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Role of endoscopic ultrasound fine-needle aspiration evaluating adrenal gland enlargement or mass
Melissa Martinez, Julia LeBlanc, Mohammad Al-Haddad, Stuart Sherman, John DeWitt, Department of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN 46202, United States
Author contributions: Martinez M and DeWitt J contributed equally to this work, abstracted data from medical records and analyzed data; Martinez M, DeWitt J, Al-Haddad M, Sherman S and LeBlanc J wrote the paper.
Correspondence to: John DeWitt MD, FASGE, FACG, Associate Professor of Medicine, Department of Gastroenterology and Hepatology, Indiana University School of Medicine, 550 North University Blvd, UH 4100, Indianapolis, IN 46202, United States. jodewitt@iu.edu
Telephone: +1-317-9441113 Fax: +1-317-2781949
Received: December 4, 2013
Revised: February 18, 2014
Accepted: May 8, 2014
Published online: August 6, 2014
Revised: February 18, 2014
Accepted: May 8, 2014
Published online: August 6, 2014
Core Tip
Core tip: Studies evaluating endoscopic ultrasound fine-needle aspiration (EUS-FNA) of the adrenal gland generally include patients with underlying malignancy only and most lack follow-up for benign lesions. We report the clinical utility of adrenal gland EUS-FNA in a retrospective study that included 94 patients who underwent EUS-FNA of either adrenal for various indications and provide follow-up information for those with benign EUS-FNA cytology results. For the diagnosis of malignancy, EUS-FNA of either adrenal had sensitivity, specificity, positive predictive value and negative predictive value of 86%, 97%, 96% and 89%, without serious adverse events.