Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.263
Peer-review started: November 29, 2014
First decision: December 12, 2014
Revised: December 22, 2014
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: May 6, 2015
Core tip: Primary glomerular diseases in the elderly population are a frustrating topic due to difficulties in both diagnosis and treatment. The most frequent type of primary glomerular disease and the most frequent cause of nephrotic syndrome is membranous nephropathy. The frequency of pauci-immune glomerulonephritides increases considerably in the very elderly population. Renal biopsy is the inevitable diagnostic method in the elderly as in all other age groups. The decision about adding immune suppressive therapies to conservative methods should be made considering many factors like co-morbidities, drug side effects, patient preference, life expectancy and renal functions at the time of diagnosis.