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World J Transplant. Sep 24, 2013; 3(3): 30-35
Published online Sep 24, 2013. doi: 10.5500/wjt.v3.i3.30
Published online Sep 24, 2013. doi: 10.5500/wjt.v3.i3.30
New developments in transplant-acquired allergies
Öner Özdemir, Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Sakarya University, Research and Training Hospital of Sakarya University, Adapazarı, 54100 Sakarya, Turkey
Author contributions: Özdemir Ö solely contributed to this paper.
Correspondence to: Öner Özdemir, MD, Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Sakarya University, Research and Training Hospital of Sakarya University, Adapazarı, 54100 Sakarya, Turkey. oner.ozdemir.md@gmail.com
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Received: April 21, 2013
Revised: May 19, 2013
Accepted: June 1, 2013
Published online: September 24, 2013
Revised: May 19, 2013
Accepted: June 1, 2013
Published online: September 24, 2013
Core Tip
Core tip: Transplant-acquired allergy (TAA) was firstly described after bone marrow transplantation and mostly observed in a transient form. Although TAA is mostly found to be associated with liver transplantation; it has been recently reported to be related with heart, intestinal, lung and even renal transplantations in adults. Most studies suggest that the functioning liver itself, and not only tacrolimus immunosuppression, is one of the main contributors to TAA in these patients. Most patients will have symptomatic improvement following reduced immunosuppression and diet. Nevertheless, recent studies suggest that allergic diseases (e.g., eczema, rhinitis and asthma) occur in some of pediatric transplant recipients.