Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jul 18, 2021; 11(7): 263-276
Published online Jul 18, 2021. doi: 10.5500/wjt.v11.i7.263
Psychosocial aspects of hematopoietic stem cell transplantation
Henrietta Janicsák, Gabor S Ungvari, Gábor Gazdag
Henrietta Janicsák, Gábor Gazdag, Department of Psychiatry and Psychiatric Rehabilitation, Jahn Ferenc South Pest Hospital, Budapest 1204, Hungary
Gabor S Ungvari, Division of Psychiatry, University of Notre Dame, Fremantle 6009, Australia
Gabor S Ungvari, Division of Psychiatry, School of Medicine, University of Western Australia, Perth 6009, Australia
Gábor Gazdag, Department of Psychiatry and Psychotherapy, Faculty of Medicine, Semmelweis University, Budapest 1083, Hungary
Author contributions: This review of the literature was Gazdag G’s idea; Janicsák H performed 80%, Gazdag G 20% of the literature search and the preparation of the first draft; Ungvari GS reviewed, commented on and corrected the manuscript; all authors approved the final version of the text.
Conflict-of-interest statement: Authors declare no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Gábor Gazdag, MD, PhD, Professor, Department of Psychiatry and Psychiatric Rehabilitation, Jahn Ferenc South Pest Hospital, Köves út 1, Budapest 1204, Hungary.
Received: February 26, 2021
Peer-review started: February 26, 2021
First decision: May 5, 2021
Revised: May 18, 2021
Accepted: June 18, 2021
Article in press: June 18, 2021
Published online: July 18, 2021
Core Tip

Core Tip: Over recent decades more attention has shifted to the psychosocial challenges associated with transplantation. The psychosocial difficulties accompanying transplantation are addressed in the context of both quality of life (QOL) and psychopathological research. Recently, more attention has been focused on the psychosocial burden of caregivers and psychosocial interventions in hematopoietic stem cell transplantation (HSCT) sufferers and close relatives. This review synthesizes the major issues on psychosocial aspects of HSCT including QOL research, psychosocial adaptation for HSCT, psychiatric comorbidities, and psychosocial interventions to improve QOL and reduce psychopathology in HSCT patients and close relatives.