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World J Virol. Sep 25, 2022; 11(5): 293-299
Published online Sep 25, 2022. doi: 10.5501/wjv.v11.i5.293
Rhino-orbital-cerebral mucormycosis as a complication of coronavirus disease 2019
Raid M Al-Ani
Raid M Al-Ani, Department of Surgery/Otolaryngology, University of Anbar, College of Medicine, Ramadi 31001, Anbar, Iraq
Author contributions: Raid M Al-Ani performed all aspects of this manuscript’s generation.
Conflict-of-interest statement: The author declares that there is no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Raid M Al-Ani, MBChB, Academic Research, Full Professor, Senior Editor, Surgeon, Department of Surgery/Otolaryngology, University of Anbar, College of Medicine, Al-Thaela, Ramadi 31001, Anbar, Iraq. med.raed.alani2003@uoanbar.edu.iq
Received: April 17, 2022
Peer-review started: April 17, 2022
First decision: May 12, 2022
Revised: May 13, 2022
Accepted: August 12, 2022
Article in press: August 12, 2022
Published online: September 25, 2022
Core Tip

Core Tip: Rhino-orbital-cerebral mucormycosis is an aggressive, opportunistic fungal infection. There is an increment in cases of this condition in the era of coronavirus disease 2019, particularly in India. It usually affects the severe or critical types of the COVID-19 and those with a history of diabetes mellitus, corticosteroid therapy, and mechanical ventilation. Early diagnosis with prompt treatment carries a better outcome. The treatment consists of intravenous or local amphotericin B, surgical debridement, and reversal of any immunocompromised conditions. However, this disease has a poor prognosis with a high rate of morbidity and mortality.