Review
Copyright ©The Author(s) 2017.
World J Nephrol. May 6, 2017; 6(3): 111-118
Published online May 6, 2017. doi: 10.5527/wjn.v6.i3.111
Table 1 Summary of cannabinoid signaling on modulation of diseases with increased oxidative stress
DiseaseSpeciesDisease modelRef.
Diabetes mellitus
Microvascular complications
NephropathyMouseIn vivo[49,50]
RetinopathyMouse, ratIn vivo[43,44]
NeuropathyMouse, ratIn vivo[45-47]
Macrovascular complicationsMouse, ratIn vivo[40,41]
Cardiomyopathy
Diabetic cardiomyopathyMouseIn vivo[57]
Human cardiomyocyteIn vitro[57]
Myocardial ischemia/reperfusionMouseIn vivo[51,53,54]
Ageing-related cardiomyopathyMouseIn vivo[55]
Doxorubicin-induced cardiomyopathyMouseIn vivo[52,56]
Human cardiomyocyteIn vitro[56]
Rat cardiomyocyteIn vitro[52]
Cisplatin nephropathyMouseIn vivo[68,69]
Liver injury/fibrosis
Ischemia/reperfusion hepatocyte injuryMouseIn vivo[59]
CCl4-induced hepatocyte injuryMouseIn vivo[59]
Alcoholic liver fibrosisMouseIn vivo[62]
Fibrotic activation of hepatic stellate cellsHuman, rat, mouseIn vitro[58,60,63,64]
Biliary diseases
CholangiopathiesMouseIn vivo[65]
Mouse cholangiocyteIn vitro[65]
Enteric diseases
Inflammatory bowel diseaseMouseIn vivo[66]
ColitisMouseIn vivo[67]
Autoimmune systemic sclerosisMouseIn vivo[70]