Copyright ©The Author(s) 2016.
World J Immunol. Mar 27, 2016; 6(1): 39-59
Published online Mar 27, 2016. doi: 10.5411/wji.v6.i1.39
Figure 2
Figure 2 Vitamin D and retinoic acid biosynthesis and activity. A: Vitamin D biosynthetic pathways are indicated, showing critical enzymes in particular tissues. Binding of VDR to DNA with RXR is indicated in a T cell; B: Retinoic acid biosynthetic pathways are indicated. Binding of RAR to DNA with RXR is indicated in an immune cell. RXR: Retinoid X receptor; VDR: Vitamin D receptor; RAR: Retinoic acid receptor; CRBP: Cellular retinol-binding proteins; RDH: Retinol dehydrogenases; VDRE: Vitamin D response element; RARE: Retinoic acid response element; CRABP: Cellular retinoic acid binding proteins.