Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Transl Med. Nov 28, 2026; 12(4): 126251
Published online Nov 28, 2026. doi: 10.5528/wjtm.126251
Published online Nov 28, 2026. doi: 10.5528/wjtm.126251
Advances in deep inspiration breath-hold technique for radiotherapy of right-sided breast cancer
Wan-Yi Chen, Liang Yi, Department of Oncology, Yueyang Hospital Affiliated to Hunan Normal University, Yueyang 414000, Hunan Province, China
Wan-Yi Chen, Yueyang Hospital Affiliated to Hunan Normal University, Hunan Normal University, Yueyang 414000, Hunan Province, China
Zi-Yang Gan, Yu-Wei Cai, Zhi-Qiang Hua, Liang Yi, Radiation Therapy Center, Yueyang Hospital Affiliated to Hunan Normal University, Yueyang 414000, Hunan Province, China
Author contributions: Chen WY and Yi L designed the research study; Chen WY, Gan ZY, Cai YW, and Hua ZQ performed the literature search and data extraction; Chen WY and Yi L analyzed and interpreted the data; Chen WY drafted the original manuscript; Yi L reviewed and edited the manuscript; and all authors have read and approved the final version.
AI contribution statement: In accordance with the artificial intelligence (AI) Tool Usage Policy of World Journal of Translational Medicine, the authors disclose the following use of AI tools during manuscript preparation. The authors take full responsibility and accountability for all content of this manuscript, including any portions for which AI tools were used as assistive technologies. All AI-assisted outputs were carefully reviewed, validated, and approved by the authors. AI tools were not used to generate original scientific data, perform independent scientific analyses, or draw scientific conclusions. (1) DeepSeek (AI language model, DeepSeek Inc.): Used for language editing and proofreading, including English-to-Chinese and Chinese-to-English translation assistance, language polishing, grammar correction, logical verification, and wording optimization. The use of this tool was limited to linguistic refinement and did not extend to generating scientific content, research data, or analytical conclusions; and (2) Minmo (AI-assisted coding assistant): Used to assist in writing and executing R code for generating Figure 1 (deep inspiration breath-hold clinical implementation workflow diagram). The tool assisted in code development and figure output; the conceptual design, clinical workflow logic, and final figure content were determined entirely by the authors. The manuscript text, core scientific viewpoints, research content, literature analysis, and scholarly interpretation are the original work of the authors.
Supported by the China Science Exchange Foundation (Biomedical Innovation and Development Technology Public Welfare Project), No. SWYY2026002205.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
Corresponding author: Liang Yi, MD, Department of Oncology, Yueyang Hospital Affiliated to Hunan Normal University, No. 263 Baling East Road, Yueyang 414000, Hunan Province, China. yiliangjs@126.com
Received: July 29, 2026
Revised: August 23, 2026
Accepted: October 9, 2026
Published online: November 28, 2026
Processing time: 98 Days and 12 Hours
Revised: August 23, 2026
Accepted: October 9, 2026
Published online: November 28, 2026
Processing time: 98 Days and 12 Hours
Core Tip
Core Tip: Deep inspiration breath-hold (DIBH) is well known for shielding the heart and lung during left-sided breast radiotherapy, but whether it helps right-sided patients remains unclear. For right-sided tumors, the main organs at risk include the lung on the same side, the liver, the heart, the right coronary artery, and the breast on the opposite side. Current data show that breath-hold can cut doses to the right lung and liver, yet it does not seem to spare the heart or the contralateral breast much. In practice, DIBH is mostly delivered with real-time position management or optical surface monitoring; active breathing control is rarely used in this context. More research is needed going forward.