Published online Jun 9, 2014. doi: 10.5497/wjp.v3.i2.18
Revised: June 4, 2014
Accepted: June 5, 2014
Published online: June 9, 2014
Core tip: Vascular tone is regulated in part by cytosolic calcium oscillations. Arsenic can induce an increase in vascular tone and resistance. We suggest a model explaining the participation of the sodium pump and Na+-K+-2Cl- co-transporter in low dose arsenic exposure effects on vasomotion and vascular dysfunction.