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World J Clin Infect Dis. Aug 25, 2014; 4(3): 9-15
Published online Aug 25, 2014. doi: 10.5495/wjcid.v4.i3.9
Prosthetic joint infections-a clinico-microbiological perspective: Review article
Pravin K Nair, Vivek G Bhat, Michelle S Vaz
Pravin K Nair, Michelle S Vaz, Department of Microbiology, Holy Spirit Hospital, Andheri (E), Mumbai 400093, India
Vivek G Bhat, Department of Microbiology, ACTREC-Tata Memorial Center, Navi Mumbai 410210, India
Author contributions: All the authors contributed equally to the work in literature survey and writing of the paper.
Correspondence to: Vivek G Bhat, MD, Associate Professor-Microbiology, Advanced Centre for Treatment, Research and Education in Cancer, Department of Microbiology, ACTREC-Tata Memorial Centre, Navi Mumbai 410210, India.
Telephone: +91-22-27405093 Fax: +91-22-27405061
Received: June 24, 2014
Revised: July 21, 2014
Accepted: August 20, 2014
Published online: August 25, 2014
Core Tip

Core tip: Prosthetic joint infections (PJIs), although uncommon, may be associated with significant complications and morbidity. Staphylococci are among the most commonly involved organisms. Diagnosis may be challenging in spite of the availability of various laboratory and radiological tests. Treatment too, is often difficult because most infections are caused by biofilm producing organisms. A combination of prudent surgical intervention and specific antibiotic treatment is the key to a successful management. Thus, a multidisciplinary approach is the best option in dealing with PJI, and should involve a team of orthopedic specialists, clinicians, pathologists, radiologists and microbiologists to ensure best outcomes.