Published online Jul 18, 2021. doi: 10.5500/wjt.v11.i7.263
Peer-review started: February 26, 2021
First decision: May 5, 2021
Revised: May 18, 2021
Accepted: June 18, 2021
Article in press: June 18, 2021
Published online: July 18, 2021
Core Tip: Over recent decades more attention has shifted to the psychosocial challenges associated with transplantation. The psychosocial difficulties accompanying transplantation are addressed in the context of both quality of life (QOL) and psychopathological research. Recently, more attention has been focused on the psychosocial burden of caregivers and psychosocial interventions in hematopoietic stem cell transplantation (HSCT) sufferers and close relatives. This review synthesizes the major issues on psychosocial aspects of HSCT including QOL research, psychosocial adaptation for HSCT, psychiatric comorbidities, and psychosocial interventions to improve QOL and reduce psychopathology in HSCT patients and close relatives.