Basic Study
Copyright ©The Author(s) 2023.
World J Clin Infect Dis. Feb 28, 2023; 13(1): 1-10
Published online Feb 28, 2023. doi: 10.5495/wjcid.v13.i1.1
Table 1 Selected templates for comparative modeling
Antigen
Template (PDB)
Organism
Identity (%)
X-ray resolution (Å)
GMQE
ML20383UOIM. tuberculosis90.511.900.96
ML00503FAVM. tuberculosis40.002.150.74
ML02863EKLM. tuberculosis87.461.510.96
85B Aga1F0NM. tuberculosis85.211.800.81
Table 2 Validation of three-dimensional models of the Mycobacterium leprae antigens
Antigen
Identification
Functional structure
MolProbity Score
Ramachandran plota (%)
Outliers (%)
ML2038BacterioferritinHomopolymer1.3198.480.08
ML0050ESAT-6-like protein esxBMonomer0.7798.610.00
ML0286Fructose-bisphosphate aldolaseHomotetramer1.3296.470.59
85B Ag85B antigenMonomer1.8593.950.00