Retrospective Cohort Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Dec 25, 2023; 12(5): 272-285
Published online Dec 25, 2023. doi: 10.5501/wjv.v12.i5.272
COVID-19 frequency and clinical course in children with asthma
Muhammet Cihat Özata, Ümmügülsüm Dikici, Öner Özdemir
Muhammet Cihat Özata, Medical Faculty, Sakarya University, Adapazarı 54100, Sakarya, Türkiye
Ümmügülsüm Dikici, Öner Özdemir, Department of Pediatric Allergy and Immunology, Sakarya University, Adapazarı 54100, Sakarya, Türkiye
Author contributions: Özata MC, Dikici Ü and Özdemir Ö designed the research; Özata MC and Dikici Ü performed the research; Dikici Ü and Özdemir Ö contributed analytic tools; Özata MC and Özdemir Ö analyzed the data; Özata MC, Dikici Ü and Özdemir Ö wrote the paper.
Institutional review board statement: This study's approval was obtained from the Sakarya University Faculty of Medicine clinical research ethics committee (Decision no: E-71522473-050.01.04-128344-122).
Informed consent statement: All study participants or their legal guardians, provided informed written consent before enrollment.
Conflict-of-interest statement: The authors have no conflict to disclose.
Data sharing statement: The data supporting this study's findings are available on request from the corresponding author.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Öner Özdemir, MD, Professor, Department of Pediatric Allergy and Immunology, Sakarya University, Adnan Menderes cad, Adapazarı 54100, Sakarya, Türkiye.
Received: July 26, 2023
Peer-review started: July 26, 2023
First decision: September 4, 2023
Revised: September 13, 2023
Accepted: November 30, 2023
Article in press: November 30, 2023
Published online: December 25, 2023
Research background

Studies are ongoing as the consequences and impact of coronavirus disease 2019 (COVID-19) in children with chronic diseases such as asthma are controversial.

Research motivation

The consequences of COVID-19 in children with asthma are controversial.

Research objectives

This study aims to fill this research gap by retrospectively evaluating the course, laboratory, and clinical findings of COVID-19 among 414 asthmatic children followed up from the pediatric allergy outpatient clinic and known to have had COVID-19.

Research methods

The data of 5510 patients over the age of 5 diagnosed with asthma in our hospital's data were retrospectively scanned with certain parameters using protocol numbers from the hospital filing system.

Research results

As a result of retrospectively scanning the data of 5510 asthma patients over the age of 5, it was determined that 414 (7.5%) patients had COVID-19. The mean age of 414 patients was 17.18 ± 4.08 (min: 6; max: 28) years. 203 of our 414 patients are male, and 211 are female.

Research conclusions

According to our study, there is a correlation between the severity of COVID-19 and asthma symptoms and the course of the disease.

Research perspectives

Further investigation is needed to explore the relationship between COVID-19 and asthma, and it can be suggested that COVID-19 may trigger asthma attacks, and asthma may impact the course of COVID-19.