2.4% (95% CI: 1.8-3.3)[3]. Although vertical transmission is now the main route of HCV transmission among children and adolescents, in developing countries children who need special medical treatment, such as surgical resection, hemodialysis, and kidney transplantation, suffering higher risk of get HCV infection[4][5]. In addition, as injecting drug use becomes more and more common among children and adolescents, the risk of get HCV infection is gradually increasing. Before the 1990s, children were infected with HCV mainly through blood, blood products, or organ transplantation. Since the implementation of HCV screening of blood donors in various countries in 1992, vertical transmission has become the most important way for children to contract HCV. Although the spontaneous clearance rate of HCV through vertical transmission in children and adolescents was higher than that in adults, Modin et al reported liver disease developed in 32% of patients at a median of 33 years, the incidence of hepatocellular carcinoma was 5%, liver transplant 4% and death occurred in 3%[6]. It is worth that advanced liver disease and decompensated cirrhosis had been identified in children as young as 3 years old and as early as 1 year after infection.[7, 8] At present, the diagnosis of hepatitis C can be achieved through HCV antibody detection and HCV-RNA detection, but the status of patient’s liver damage cannot be grasped. Although the guidelines have not formally recommended the use of non-invasive methods for grading necroinflammatory activity and staging of fibrosis in routine clinical practice in children and adolescents, it can be considered for use before completing performance studies[9, 10]. In terms of treatment, the author comprehensively summarized the application status of direct-acting antiviral regimens in children and adolescents, including the therapeutic effects of different HCV gene types. However, among children and adolescents with HCV, there may be cases of receiving long-term dialysis and for the treatment of the above special populations, special attention should be paid to the possible toxic side effects of drugs. Since direct-acting antiviral regimens were not approved for HCV infected people younger than 18 years old until 2017, the prevention and treatment of HCV in children and adolescents has not received sufficient attention as in adults. Moreover, the focus of the global hepatitis has been on treatment and prevention among adult population, which bears the greatest burden of HCV. However, to realize the goal of eliminating HCV infection, all affected populations, including children and adolescents, should be taken seriously. There was still much work to be done in the prevention of HCV in children and adolescents. On the one hand, there is an urgent need to strengthen sexual education for teenagers and children and avoid drug use. On the other hand, clinical experimental research on the treatment of HCV in pregnant women should be accelerated to minimize the risk of vertical transmission. References: 1 Guidelines for the Screening Care and Treatment of Persons with Chronic Hepatitis C Infection: Updated Version. Geneva: World Health Organization, 2016. 2 Indolfi G, Easterbrook P, Dusheiko G, El-Sayed MH, Jonas MM, Thorne C, Bulterys M, Siberry G, Walsh N, Chang MH, Meyers T, Giaquinto C, Wirth S, Chan PL, Penazzato M. Hepatitis C virus infection in children and adolescents. Lancet Gastroenterol Hepatol 2019 2019-06-01; 4(6): 477-487. 3 Behzadifar M, Gorji HA, Rezapour A, Bragazzi NL. Prevalence of hepatitis C virus among street children in Iran. INFECT DIS POVERTY 2018 2018-10-01; 7(1): 88. 4 Ahmadi SM, Raeessi N. Assessing the prevalence of HBV and HCV infections in children under going hemodialysis and the related risk factors in a children's Medical Center: PS132. Porto Biomed J 2017 2017-09-01; 2(5): 236. 5 Seerat I, Mushtaq H, Rafiq M, Nadir A. Frequency and Associated Risk Factors of Hepatitis B Virus and Hepatitis C Virus Infections in Children at a Hepatitis Prevention and Treatment Clinic in Lahore, Pakistan. Cureus 2020 2020-05-02; 12(5): e7926. 6 Modin L, Arshad A, Wilkes B, Benselin J, Lloyd C, Irving WL, Kelly DA. Epidemiology and natural history of hepatitis C virus infection among children and young people. J HEPATOL 2019 2019-03-01; 70(3): 371-378. 7 Guido M, Bortolotti F, Leandro G, Jara P, Hierro L, Larrauri J, Barbera C, Giacchino R, Zancan L, Balli F, Crivellaro C, Cristina E, Pucci A, Rugge M. Fibrosis in chronic hepatitis C acquired in infancy: is it only a matter of time? AM J GASTROENTEROL 2003 2003-03-01; 98(3): 660-663. 8 Rumbo C, Fawaz RL, Emre SH, Suchy FJ, Kerkar N, Morotti RA, Shneider BL. Hepatitis C in children: a quaternary referral center perspective. J Pediatr Gastroenterol Nutr 2006 2006-08-01; 43(2): 209-216. 9 Fitzpatrick E, Quaglia A, Vimalesvaran S, Basso MS, Dhawan A. Transient elastography is a useful noninvasive tool for the evaluation of fibrosis in paediatric chronic liver disease. J Pediatr Gastroenterol Nutr 2013 2013-01-01; 56(1): 72-76. 10 Lee CK, Perez-Atayde AR, Mitchell PD, Raza R, Afdhal NH, Jonas MM. Serum biomarkers and transient elastography as predictors of advanced liver fibrosis in a United States cohort: the Boston children's hospital experience. J Pediatr 2013 2013-10-01; 163(4): 1058-1064. "
