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World J Transplant. Dec 28, 2020; 10(12): 372-380
Published online Dec 28, 2020. doi: 10.5500/wjt.v10.i12.372
Donor risk factors in pancreas transplantation
Luis Muñoz-Bellvís, Jaime López-Sánchez
Luis Muñoz-Bellvís, Jaime López-Sánchez, Department of General & Gastrointestinal Surgery, Hospital Universitario de Salamanca, Universidad de Salamanca, Salamanca 37007, Spain
Luis Muñoz-Bellvís, Jaime López-Sánchez, Salamanca Biomedical Research Institute (IBSAL), Universidad de Salamanca, Salamanca 37007, Spain
Author contributions: Muñoz-Bellvís L and López-Sánchez J performed and wrote the manuscript; All authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Luis Muñoz-Bellvís, MD, Doctor, Professor, Surgeon, Department of General & Gastrointestinal Surgery, Hospital Universitario de Salamanca, Universidad de Salamanca, Paseo de San Vicente 158, Salamanca 37007, Spain. luismb@usal.es
Received: June 20, 2020
Peer-review started: June 20, 2020
First decision: August 22, 2020
Revised: August 29, 2020
Accepted: October 9, 2020
Article in press: October 9, 2020
Published online: December 28, 2020
Processing time: 186 Days and 10.9 Hours
Core Tip

Core Tip: Pancreas transplantation remains the only treatment to restore euglycemia and hemoglobin A1c levels in diabetic patients. However, it presents high morbidity due to different postoperative complications and the effects of the immunosuppressive therapies. The pancreas transplantation complications occur more frequently in specific cases related to donor factors (high body mass index, older age, etc.). Several studies analyzed the donor and recipient risk factors. Knowing these risk factors allows us to establish specific selection criteria in pancreas transplantation and may improve its results.