Published online Nov 6, 2015. doi: 10.5527/wjn.v4.i5.492
Peer-review started: July 8, 2014
First decision: August 14, 2014
Revised: August 24, 2015
Accepted: September 1, 2015
Article in press: September 2, 2015
Published online: November 6, 2015
Core tip: Nephrolithiasis is a serious problem for both patients and the health system. Recurrence stands out as a significant problem in urinary system stone disease, the prevalence of which is increasing gradually. While classical therapeutic options are available for all stone types, the number of randomized controlled studies and extensive meta-analyses focusing on their efficiency are inadequate. Various alternative therapeutic options to these medical therapies also stand out in recent years. This review focuses briefly on classical medical therapy, along with alternative options, related diets, and medical expulsive therapy.