Published online Nov 27, 2014. doi: 10.5496/wjmg.v4.i4.105
Revised: July 11, 2014
Accepted: August 27, 2014
Published online: November 27, 2014
Core tip: Human leukocyte antigens (HLA) identical stem cell transplant is the key in achieving an acceptable engraftment and survival in stem cell therapy. However, the availability of the HLA matched donors even among family members is extremely limited, so preimplantation HLA typing provides an attractive practical tool of stem cell therapy for children requiring HLA matched stem cell transplantation.