Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Exp Med. May 20, 2015; 5(2): 103-109
Published online May 20, 2015. doi: 10.5493/wjem.v5.i2.103
Mood disorders: A potential link between ghrelin and leptin on human body?
Stalo Zarouna, Greta Wozniak, Anastasia Ioannis Papachristou
Stalo Zarouna, Psychology Department, University of Cyprus, Nicosia 1678, Cyprus
Greta Wozniak, Basic Medical Science, Medical Pharmacology, Medical School, University of Cyprus, Nicosia 1678, Cyprus
Anastasia Ioannis Papachristou, School of Medicine, University of Crete, Voutes Campus, Heraklion, GR-71003 Crete, Greece
Author contributions: All authors contributed to this paper.
Conflict-of-interest: None conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Greta Wozniak, MD, PhD, Assistant Professor of Basic Medical Science, Medical Pharmacology, Medical School, University of Cyprus, Kallipoleos 75, Nicosia 1678, Cyprus.
Telephone: +357-22-895221 Fax: +357-22-895221
Received: September 26, 2014
Peer-review started: September 28, 2014
First decision: December 17, 2014
Revised: January 9, 2015
Accepted: January 30, 2015
Article in press: February 2, 2015
Published online: May 20, 2015
Core Tip

Core tip: Mood disorders are affecting a major amount of the world population. Considering the multiple factors that are contributing in the development of mood disorders, this review emphasizes on the role of leptin and ghrelin hormones. These two hormones have a key role in energy balance but they also have an effect on other physiological functions too, therefore we emphasize on the recent findings which raise a potential link between the hormones and the disorders of mood.