Published online Mar 25, 2021. doi: 10.5501/wjv.v10.i2.69
Peer-review started: November 4, 2020
First decision: December 11, 2020
Revised: December 22, 2020
Accepted: January 8, 2021
Article in press: January 8, 2021
Published online: March 25, 2021
Core Tip: North Africa is a unique geographical region located on the southern Mediterranean basin and represents the largest region of Africa. Human immunodeficiency virus (HIV) infection is an increasing threat in this region. Previous studies analyzed mainly the risk factors associated with risk groups at a national level and no single study has yet analyzed the actual epidemiological situation of HIV/acquired immunodeficiency syndrome (AIDS) in the whole region. This review aims to analyze and characterize the epidemiological and geographic variation of HIV/AIDS in North African countries and to highlight the strategies needed to combat this epidemic at the national and regional levels.