Observational Study
Copyright ©The Author(s) 2020.
World J Psychiatr. Sep 19, 2020; 10(9): 212-222
Published online Sep 19, 2020. doi: 10.5498/wjp.v10.i9.212
Table 1 Cases of delirium and no delirium (according to confusion assessment method) with the scores (mean ± SD) of the Montreal cognitive assessment, acute physiology and chronic health evaluation II and growth hormone, insulin-like growth factor I levels at each assessment point
AssessmentCAM (n)MoCAAPACHE IIIGF-I (ng/mL)GH (pg/mL)
1No delirium (173)mean ± SD11.38 ± 7.908.59 ± 3.6861.32 ± 22.95503.95 ± 743.05
Valid, n1681736868
Delirium (24)mean ± SD3.78 ± 2.769.00 ± 3.8645.88 ± 14.66693.89 ± 462.15
Valid, n232488
2No delirium (141)mean ± SD10.42 ± 8.238.69 ± 3.6953.93 ± 18.57434.22 ± 561.88
Valid, n1341404949
Delirium (11)mean ± SD3.67 ± 3.4311.00 ± 5.2041.78 ± 13.98652.14 ± 346.98
Valid, n91155
3No delirium (90)mean ± SD9.27 ± 7.588.77 ± 3.6760.66 ± 18.88487.98 ± 648.70
Valid, n84883030
Delirium (13)mean ± SD3.90 ± 2.5110.38 ± 3.6958.29 ± 14.60487.25 ± 507.84
Valid, n101355
4No delirium (58)mean ± SD10.63 ± 7.448.79 ± 3.5561.97 ± 22.70622.00 ± 790.09
Valid, n56581818
Delirium (8)mean ± SD6.00 ± 1.839.00 ± 2.6741.43 ± 8.13577.94 ± 200.90
Valid, n7822
5No delirium (46)mean ± SD8.70 ± 7.208.80 ± 3.2853.70 ± 14.37288.27 ± 245.51
Valid, n43461111
Delirium (6)mean ± SD2.33 ± 1.039.50 ± 3.3342.62 ± 2.42924.34 ± 677.88
Valid, n6644
Table 2 Generalized estimating equations model and parameter estimates of the significant variables on delirium status
Parameter estimates
ParameterBSE95%CI
Hypothesis test
LowerUpperWald χ2uSig.
GH (pg/ml)-0.001110.0002-0.00106.2110.013
IGF-1 (ng/ml)0.020.00740.0050.0347.19610.007
MoCA0.2050.05860.090.3212.2311< 0.001