Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Aug 18, 2022; 12(8): 259-267
Published online Aug 18, 2022. doi: 10.5500/wjt.v12.i8.259
Trends and outcomes of liver transplantation among older recipients in the United States
Kenji Okumura, Joon Sub Lee, Abhay Dhand, Hiroshi Sogawa, Gregory Veillette, Devon John, Ryosuke Misawa, Roxana Bodin, David C Wolf, Thomas Diflo, Seigo Nishida
Kenji Okumura, Joon Sub Lee, Abhay Dhand, Hiroshi Sogawa, Gregory Veillette, Devon John, Ryosuke Misawa, Roxana Bodin, David C Wolf, Thomas Diflo, Seigo Nishida, Department of Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY 10595, United States
Author contributions: Okumura K, Nishida S contributed to the study design, data analysis, data interpretation, and writing manuscript; Lee JS, Dhand A, Sogawa H, Veillette G, John D, Misawa R, Bodin R, Wolf DC, and Diflo T revised manuscript and critical revisions; and all authors approved the final version of the manuscript.
Institutional review board statement: All study methods were approved by our Institutional Review Board.
Informed consent statement: The informed consent statement was waived.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Data is available on request from the authors.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kenji Okumura, MD, Department of Surgery, Westchester Medical Center/New York Medical College, 100 Woods Road, Valhalla, NY 10595, United States. kenji.okumura@wmchealth.org
Received: January 16, 2022
Peer-review started: January 16, 2022
First decision: March 16, 2022
Revised: March 30, 2022
Accepted: July 31, 2022
Article in press: July 31, 2022
Published online: August 18, 2022
Core Tip

Core Tip: Liver transplantation (LT) among older patients is becoming more acceptable in the United States. The overall outcomes of LT for patients ≥ 65 years are comparable to younger recipients. While there is a higher risk of graft failure in older recipient population, age alone should not be a contraindication for LT. Careful selection of donors and recipients along with optimal management of risk factors during the postoperative period are necessary to maximize the transplant outcomes in this population.