Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 29, 2020; 10(6): 173-182
Published online Jun 29, 2020. doi: 10.5500/wjt.v10.i6.173
Published online Jun 29, 2020. doi: 10.5500/wjt.v10.i6.173
Living kidney donor assessment: Kidney length vs differential function
Jacob A Akoh, Katharina J Schumacher, Department of Surgery, Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth PL6 8DH, Devon, United Kingdom
Jacob A Akoh, South West Transplant Centre, Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth PL6 8DH, Devon, United Kingdom
Author contributions: Akoh JA and Schumacher KJ collected data; Akoh JA: designed study, analysed data, wrote paper, and critically appraised manuscript; Schumacher KJ collected data and wrote aspects of paper; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the University Hospitals Plymouth NHS Trust Institutional Review Board. Ethics approval and individual informed consent was not required.
Clinical trial registration statement: Not Applicable for this Manuscript.
Informed consent statement: Not Applicable for this Manuscript.
Conflict-of-interest statement: Both authors have no conflict of interests to declare.
Data sharing statement: There is no additional data available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jacob A Akoh, FRCS (Ed), FRCS (Gen Surg), MBBS, Associate Professor, Consultant General and Transplant Surgeon, Department of Surgery, Derriford Hospital, University Hospitals Plymouth NHS Trust, Derriford Road, Plymouth PL6 8DH, Devon, United Kingdom. jacob.akoh@nhs.net
Received: February 24, 2020
Peer-review started: February 24, 2020
First decision: April 18, 2020
Revised: May 19, 2020
Accepted: May 21, 2020
Article in press: May 21, 2020
Published online: June 29, 2020
Peer-review started: February 24, 2020
First decision: April 18, 2020
Revised: May 19, 2020
Accepted: May 21, 2020
Article in press: May 21, 2020
Published online: June 29, 2020
Core Tip
Core tip: Selection of which kidney to donate is of critical importance in living kidney donation. The decision-making process based on divided function and vascular anatomy was used to validate a retrospective “what if” analysis of prospectively reported kidney length measurements in a cohort of 285 potential donors. This study shows a significant risk for making wrong/harmful decision (removing the significantly better functioning kidney) if kidney length alone is used for decision making -25% if using 2 cm difference as cut off. Difference in length between kidney pairs alone is not sufficient to replace measurement of divided function.