Copyright
©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Prognostic role of tumor budding in breast cancer
Ioannis A Voutsadakis, Algoma District Cancer Program, Sault Area Hospital, Sault Ste. Marie, Ontario, Canada; and Section of Internal Medicine, Division of Clinical Sciences, Northern Ontario School of Medicine, Sudbury, P3E 2C6, Canada
Author contributions: Voutsadakis IA is the sole contributor in the conception and writing of this article.
Conflict-of-interest statement: The author declares no conflicts of interest regarding this paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ioannis A Voutsadakis, MD, PhD, Doctor, Algoma District Cancer Program, Sault Area Hospital, 750 Great Northern Road, Sault Ste Marie, ON P3E 2C6, Canada. ivoutsadakis@yahoo.com
Telephone: +1-705-7593434 Fax: +1-705-7593434
Received: July 5, 2018
Peer-review started: July 5, 2018
First decision: August 2, 2018
Revised: August 4, 2018
Accepted: August 12, 2018
Article in press: August 13, 2018
Published online: September 7, 2018
Peer-review started: July 5, 2018
First decision: August 2, 2018
Revised: August 4, 2018
Accepted: August 12, 2018
Article in press: August 13, 2018
Published online: September 7, 2018
Core Tip
Core tip: Tumor budding, defined as scattered cells or small islands of tumor cells in the vicinity but not connected to the main tumor mass, is a common occurrence in different cancers. In breast cancer, it may portend an adverse prognosis.