Copyright
©2016 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Nephrol. Mar 6, 2016; 5(2): 182-188
Published online Mar 6, 2016. doi: 10.5527/wjn.v5.i2.182
Published online Mar 6, 2016. doi: 10.5527/wjn.v5.i2.182
Sentinel lymph node biopsy in renal malignancy: The past, present and future
Tharani Mahesan, Alberto Coscione, Ben Ayres, Nick Watkin, Department of Urology, St George’s Hospital, London SW17 0QT, United Kingdom
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Nick Watkin, Consultant Urologist, Department of Urology, St George’s Hospital, Blackshaw Road, Tooting, London SW17 0QT, United Kingdom. nick.watkin@stgeorges.nhs.uk
Telephone: +44-208-6721255 Fax: +44-208-4876304
Received: August 22, 2015
Peer-review started: August 25, 2015
First decision: October 30, 2015
Revised: December 19, 2015
Accepted: January 8, 2016
Article in press: January 11, 2016
Published online: March 6, 2016
Peer-review started: August 25, 2015
First decision: October 30, 2015
Revised: December 19, 2015
Accepted: January 8, 2016
Article in press: January 11, 2016
Published online: March 6, 2016
Core Tip
Core tip: A number of studies have examined the use of sentinel lymph node biopsy in urogenital malignancies. In penile and prostate cancer it has been found to be a valuable tool to aid staging and accurately predict prognosis. Its use in renal cancer is poorly explored and would benefit from a better understanding of the lymphatic drainage of the kidney. It is also proposed that modifications of the technique such as use of positron emission tomography/computed tomography scanning and near infra-red fluorescence optical imaging agents may further improve the technique making it a feasible option for use in renal malignancy.