Retrospective Cohort Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Nov 6, 2016; 5(6): 497-506
Published online Nov 6, 2016. doi: 10.5527/wjn.v5.i6.497
Outcomes of renal transplant recipients with BK virus infection and BK virus surveillance in the Auckland region from 2006 to 2012
Chun-Yuan Hsiao, Helen L Pilmore, Lifeng Zhou, Janak R de Zoysa
Chun-Yuan Hsiao, Department of Renal Medicine, Middlemore Hospital, Counties Manukau District Health Board, Auckland 1640, New Zealand
Helen L Pilmore, Department of Renal Medicine, Auckland District Health Board, Auckland 1142, New Zealand
Helen L Pilmore, the University of Auckland, Auckland 1010, New Zealand
Lifeng Zhou, Planning, Funding and Outcomes Unit, Waitemata and Auckland District Health Boards, Auckland 0740, New Zealand
Janak R de Zoysa, Department of Renal Medicine, North Shore Hospital, Waitemata District Health Board, Auckland 0740, New Zealand
Janak R de Zoysa, Waitemata Clinical School, the University of Auckland, Auckland 0740, New Zealand
Author contributions: Hsiao CY performed the study design, data collection and analysis, statistics and writing of the manuscript; Pilmore HL performed study design, assistance in performing the study and revision of the manuscript; Zhou L provided advice on biostatistics and revision of the manuscript; de Zoysa JR performed study design, assistance in performing the study and revision of the manuscript.
Institutional review board statement: This retrospective review was approved by the Northern X Regional Ethics Committee (NTX/EXP).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous, de-identified clinical data.
Conflict-of-interest statement: There are no conflicts of interest in the publication of this paper.
Data sharing statement: The original de-identified dataset is available on request from the corresponding author at chunyuan.hsiao@middlemore.co.nz.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Chun-Yuan Hsiao, FRACP, Physician and Nephrologist, Department of Renal Medicine, Middlemore Hospital, Counties Manukau District Health Board, Private Bag 93311, Otahuhu, Auckland 1640, New Zealand. chunyuan.hsiao@middlemore.co.nz
Telephone: +64-9-2760000
Received: May 25, 2016
Peer-review started: May 26, 2016
First decision: June 17, 2016
Revised: August 8, 2016
Accepted: August 27, 2016
Article in press: August 29, 2016
Published online: November 6, 2016
Core Tip

Core tip: A retrospective analysis of 226 patients from Auckland, New Zealand found BK polyomavirus (BKV) as an uncommon cause of graft loss. Renal units without a formal BKV surveillance programme showed a similar incidence and outcomes for BK polyomavirus nephropathy (BKVN) to centres with an active screening programme. When designing a cost effective screening programme for BKV infection, it should be centre specific in relation to the units immunosuppression and monitoring protocol, epidemiology and outcomes of BKVN.