Retrospective Cohort Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 24, 2017; 7(3): 203-212
Published online Jun 24, 2017. doi: 10.5500/wjt.v7.i3.203
Developing a donation after cardiac death risk index for adult and pediatric liver transplantation
Shirin Elizabeth Khorsandi, Emmanouil Giorgakis, Hector Vilca-Melendez, John O’Grady, Michael Heneghan, Varuna Aluvihare, Abid Suddle, Kosh Agarwal, Krishna Menon, Andreas Prachalias, Parthi Srinivasan, Mohamed Rela, Wayel Jassem, Nigel Heaton
Shirin Elizabeth Khorsandi, Emmanouil Giorgakis, Hector Vilca-Melendez, John O’Grady, Michael Heneghan, Varuna Aluvihare, Abid Suddle, Kosh Agarwal, Krishna Menon, Andreas Prachalias, Parthi Srinivasan, Mohamed Rela, Wayel Jassem, Nigel Heaton, Institute of Liver Studies, King’s College Hospital, London SE5 9RS, United Kingdom
Author contributions: Khorsandi SE designed and wrote study; Giorgakis E performed the analysis and was involved in writing the manuscript; Vilca-Melendez H, O’Grady J, Heneghan M, Aluvihare V, Suddle A, Agarwal K, Menon K, Prachalias A, Srinivasan P, Rela M and Jassem W were all involved in the editing and review of the manuscript; Heaton N provided guidance in the manuscript composition and gave final institutional approval.
Institutional review board statement: There was institutional approval for the present work.
Conflict-of-interest statement: None of the authors have any conflict of interest declare that is applicable to the present manuscript.
Data sharing statement: No additional data is available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Nigel Heaton, Professor, Institute of Liver Studies, King’s College Hospital, London SE5 9RS, United Kingdom. nigel.heaton@nhs.net
Telephone: +44-20-32994801 Fax: +44-20-32993575
Received: November 18, 2016
Peer-review started: November 23, 2016
First decision: December 29, 2016
Revised: January 21, 2017
Accepted: March 12, 2017
Article in press: March 13, 2017
Published online: June 24, 2017
Core Tip

Core tip: Calculating the donor after cardiac death (DCD) Risk Index score using objective variables from the donor (cold ischemic time, warm ischemic time, donor hepatectomy time) and from the selected recipient (primary indication for transplant, model for end-stage liver disease, retransplantation) can help rationalize the risk of using a DCD liver in a given recipient in order to produce good results.