Copyright ©The Author(s) 2015.
World J Nephrol. May 6, 2015; 4(2): 245-253
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.245
Figure 1
Figure 1 Hypogonadism therapeutic hormones and mechanism of action. Exogenous T and anabolic steroids negatively affect the HPG axis. SERMs such as CC stop the negative feedback of estrogen on the HPG axis. hCG stimulates Leydig cells. Aromatase inhibitors inhibit the conversion of T to E. LH: Luteinizing hormone; FSH: Follicle-stimulating hormone; AAS: Anabolic-Androgenic steroid; hCG: Human chorionic gonadotropin; GnRH: Gonadotropin-releasing hormone.