Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.277
Peer-review started: June 29, 2014
First decision: August 14, 2014
Revised: December 29, 2014
Accepted: January 30, 2015
Article in press: February 2, 2015
Published online: May 6, 2015
Core tip: Hepatorenal syndrome (HRS) is a severe complication of chronic liver diseases and is usually associated with a poor prognosis. It is not a renal disease but a renal dysfunction that develops as a result of a systemic condition associated with liver failure. To prevent HRS by taking some preventive measures is possible and although the definitive treatment is liver transplantation, a rapid diagnosis and prompt initiation of the treatment leads to an important improvement in the prognosis. In this review, we cover the physiopathology, diagnosis and treatment options of HRS.