Rogers ME, Balistreri WF. Cascade of care for children and adolescents with chronic hepatitis C. World J Gastroenterol 2021; 27(12): 1117-1131 [PMID: 33828389 DOI: 10.3748/wjg.v27.i12.1117]
13
"The review was very informative for a non-expert and recapitulated many aspects of interest, covering updated progress and additional challenges that need to be overcome. Section 1&2: Introduction/ Brief summary of autoimmunity in T1DM The authors should have merged the first two sections after the abstract. The review would flow better, if the second main section (Brief summary of autoiimunity in T1DM) came after the first paragraph of the first section (Introduction). Particularly, because the authors finish the former with the message of the Β islet destruction and in the second paragraph of th eintroduction they explain adequately how this challenge can be surpassed. Section 3: Defects of current T1DM treatment I think it would be interesting if the authors referenced in the second paragraph reviews on a) selection of encapsulation materials and transplantation site, b)improve immune regulation and c) blood vessel formation Moreover, since the following sections focus significantly on key transcription factors for stem cell differentiation, the authors could have made a more compelling case about their importance in this paragraph. ANother key point I would like to address is that I always find interesting the 'prevent autoimmune destruction' concept, since in many cases, the damage is irreversible at the time of diagnosis. Therefore, the authors should have addressed here, providing more literature, the two other options, which are induced regeneration from MSCs or their differentiation to Β-islet. Despite the focus on the latter in the following sections, if this contrast would have been explicitly explained and contrasted at this point, the readers would assimilate easier the greater image of the clinical bottlenecks of possible T1DM treatments. Section 4: Maturation process of Β cells in vivo This chapter feels a bit misleading from the title, since it mostly focuses on the islet development steps during the embryonic development, in mice or humans. Plus, many aspects of this paragraph are informative, yet do not correlate significantly with the follow-up section, of how the maturaiton actually occurs. Thus, most of the points raised in this paragraph can be overlooked and forgotten from the reader, thus weakening the overall view on the paper. The most relevant aspect described is the MAF transcription factor and a few others which are introduced later, however the major aspect of the chapter is very introductory and based on the paper title, could be reduced. Section 5: Key markers in the process of β-cell maturation This part was very detailed and elaborate, with lots of evidence and body of work done previously, which do not come by as superficial information. What could have made the whole paragraph to read, would have been to split it in at least two or three subsections, underlying a wider message across each, since it comprises of numeorus factors that affect β cell maturation Section 6: Induction of β cells in vitro and current problems This is also a very well-written paragraph touching upon many crucial prerequisites in testing methods to produce effectively β cells, such as prolonged and sustainable insulin release, autocrine regulation of Β cells by other pancreatic islet cell types, culture techniques based on nutrition, maturation, and TF delivery. "
Sun ZY, Yu TY, Jiang FX, Wang W. Functional maturation of immature β cells: A roadblock for stem cell therapy for type 1 diabetes. World J Stem Cells 2021; 13(3): 193-207 [PMID: 33815669 DOI: 10.4252/wjsc.v13.i3.193]
14
"Malignant melanoma most often occurs in the skin. Intraspinal malignant melanoma is quite rare. It is mainly distributed in the cervical segment, followed by the thoracic segment and thoracolumbar junction segment. This study analyzed and discussed the clinical, pathological, imaging data and treatment of this case of lumbar melanoma. The MRI features of melanoma vary with the proportion of melanocytes in the tumor.The diagnosis of this disease depends on puncture or surgical pathology.Because malignant melanoma in spinal canal is very rare, and its imaging manifestations are variable, it mainly needs to be differentiated from schwannoma and meningioma in spinal canal. In addition, hemorrhagic malignant melanoma should be differentiated from epidural hematoma and lipoma. For other rare intramedullary spinal cord tumors in this group, careful separation along the tumor interface is also required during microsurgical resection.However, it is often difficult to completely remove the tumor during the operation. The use of high-power microscope and ultrasonic scalpel is helpful to completely remove the tumor, and greatly improves the safety of the operation.For high-grade malignant tumors, excessive resection should not be pursued when the peritumoral interface is unclear. Postoperative radiotherapy or targeted therapy or immunotherapy based on gene detection can be considered to prolong the disease-free survival or overall survival rate. Neurophysiological monitoring and intraoperative ultrasound accurate positioning have become one of the routine intraoperative auxiliary means in neurosurgery. It is of great significance to guide accurate tumor resection, avoid spinal cord injury and improve postoperative neurological function."
