Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Urol. Nov 24, 2015; 4(3): 108-114
Published online Nov 24, 2015. doi: 10.5410/wjcu.v4.i3.108
Is continuous bladder irrigation after prostate surgery still needed?
Chukwudi Ogonnaya Okorie
Chukwudi Ogonnaya Okorie, Department of Surgery, Federal Teaching Hospital, Abakaliki 102, Ebonyi State, Nigeria
Chukwudi Ogonnaya Okorie, Department of Surgery, Ebonyi State University, Abakaliki 102, Ebonyi State, Nigeria
Author contributions: Okorie CO collected the data and wrote the paper.
Conflict-of-interest statement: The author declares no conflict of interest for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Chukwudi Ogonnaya Okorie, MD, PhD, Department of Surgery, Federal Teaching Hospital, Abakaliki 102, Ebonyi State, Nigeria.
Telephone: +234-70-33647464
Received: May 20, 2015
Peer-review started: May 20, 2015
First decision: August 19, 2015
Revised: October 17, 2015
Accepted: November 13, 2015
Article in press: November 17, 2015
Published online: November 24, 2015


Continuous bladder irrigation (CBI) is commonly prescribed after certain prostate surgeries to help prevent the clot formation and retention that are frequently associated with these sometimes hemorrhagic surgeries. However, it remains unknown how effective CBI is in preventing clot formation/catheter blockage because these complications still frequently occur in the presence of CBI. On the other hand, the outcome of prostate surgeries has significantly improved over the years, and these surgeries have generally become much safer and, in many hands, less hemorrhagic. Newer surgical options such as holmium laser enucleation of the prostate with associated improved hemorrhagic control have also been introduced, further creating the opportunity to eliminate CBI. Furthermore, there is a lack of review articles on CBI. Hence, this article will review the evolution and contemporary role of CBI in prostate surgeries. To eliminate CBI after prostate surgeries, it is important to achieve good hemostasis during the surgeries. Having in place a policy of non-irrigation after prostate surgeries is also important if less CBI is to be the norm. A non-irrigation policy will hopefully help reduce those cases of CBI prescribed out of long-standing surgical tradition while allowing for cases prescribed out of compelling necessity. The author’s policy of a consistent non-CBI during prostate surgeries over the last 9 years will be highlighted.

Key Words: Continuous bladder irrigation, Bladder irrigation, Bladder washout, Benign prostatic hyperplasia, Prostatectomy, Transurethral resection of the prostate, Holmium enucleation of the prostate

Core tip: Continuous bladder irrigation (CBI) has been part and parcel of some prostate surgeries and might have been more relevant during the era of unpredictable hemostatic control. Hemostatic control during prostate surgeries has significantly improved, and new technologies with associated improved hemostasis have been introduced. Hence, CBI can be safely avoided in most prostate surgeries, especially when good hemostasis has been achieved and a policy to pursue the non- CBI pathway is in place.


Continuous bladder irrigation (CBI) can be defined as an uninterrupted and simultaneous infusion and drainage of the bladder with fluid. CBI is commonly used after some surgical procedures on the prostate [transurethral resection of the prostate (TURP), open prostatectomy] and also on the bladder [transurethral resection of bladder tumor (TURBT)]. Post-operative CBI is so commonly used that it remains a standard recommendation in urologic textbooks and journal articles[1-9] and is also a component of practical nursing training[10-14]. Over the years, CBI was developed and used as a valuable method of managing hemorrhage and clot formation after prostate surgeries[15-24]. However, it remains unknown how effective CBI is in preventing clot formation/catheter blockage because these complications still frequently occur in the presence of CBI[25]. Furthermore, there are no evidence-based guidelines for bladder irrigation strategies. On the other hand, the outcome of prostate surgeries (TURP and open prostatectomy) has significantly improved over these years, and these surgeries have generally become much safer and, in many hands, less hemorrhagic[6,25-37]. As such, it becomes pertinent to review the contemporary role of CBI in prostate surgeries, especially in TURP and open prostatectomy where CBI is most commonly used, but also in holmium enucleation of the prostate (HoLEP), which is currently considered the endourologic equivalent of open prostatectomy. Of note, there is a lack of review articles on CBI, and it is hoped that this article will help fill that gap.

