Kowdley G, Srikantan S, Abdelmohsen K, Gorospe M, Khan J. Molecular biology techniques for the surgeon. World J Surg Proced 2012; 2(2): 5-15 [DOI: 10.5412/wjsp.v2.i2.5]
Corresponding Author of This Article
Gopal Kowdley, MD, PhD, General Surgeon, Associate Program Director, Department of Surgery, St Agnes Hospital, 900 S. Caton Ave, Baltimore, MD 21229, United States. gkowdley@gmail.com
Article-Type of This Article
Topic Highlight
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Gopal Kowdley, Javeed Khan, Department of Surgery, St Agnes Hospital, Baltimore, MD 21229, United States
Gopal Kowdley, Subramanya Srikantan, Kotb Abdelmohsen, Myriam Gorospe, Laboratory of Molecular Biology and Immunology, National Institute on Aging, NIH, Baltimore, MD 21224, United States
Author contributions: All authors contributed equally to this review.
Supported by The National Institute on Aging-Intramural Research Program, National Institutes of Health
Correspondence to: Gopal Kowdley, MD, PhD, General Surgeon, Associate Program Director, Department of Surgery, St Agnes Hospital, 900 S. Caton Ave, Baltimore, MD 21229, United States. gkowdley@gmail.com
Telephone: +1-443-9283932 Fax:+1-410-9514007
Received: October 10, 2011 Revised: March 20, 2012 Accepted: March 27, 2012 Published online: April 28, 2012
Abstract
New technologies are constantly being introduced into the medical and surgical fields. These technologies come in the form of newer medicines, imaging methods and prognostic tools, among others, and allow clinicians to make more rational and informed decisions on the care of their patients. Many of these technologies utilize advanced techniques which are at the forefront of many research fields and represent a transition of bench advances into the clinical realm. This review will highlight four technologies that are at the forefront in the treatment of oncology patients treated by surgeons on a daily basis. Circulating tumor cells, microarray analysis, proteomic studies and rapid sequencing technologies will be highlighted. These technologies will be reviewed and their potential use in the care of surgical patients will be discussed.
