Molecular biology techniques for the surgeon

Figure 1 Hybridization of the target to the probe. Probes are fixed to the matrix and labeled targets are allowed to hybridize with the probes (source: public domain).

Figure 2 SILAC-heavy and light arginine is placed in growth medium for cultured cells. Incorporation of the light and heavy arginine results in a mass shift of corresponding peptides. Mass spectroscopy is then utilized to detect the ratios of the peak intensities. The ratio reflects the relative protein abundance in the two samples. Arg: Arginine. (Source: public domain).