Published online Nov 12, 2013. doi: 10.5499/wjr.v3.i3.25
Revised: September 23, 2013
Accepted: October 17, 2013
Published online: November 12, 2013
Core tip: identification of interleukin-17-producing cells (Th17) rise as important source of inflammatory cytokines, IL-17 in particular, with critical role during inflammatory diseases.In this paper, we reviewed the differentiation of these cells from naive lymphocytes, their role during inflammatory arthritis and therapeutic tools to control these cells.