Copyright ©The Author(s) 2015.
World J Nephrol. Feb 6, 2015; 4(1): 57-73
Published online Feb 6, 2015. doi: 10.5527/wjn.v4.i1.57
Table 3 Utility of new biomarkers in chronic kidney disease
BiomarkerOriginOutcome assessed
Urinary liver-type fatty acid-binding proteinProximal tubuleDiabetic Nephropathy: Microalbuminuria and mortality
Urinary N-Acetyl-b-O-glucosaminidaseProximal tubuleDiabetic Nephropathy: Albuminuria
Urinary connective tissue growth factorProximal tubuleDiabetic Nephropathy: Glomerular filtration rate decline
Interleukin-18TubulointerstitialDiabetic Nephropathy: Albuminuria
Apolipoprotein A-IVIntestinal enterocytesCKD: CKD Progression
Urinary CD14 mononuclear cellsPolycystic kidney disease: Kidney volume
Neutrophil gelatinase associated lipocalinProximal and distal tubuleGlomerulonephritis: GFR and proteinuria CKD: CKD progression, renal replacement therapy and mortality
Kidney injury molecule-1Proximal tubuleCKD: CKD progression and renal replacement therapy
Fibroblast growth factor-23Osteocytes and osteoblastsDiabetic Nephropathy and others CKD: CKD progression and mortality
Urinary retinol binding protein 4Proximal tubuleCongenital or acquired tubular dysfunction: Proximal tubule dysfunction