Effect of comprehensive intervention model based on drug-psychology-society-skills on medication compliance and cognitive ability of chronic schizophrenia patients

Table 1 Comparison of mini mental assessment scale and Montreal cognitive assessment scale scores between the two groups, mean ± SD

Group	Number of cases	MMSE score		MoCA score
		Before intervention	After intervention	Before intervention	After intervention
Research group (n = 48)	48	22.25 ± 2.47	27.15 ± 2.58	23.31 ± 2.14	26.58 ± 3.21a
Control group (n = 48)	48	22.33 ± 2.71	26.24 ± 2.36	23.44 ± 2.09	24.68 ± 3.02a
t value		0.151	1.803	0.301	2.987
P value		0.880	0.075	0.764	0.004

^aP < 0.05.

MMSE: Mini mental assessment scale; MoCA: Montreal cognitive assessment scale.

Table 2 Comparison of positive and negative syndrome scale score between two groups, mean ± SD

Group	Number of cases	Positive symptom score		Negative symptom score
		Before intervention	After intervention	Before intervention	After intervention
Research group (n = 48)	48	15.38 ± 2.45	12.01 ± 2.58a	35.22 ± 2.65	32.51 ± 2.11a
Control group (n = 48)	48	15.66 ± 1.94	14.54 ± 2.33a	35.53 ± 2.01	33.74 ± 2.55a
t value		0.621	5.042	0.646	2.575
P value		0.536	0.000	0.520	0.012

^aP < 0.05.

Table 3 Comparison of insight and treatment attitudes questionnaire scores before and after treatment, mean ± SD

Group	ITAQ score
	Before intervention	After intervention
Research group (n = 48)	5.23 ± 3.45	13.56 ± 6.35a
Control group (n = 48)	5.79 ± 3.04	7.97 ± 3.02a
t value	0.843	5.508
P value	0.402	0.000

^aP < 0.05.

ITAQ: Insight and treatment attitudes questionnaire.

Table 4 Comparison of MATRICS consensus cognitive battery scores between the two groups, mean ± SD

Group	Number of cases	Before intervention	After intervention
Research group (n = 48)	48	34.45 ± 5.22	43.51 ± 6.01a
Control group (n = 48)	48	34.24 ± 5.62	38.44 ± 6.23a
t value		0.190	4.058
P value		0.850	0.000

^aP < 0.05.

Table 5 Comparison of personal and social performance scale scores between the two groups, mean ± SD

Group	PSP		t value	P value
	Before intervention	After intervention
Research group (n = 48)	46.79 ± 7.31	78.38 ± 6.63	22.177	0.000
Control group (n = 48)	45.51 ± 7.26	74.52 ± 7.01	19.916	0.000
t value	0.861	2.772
P value	0.382	0.007

PSP: Personal and social performance scale.

Table 6 Comparison of the incidence of adverse reactions during treatment, n (%)

Group	Extrapyramidal reaction	Put on weight	Elevated blood sugar	Hyperlipidemia	Incidence rate
Research group (n = 48)	1 (2.08)	0 (0.00)	0 (0.00)	2 (4.17)	3 (6.25)
Control group (n = 48)	2 (4.17)	0 (0.00)	0 (0.00)	2 (4.17)	4 (8.33)
χ2	0.205
P value	0.36