Historical background of bladder irrigation

The evolution of bladder drainage and subsequently that of bladder irrigation is closely related to the problem of hemorrhage and clot formation associated with surgeries involving the prostate and also the bladder. The concept of bladder drainage and bladder irrigation has evolved over many years and has especially been part and parcel of surgery for benign prostatic hyperplasia (BPH). Byrne[16] found that a significant percentage of deaths that occur secondary to hemorrhage after prostatectomy can be attributed to inadequate catheter drainage of the bladder. According to Tinckler[19], apart from general patient management, patient care following prostatectomy is mainly concerned with ensuring uninterrupted drainage of urine and blood from the lower urinary tract until normal hemostasis is attained, avoiding accumulation of blood and clot retention. The frequent and frustrating experience of preventing catheter blockage is of much burden to both the patient and the medical staff, but most especially to the nurses who are more directly involved in monitoring the drainage function of these catheters. Lowthian P expressed this frustration in a graphic letter to the Editor of BJU[38]. Hence, ensuring adequate catheter drainage has always been an integral component of surgical procedures on the prostate and bladder.

Postoperative drainage of the bladder has been effected through the perineum, bladder and urethra. Fuller[39] inserted a tube through the perineum into the bladder and irrigated the bladder with hot water to aid hemostasis and wash out blood clots. Cabot[40] described a double glass tube that was inserted suprapubically and used to irrigate and drain the bladder using water. Other suprapubic drains of interest include those of Herman et al[41]. According to McEachern[42], the introduction of the Harris prostatectomy and development of transurethral resection of the prostate helped bring to the frontline the enormity associated with the care of indwelling urethral catheters, especially the necessity of frequent bladder flushing for any questionable function or obvious signs and symptoms of blockage. The frequency of intermittent flushing of the bladder through these catheters during the first 24 h after prostatectomy could be on hourly interval[43] if not more frequent and undoubtedly can be overwhelming for both the patients and medical personnel. Hence, exploring a method of CBI that will eliminate or reduce the frequency of intermittent flushing of the bladder could only have been a welcomed addition to the postoperative management of these patients at that point in time.

Early publications mentioning methods of CBI in the literature include those of Loughnane[44] and Foley in Wilde et al[45]. However, a more precise description of a method of continuous bladder irrigation after prostate surgery was that of Adams[46]. Adams[46] described a “third ureter in prostatectomy”, highlighting the need of a continuous inflow of fluid into the bladder cavity, contrary to the option of intermittent washout of the bladder. This publication describes the use of a suprapubic tube connected to a reservoir of antiseptic solution for a continuous inflow of this solution into the bladder and as such, the tube serves as an additional source of fluid apart from the natural source from the kidneys through the two ureters - hence the description by the author of this additional source of fluid as a “third ureter”. Further developments in the use of continuous irrigation have been numerous and variable[16-24]. Currently, the CBI procedure is commonly performed using normal saline and a three-way Foley catheter[1,11,12,47].

Arguments for and against CBI

Post-operative bladder irrigation has been an integral part of a number of surgical procedures on the bladder and prostate and is still widely practiced and recommended in textbooks and journal articles[1-14].The reasons for advocating CBI after prostate surgery include the following: (1) prevention of clot formation and retention; (2) maintenance of the patency of the drainage catheter lumen; (3) flushing out of small clots before they become larger; and (4) bleeding control[20]. In contrast, those who advocate not using CBI after prostate surgery[25,37,48-52] give the following reasons: (1) less workload on the medical staff; (2) less financial cost to the patient; (3) easier calculation of urine output; (4) reduced risk of bladder rupture in the presence of a blocked urethral catheter; (5) urethral catheter blockage and clot retention still frequently occur even in the presence of CBI; (6) avoidance of confinement of the patient to the bed for CBI; and (7) avoidance of suprapubic pain/discomfort.

