Meta-Analysis
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Jul 9, 2022; 11(4): 298-310
Published online Jul 9, 2022. doi: 10.5492/wjccm.v11.i4.298
Association between early viral lower respiratory tract infections and subsequent asthma development
Sebastien Kenmoe, Etienne Atenguena Okobalemba, Guy Roussel Takuissu, Jean Thierry Ebogo-Belobo, Martin Gael Oyono, Jeannette Nina Magoudjou-Pekam, Ginette Irma Kame-Ngasse, Jean Bosco Taya-Fokou, Chris Andre Mbongue Mikangue, Raoul Kenfack-Momo, Donatien Serge Mbaga, Arnol Bowo-Ngandji, Cyprien Kengne-Ndé, Seraphine Nkie Esemu, Richard Njouom, Lucy Ndip
Sebastien Kenmoe, Seraphine Nkie Esemu, Lucy Ndip, Department of Microbiology and Parasitology, University of Buea, Buea 00237, Cameroon
Sebastien Kenmoe, Richard Njouom, Department of Virology, Centre Pasteur of Cameroon, Yaounde 00237, Cameroon
Etienne Atenguena Okobalemba, Faculty of Medicine and Biomedical Science, The University of Yaounde I, Yaounde 00237, Cameroon
Guy Roussel Takuissu, Centre of Research in Food, Food Security and Nutrition, Institute of Medical Research and Medicinal Plants Studies, Yaounde 00237, Cameroon
Jean Thierry Ebogo-Belobo, Ginette Irma Kame-Ngasse, Medical Research Centre, Institute of Medical Research and Medicinal Plants Studies, Yaounde 00237, Cameroon
Martin Gael Oyono, Laboratory of Parasitology and Ecology, The University of Yaounde I, Yaounde 00237, Cameroon
Jeannette Nina Magoudjou-Pekam, Raoul Kenfack-Momo, Department of Biochemistry, The University of Yaounde I, Yaounde 00237, Cameroon
Jean Bosco Taya-Fokou, Chris Andre Mbongue Mikangue, Donatien Serge Mbaga, Arnol Bowo-Ngandji, Department of Microbiology, The University of Yaounde I, Yaounde 00237, Cameroon
Cyprien Kengne-Ndé, Epidemiological Surveillance, Evaluation and Research Unit, National Aids Control Committee, Douala 00237, Cameroon
Author contributions: Kenmoe S, Ndip L, and Njouom R were responsible for conception and design of the study as well as project administration; Kenmoe S, Atenguena Okobalemba E, Takuissu GR, Ebogo-Belobo JT, Oyono MG, Magoudjou-Pekam JN, Kame-Ngasse GI, Taya-Fokou JB, Mbongue Mikangue CA, Kenfack-Momo R, Fall A, Mbaga DS, Bowo-Ngandji A, Kengne-Nde C, and Esemu SN were responsible for the data curation and interpretation of results; Kengne-Nde C and Kenmoe S were responsible for statistical analysis; Kenmoe S, Ndip L, and Njouom R were responsible for the project supervision; Kenmoe S wrote the original draft; All authors critically reviewed the first draft and approved the final version of the paper for submission and have read and approved the final manuscript.
Supported by the European Union (EDCTP2 Programme), No. TMA2019PF-2705.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sebastien Kenmoe, PhD, Assistant Lecturer, Department of Microbiology and Parasitology, University of Buea, Molyko to Buea Town Rd, Buea 00237, Cameroon. sebastien.kenmoe@ubuea.cm
Received: November 30, 2021
Peer-review started: November 30, 2021
First decision: April 19, 2022
Revised: April 25, 2022
Accepted: June 16, 2022
Article in press: June 16, 2022
Published online: July 9, 2022
Core Tip

Core Tip: The results of this meta-analysis confirmed that viral lower respiratory tract infections (LRTIs) in children < 2 years increase the risk of developing asthma later until the age of 20 years. This indicates that pediatricians and parents should be vigilant with anticipating asthma preventive measures in children with viral LRTIs in childhood.