Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. May 6, 2015; 4(2): 277-286
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.277
Management of hepatorenal syndrome
Halit Ziya Dundar, Tuncay Yılmazlar
Halit Ziya Dundar, Tuncay Yılmazlar, Department of General Surgery, Faculty of Medicine, Uludag University, Gorukle, 16285 Bursa, Turkey
Author contributions: Both authors contributed to this manuscript.
Conflict-of-interest: The authors declare no conflicts of interest regarding this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Halit Ziya Dundar, MD, Department of General Surgery, Faculty of Medicine, Uludag University, Gorukle, 16285 Bursa, Turkey.
Telephone: +90-224-2952040 Fax: +90-224-4428398
Received: June 29, 2014
Peer-review started: June 29, 2014
First decision: August 14, 2014
Revised: December 29, 2014
Accepted: January 30, 2015
Article in press: February 2, 2015
Published online: May 6, 2015
Core Tip

Core tip: Hepatorenal syndrome (HRS) is a severe complication of chronic liver diseases and is usually associated with a poor prognosis. It is not a renal disease but a renal dysfunction that develops as a result of a systemic condition associated with liver failure. To prevent HRS by taking some preventive measures is possible and although the definitive treatment is liver transplantation, a rapid diagnosis and prompt initiation of the treatment leads to an important improvement in the prognosis. In this review, we cover the physiopathology, diagnosis and treatment options of HRS.