Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Crit Care Med. Sep 9, 2026; 15(3): 115627
Published online Sep 9, 2026. doi: 10.5492/wjccm.115627
Published online Sep 9, 2026. doi: 10.5492/wjccm.115627
Prognostic utility of on-admission pulse pressure in hospitalized patients with traumatic brain injury
Khalid Ahmed, Ayman El-Menyar, Mohammad Asim, Hisham Al Jogol, Ibrahim Taha, Ahad Kanbar, Basil Younis, Sandro Rizoli, Hassan Al-Thani, Department of Surgery, Trauma Surgery, Hamad Medical Corporation, Doha 3050, Qatar
Ayman El-Menyar, Department of Clinical Medicine, Weill Cornell Medicine, Doha 24144, Qatar
Co-first authors: Khalid Ahmed and Ayman El-Menyar.
Author contributions: Ahmed K and El-Menyar A contributed to the conceptualization of the study and contributed equally to this manuscript as co-first authors; El-Menyar A and Asim M contributed to study methodology; Al Jogol H, Taha I, Kanbar A, and Younis B contributed to data curation; Ahmed K participated in the original draft preparation; Rizoli S and Al-Thani H reviewed and edited the manuscript. All authors have read and approved the final version of the manuscript.
Institutional review board statement: This retrospective study was approved by the Medical Research Center Institutional Review Board (approval no: MRC-01-21-990).
Informed consent statement: Patients were not required to provide informed consent for this study because the analysis used anonymized clinical data obtained after each patient had provided written informed consent for treatment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All relevant data are presented in the manuscript, figures, and tables.
Corresponding author: Ayman El-Menyar, MD, Department of Surgery, Trauma Surgery, Hamad Medical Corporation, Al-Rayyan Street, Doha 3050, Qatar. aymanco65@yahoo.com
Received: October 22, 2025
Revised: November 19, 2025
Accepted: January 27, 2026
Published online: September 9, 2026
Processing time: 309 Days and 19.1 Hours
Revised: November 19, 2025
Accepted: January 27, 2026
Published online: September 9, 2026
Processing time: 309 Days and 19.1 Hours
Core Tip
Core Tip: Traumatic brain injury is a major contributor to long-term disability. Hemodynamic parameters, including mean arterial pressure and pulse pressure (PP), play a critical role in maintaining cerebral perfusion, regulating intracranial pressure, and mitigating secondary brain injury. Admission PP reflects both hemodynamic stability and injury severity in patients with brain injury. Low PP (≤ 30 mmHg) independently predicts higher mortality, whereas moderate PP is associated with optimal outcomes, suggesting that this range represents a potential hemodynamic target. PP is a simple bedside adjunct marker that aids early risk stratification and guides timely intervention in patients with traumatic brain injury.