Historical evolution, overview, and therapeutic manipulation of co-stimulatory molecules
Henry Velazquez-Soto, Fernanda Real, Maria C Jiménez-Martínez, Department of Immunology and Research Unit, Institute of Ophthalmology “Conde de Valenciana”, Mexico City 06800, Mexico
Maria C Jiménez-Martínez, Department of Biochemistry, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico
Author contributions: Velazquez-Soto H drafted the paper and designed the outline; Real F prepared the figures and tables, and reviewed the paper; Jiménez-Martínez MC reviewed the paper, figures and tables, coordinated the paper’s preparation, and approved the final version.
Supported by Institute of Ophthalmology “Fundación Conde de Valenciana”; Velazquez-Soto H received fellowship 294674 from CONACYT during his doctoral studies in Programa de Doctorado en Ciencias Médicas, Odontológicas y de la Salud (Farmacología Clínica), Universidad Nacional Autónoma de México (UNAM); Real F with CVU 917729, recieved fellowship from CONACYT during his master studies in Programa de Maestría en Ciencias Médicas, Odontológicas y de la Salud (Farmacología Clínica), Universidad Nacional Autónoma de México (UNAM).
Conflict-of-interest statement: The authors declare that they have no conflicting interests.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maria C Jiménez-Martínez, MD, PhD, Chief Doctor, Department of Immunology and Research Unit, Institute of Ophthalmology “Conde de Valenciana”, Chimalpopoca 14, Col. Obrera, Del. Cuauhtemoc, Mexico City 06800, Mexico. firstname.lastname@example.org
Received: April 28, 2021
Peer-review started: April 28, 2021
First decision: July 8, 2021
Revised: August 5, 2021
Accepted: December 22, 2021
Article in press: December 22, 2021
Published online: January 24, 2022