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World J Nephrol. Aug 6, 2013; 2(3): 77-83
Published online Aug 6, 2013. doi: 10.5527/wjn.v2.i3.77
Evaluation of microvascular reactivity with laser Doppler flowmetry in chronic kidney disease
Levente Babos, Zoltán Járai, János Nemcsik
Levente Babos, János Nemcsik, Department of Family Medicine, Semmelweis University, 1125 Budapest, Hungary
Zoltán Járai, Department of Cardiology, St. Imre Teaching Hospital, 1115 Budapest, Hungary
Author contributions: Babos L solely contributed to this paper; Járai Z and Nemcsik J revised it critically for important intellectual content.
Correspondence to: János Nemcsik MD, PhD, Department of Family Medicine, Semmelweis University, Kútvölgyi str. 4, 1125 Budapest, Hungary.
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Received: June 13, 2013
Revised: July 31, 2013
Accepted: August 2, 2013
Published online: August 6, 2013
Core Tip

Core tip: Atherosclerotic diseases are the leading causes of death in chronic kidney disease (CKD) patients. Endothelial dysfunction is an important initial step of atherosclerotic processes, so with the early diagnosis and treatment of endothelial dysfunction many cardiovascular events can potentially be prevented. Laser Doppler flowmetry (LDF) gives the opportunity of the non-invasive study of microcirculation and endothelial function. This review summarizes the results of different LDF techniques and their usefulness in the diagnosis of endothelial dysfunction in CKD patients.