Li XJ, Yang L, Yan XF, Zhan CT, Liu JH. Granulomatosis with polyangiitis presenting as high fever with diffuse alveolar hemorrhage and otitis media: A case report. World J Clin Cases 2021; 9(10): 2344-2351 [DOI: 10.12998/wjcc.v9.i10.2344]
15
"a well-done review"
Marques HS, Araújo GRL, da Silva FAF, de Brito BB, Versiani PVD, Caires JS, Milet TC, de Melo FF. Tertiary peritonitis: A disease that should not be ignored. World J Clin Cases 2021; 9(10): 2160-2169 [DOI: 10.12998/wjcc.v9.i10.2160]
16
"Was a family history of gastric cancer part of the exclusion criteria? can you conclude on the best candidates for additionnal surgery "
Zheng Z, Bu FD, Chen H, Yin J, Xu R, Cai J, Zhang J, Yao HW, Zhang ZT. Factors associated with overall survival in early gastric cancer patients who underwent additional surgery after endoscopic submucosal dissection. World J Clin Cases 2021; 9(10): 2192-2204 [DOI: 10.12998/wjcc.v9.i10.2192]
17
"you mentioned a questionnaire intended for patients before the colonoscopy without detailing it the 1st paragraph of the statistical analysis part describes responses definitions not the statistical analysis"
Zhang H, Liu J, Ma SL, Huang ML, Fan Y, Song M, Yang J, Zhang XX, Song QL, Gong J, Huang PX, Zhang H. Impact of simethicone on bowel cleansing during colonoscopy in Chinese patients. World J Clin Cases 2021; 9(10): 2238-2246 [DOI: 10.12998/wjcc.v9.i10.2238]
18
"There is repeated data in the clinical presentation Have you performed endoscopic checks and follow-up imaging Details of histological examinations should be described in the clinical presentation section. Is there an interest in performing a systematic endoscopy in order to make the diagnosis of gastric cancer at an early stage and Can you propose a monitoring algorithm for these patients including CA19-9, imaging and endoscopy?"
Ma YH, Yamaguchi T, Yasumura T, Kuno T, Kobayashi S, Yoshida T, Ishida T, Ishida Y, Takaoka S, Fan JL, Enomoto N. Pancreatic cancer secondary to intraductal papillary mucinous neoplasm with collision between gastric cancer and B-cell lymphoma: A case report. World J Clin Cases 2021; 9(10): 2400-2408 [DOI: 10.12998/wjcc.v9.i10.2400]
19
"I would like to thank the editorial board for the excellent summary of the activities of the journal. I would like to suggest one point; as board member I am having trouble in receiving communicatory mail from the journal website. Therefore, I have missed a review request. Could there be anything done about it?"
Ma L, Li X. Meeting report of the editorial board meeting for World Journal of Hepatology 2021. World J Hepatol 2021; 13(2): 162-165 [PMID: 33708348 DOI: 10.4254/wjh.v13.i2.162]
20
"It's a great report. Are you sure if the waterfall sign will appear in other similar patient? In my opinion, I agree to explore this sign in advanced"
Xing ZX, Yang H, Zhang W, Wang Y, Wang CS, Chen T, Chen HJ. Point-of-care ultrasound for the early diagnosis of emphysematous pyelonephritis: A case report and literature review . World J Clin Cases 2021; 9(11): 2584-2594 [DOI: 10.12998/wjcc.v9.i11.2584]
52 items  Read more >>
Write to the Help Desk
  • ALL AUTHOR RESOURCES
  • Article Processing Charge
  • Common Usage of Quantities and Units
  • Copyright License Agreement
  • Create an Account
  • Criteria for Authorship
  • Guidelines for Authors
  • Guidelines for Manuscript Type and Related Ethics Documents
  • Guidelines for the Manuscript Publishing Process
  • Journals
  • Language Editing Process for Manuscripts Submitted by Non-Native Speakers of English
  • Open-Access
  • Publication Misconduct
  • Quality of Publications
  • Steps for Submitting Manuscripts
  • Submit a Manuscript
  • ALL PEER-REVIEWER RESOURCES
  • Peer-Review Process
  • Peer-Reviewer Tracking for Manuscripts
  • Reviewer Acknowledgment
  • MEMBERSHIP
  • Association of Learned and Professional Society Publishers (ALPSP)
  • Committee on Publication Ethics (COPE)
  • CrossRef
  • International Association of Scientific, Technical & Medical Publishers (STM)
  • Open Access Scholarly Publishers Association (OASPA)
  • ALL PUBLISHER RESOURCES
  • About the BPG
  • BPG Home
  • Committee on Publication Ethics
  • Company Registration
  • Contact Us
  • Editorial Office
  • ICMJE Conformity
  • Management Team
  • Ownership
  • Permissions
  • Privacy Policy
  • Publisher
  • Publishing Credentials
  • Revenue Sources
  • Special Statement
  • Terms of Use
© 2004-2021 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

California Corporate Number: 3537345