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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Aug 7, 2020; 9(3): 43-53
Published online Aug 7, 2020. doi: 10.5492/wjccm.v9.i3.43
Published online Aug 7, 2020. doi: 10.5492/wjccm.v9.i3.43
Ventilator-associated pneumonia in patients with cancer: Impact of multidrug resistant bacteria
Patricia Cornejo-Juárez, Ivan González-Oros, Paola Mota-Castañeda, Diana Vilar-Compte, Patricia Volkow-Fernández, Infectious Diseases Department, Instituto Nacional de Cancerología (INCan), Mexico City 14080, Mexico
Author contributions: Cornejo-Juárez P designed, made the analysis and wrote the paper; González-Oros I and Mota-Catañeda P performed the research; Vilar-Compte D and Volkow-Fernández P supervised the report and made intellectual contributions.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Instituto Nacional de Cancerología (2019/0096).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data and the confidentiality of the patients was preserved.
Conflict-of-interest statement: All the authors declare do not have conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Patricia Cornejo-Juárez, MD, MSc, Assistant Professor, Chief Doctor, Infectious Diseases Department, Instituto Nacional de Cancerología (INCan), Av. San Fernando No. 22, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, Mexico. patcornejo@yahoo.com
Received: December 16, 2019
Peer-review started: December 16, 2019
First decision: April 2, 2020
Revised: May 22, 2020
Accepted: June 14, 2020
Article in press: June 14, 2020
Published online: August 7, 2020
Peer-review started: December 16, 2019
First decision: April 2, 2020
Revised: May 22, 2020
Accepted: June 14, 2020
Article in press: June 14, 2020
Published online: August 7, 2020
Core Tip
Core tip: This is a retrospective study to evaluate the risk factors for ventilator-associated pneumoniae (VAP) in patients with cancer who are admitted at an intensive care unit and require mechanical ventilation for > 48 h. We emphasized in microbiology etiology, particularly multidrug resistant bacteria (MDRB). We included 263 patients during 2 year-period; 32 developed VAP, with a rate of 11.5 episodes/1000 ventilation-days. Gram-negative bacteria were isolated in 95% of cases, being the rate of MDRB 24.1%. Sixty-day mortality was 53% in VAP and 43% without VAP. There was not higher mortality in patients with MDRB.