Copyright ©The Author(s) 2024.
World J Psychiatry. Feb 19, 2024; 14(2): 210-214
Published online Feb 19, 2024. doi: 10.5498/wjp.v14.i2.210
Table 1 British Association of Psychopharmacology evidence-based consensus guidelines for the management of catatonia: Summary of key recommendations
Recommendation category
General approach and first-line treatmentEmphasised use of GABA-ergic pharmacotherapies as first-line treatment; followed by recommendation for management of non-response, and considering underlying conditions, and potential complications
Other therapiesUse of ECT, evolving treatment modalities like N-methyl-D-aspartate receptor antagonists, dopamine precursors, agonists and reuptake inhibitors, dopamine receptor antagonists and partial agonists, anticonvulsants, anticholinergic agents, miscellaneous treatments; alternatives to ECT include repetitive transcranial magnetic stimulation and transcranial direct-current stimulation
Subtypes of catatonia and related conditionsSpecific recommendations for periodic catatonia, malignant catatonia, neuroleptic malignant syndrome, and medication-induced catatonia
Special groups and situationsConsiderations for children and adolescents, older adults, the perinatal period (including the safety of lorazepam and use of ECT), individuals with autism spectrum disorder, and those with certain medical conditions
Research prioritiesEmphasises the need for more randomised controlled trials and prospective cohort studies to strengthen evidence base for management of catatonia