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World J Crit Care Med. Nov 4, 2013; 2(4): 48-55
Published online Nov 4, 2013. doi: 10.5492/wjccm.v2.i4.48
Published online Nov 4, 2013. doi: 10.5492/wjccm.v2.i4.48
Molecular targeting therapy using bevacizumab for peritoneal metastasis from gastric cancer
Keishiro Aoyagi, Kikuo Kouhuji, Motoshi Miyagi, Junya Kizaki, Taro Isobe, Kousuke Hashimoto, Kazuo Shirouzu, Department of Surgery, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan
Author contributions: Aoyagi K was responsible for writing and revising the full text original article in response to an invitation from an editorial office member of the WJCCM ; Kouhuji K instructed the research and clinical work; Miyagi M established the high potential peritoneal dissemination cell line MKN-45P; Kizaki J cultured the two cell lines and measured the concentration of various cytokines; Isobe T performed the in vivo study on the peritoneal dissemination model using nude mice; Hasimoto K performed the pathological study on the intra-abdominal tumor of nude mice; and Professor Shirouzu K, Chair of the Department of Surgery, provided useful critique and advice for our research.
Correspondence to: Keishiro Aoyagi, Assistant Professor, Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan. keishiro@med.kurume-u.ac.jp
Telephone: +81-942-353311 Fax: +81-942-340709
Received: May 2, 2013
Revised: June 5, 2013
Accepted: July 4, 2013
Published online: November 4, 2013
Revised: June 5, 2013
Accepted: July 4, 2013
Published online: November 4, 2013
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