Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Immune profiling and cancer post transplantation
Christopher Martin Hope, Patrick Toby H Coates, Robert Peter Carroll, Centre for Clinical and Experimental Transplantation, Central Northern Adelaide Renal and Transplantation Services, Adelaide SA 5000, Australia
Christopher Martin Hope, Patrick Toby H Coates, Robert Peter Carroll, Department of Medicine, the University of Adelaide, Adelaide SA 5000, Australia
Christopher Martin Hope, Central Northern Adelaide Renal and Transplant Services, Renal Lab, IMVS building, Royal Adelaide Hospital, Adelaide SA 5000, Australia
Author contributions: Hope CM planned, wrote and edited manuscript; Coates PTH critically revised and edited manuscript and Carroll RP organised, planned, co-wrote and edited manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Christopher Martin Hope, PhD, Central Northern Adelaide Renal and Transplant Services, Renal Lab, IMVS building, Royal Adelaide Hospital, North Terrace, Adelaide SA 5000, Australia. christopher.hope@health.sa.gov.au
Telephone: +61-8-82220976 Fax: +61-8-82220987
Received: July 11, 2014
Peer-review started: July 12, 2014
First decision: October 14, 2014
Revised: November 3, 2014
Accepted: November 7, 2014
Article in press: November 10, 2014
Published online: February 6, 2015
Peer-review started: July 12, 2014
First decision: October 14, 2014
Revised: November 3, 2014
Accepted: November 7, 2014
Article in press: November 10, 2014
Published online: February 6, 2015
Core Tip
Core tip: Kidney transplant recipients (KTR) with cancer have different leukocyte compartmentalisations and immune cell functions than KTR with no cancer. These differences can be used to determine KTR at risk of developing cancer and identify those who do not mount a reaction to their graft. Indicating there is a group of KTR that may benefit from pharmacological immunosuppressive drug dose reductions.