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Opinion Review
Copyright: ©Author(s) 2026.
World J Psychiatry. Nov 19, 2026; 16(11): 116382
Published online Nov 19, 2026. doi: 10.5498/wjp.116382
Table 1 Comparative analysis of evidence-based psychological interventions for suicide attempters in emergency department settings
Intervention type
Core components
Target population
Duration/format
Key efficacy findings
Implementation considerations
SPICollaborative development of personalized crisis response plan; means restriction counseling; identification of warning signs and coping strategiesAll suicide attempters presenting to EDSingle session (20-45 minutes); often combined with follow-up contactsOdds ratio: 0.51 for suicide attempts vs usual care[4]; 43%-86% reduction in suicide-related ED visits in DBT programs[29]Can be delivered by trained nurses, social workers, or peers; requires standardized training and fidelity monitoring
Cognitive behavioral therapyCognitive restructuring; problem-solving skills; emotion regulation; behavioral activationHigh-risk patients with recurrent attempts or severe ideation6-12 sessions (individual or group); may be initiated in ED with community referralOdds ratio: 0.54 for repeat attempts[5]; 41% reduced risk via telehealth delivery[27]Requires specialized therapists; may involve task-shifting with supervision; telehealth adaptations show promise[20]
DBTMindfulness, distress tolerance, emotion regulation, interpersonal effectiveness skillsPatients with borderline personality traits, chronic suicidality, or emotion dysregulationComprehensive program (individual therapy, skills group, phone coaching, team consultation)Significant reductions in suicide attempts and self-harm[33]; digital DBT shows feasibility[15]Resource-intensive; requires specialized training; digital adaptations may increase accessibility[33]
Brief contact interventionsPostcards, letters, phone calls, text messages; caring contacts; systematic follow-upAll suicide attempters post-dischargeMultiple contacts over 6-12 months (e.g., 24-48 hours, 1 week, 1 month, 3 months, 6 months)24% reduced risk of relapse with early appointment scheduling[31]; active contact reduces repeat attempts within 6 months[30]Low-cost; can be automated or delivered by non-specialists; requires systematic tracking system[56,57]
Attempted Suicide Short Intervention ProgramTherapeutic alliance building; narrative reconstruction; safety planning; follow-up lettersFirst-time and repeat suicide attempters3-4 sessions plus follow-up letters over 24 monthsReduced suicide reattempts by 80% at 24-month follow-up[55]Brief format (3 sessions); manualized; requires therapist training[55]
Table 2 Implementation barriers and evidence-based solutions for emergency department suicide prevention programs
Barrier category
Specific barriers
Evidence-based solutions
Supporting evidence
Workforce and trainingLimited mental health specialists in ED; inadequate suicide risk assessment training; high staff turnoverTask-shifting with protocolized interventions; standardized training programs; telehealth consultation modelsNurse-led SPI implementation[20]; ED-SAFE training protocols[11]; SPCC telehealth model[40]
Workflow and resourcesTime constraints; competing clinical priorities; lack of dedicated space for interventionsIntegration into nursing discharge process; electronic health record prompts; dedicated “suicide prevention coordinator” roleSPI embedded in discharge workflow[29]; EHR clinical decision support[36]; follow-up coordinator models[45]
Assessment and documentationInconsistent risk assessment; lack of standardized tools; poor documentationMandatory use of validated tools (Columbia-Suicide Severity Rating Scale); structured documentation templates; automated risk scoringColumbia-Suicide Severity Rating Scale validation in ED settings[44]; standardized assessment protocols[11]
Care coordinationFragmented post-ED care; poor communication with outpatient providers; lost to follow-upWarm hand-offs; shared EHR alerts; fixed appointment timelines (≤ 7 days); centralized follow-up systemsIntegrated care pathways[49]; formal community partnerships[12]; systematic contact protocols[31]
Cultural and systemicStigma; organizational resistance; lack of leadership support; funding constraintsImplementation science frameworks (RE-AIM, CFIR); leadership engagement; quality improvement initiativesZero suicide framework implementation[36]; organizational readiness assessment[13]
Technology and accessDigital divide; privacy concerns; interoperability issuesHybrid models (in-person + digital); app-based safety planning; telehealth follow-upDigital DBT interventions[15]; SPI apps[23]; telehealth service models[40]
Table 3 Cost-effectiveness analysis of emergency department-based suicide prevention interventions
Intervention
Incremental cost per patient
Effectiveness (suicide attempts averted)
Cost per life-year saved
Population impact
Key studies
Universal screening + telephone intervention$500 more than screening alone10% reduction in attempts/deaths at 12 months$4300 per life-year savedPotential savings of $840M annually if 25% of attempts avertedED-SAFE cost analysis[11]
Postcard/caring lettersCost-saving compared to usual careSignificant reduction in repeat attemptsDominant strategy (improves outcomes, reduces costs)Low-cost, scalable population-level interventionModeling studies[60,61]
Safety planning intervention$1063 per month per patient (telehealth model)Reduced suicidal behavior and healthcare utilizationTo be determined in ongoing trialsPotential for system-wide cost offsets through reduced acute careSPCC trial protocol[40]
Cognitive behavioral therapy$18800 per life-year saved41%-54% reduction in repeat attemptsCost-effective at WTP ≥ $50000 per life-yearTargeted approach for high-risk populationsEconomic evaluation[26,27]
Brief contact interventionsMinimal incremental cost24% reduced relapse risk with early appointmentHighly cost-effectiveCan be integrated into existing follow-up systemsObservational studies[31]


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