Efforts made to eliminate CBI from surgical practice

To eliminate CBI, varying approaches have been used by different authors. The various approaches to elimination of CBI can be divided into: (1) non-surgical; and (2) surgical.

Non-surgical: Use of diuretics: Some advocates of no irrigation effect CBI through the use of diuretics but without the use of an external irrigant. This concept of CBI that avoids external irrigants relies instead on the administration of high intravenous fluid in combination with diuretics that ultimately increases urine flow through the bladder[48-50,52,53]. The concern with this approach is the risk of metabolic disturbance and fluid overload in these patients, who are predominantly elderly[53].

Surgical: As mentioned in the historical background section, CBI has traditionally been intertwined with the problem of significant hemorrhage/clot formation associated with prostatic surgery. Hence, the focus of surgical modifications towards possible elimination of CBI has focused on improving hemostasis during prostate surgery.

For suprapubic prostatectomy, the approaches towards achieving better hemostasis have been variable, but in contemporary practice have commonly included packing the prostatic cavity and sutural methods of hemostasis[41,54,55]. Generally, packing the prostatic fossa has been associated with mixed success in controlling hemorrhage with a not uncommon need to periodically re-pack a few hours following surgery due to persistent bleeding. Even in cases in which packing helped achieve control of hemostasis, periodic drainage of urine to the exterior through the drainage site and later removal of the gauze pack that can be painful and might also provoke re-bleeding due to dislodgement of the already formed clot on the prostatic fossa has decreased the appeal of this method. To avoid pain and also to be prepared for possible re-packing, many urologists remove the gauze pack in the operating room with the use of anesthesia and in doing so, subject the involved patients to another trip to the operating room[41]. However, some contemporary authors have reported a more successful outcome of prostatic fossa packing with lower complication rates[56,57]. Review of some of these contemporary papers on prostatic fossa packing that reported good hemostatic control, however, showed that CBI was still routinely used[56].

Suturing the bleeding points or areas of anatomical entrance of arterial branches supplying the hyperplastic prostatic tissues is presently the dominant method of achieving hemostasis during suprapubic prostatectomy. Lower[58] and Harris[59] were among the early pioneers and advocates of sutural hemostasis. There has been a persistent effort among these early surgeons to place sutures at areas of the bladder neck where it was thought they would help achieve maximum hemostasis. Harris[59], in addition to reformation of the prostatic fossa, placed hemostatic sutures at the 5 o’clock and 7 o’clock positions of the bladder neck. In his surgical description of sutural hemostasis during suprapubic prostatectomy, Silverton[60] prefers to place “U” shaped or mattress sutures essentially to include the areas between the 3 o’clock and 5 o’clock as well as between the 7 o’clock and 9 o’clock positions. Another very significant development in the evolution of sutural hemostasis is the concept of separating the prostatic fossa from the bladder neck. This significant modification has led to a distinct direction of sutural hemostasis with many reported good surgical outcomes. Lower[58] and Harris[59] were the early pioneers that described the method of separating the prostatic fossa from the bladder neck using absorbable sutures as an approach to control hemorrhage associated with suprapubic prostatectomy. Further development of the concept of separation of the prostatic fossa from the bladder neck gave rise to the use of removable purse string sutures[61]. Malament[62] used this approach of removable purse string sutures in separating the prostatic fossa from the bladder neck and noted a significant reduction in post suprapubic prostatectomy bleeding. Other authors using the Malamet technique[34,63,64] documented good results and hence, the Malamet technique has continued to be an important option of surgical hemostasis during suprapubic prostatectomy. In a further modification of the removable purse string technique, Denis[65] additionally placed a drain in the prostatic fossa; according to the author, placement of the drain led to retraction and tamponade of the fossa and through this combination of suturing and drain placement, improved hemostasis was achieved. Contemporary use of the removable purse string technique has led to significant improvement in hemostasis; however, some of the complications that have historically plagued the technique of separating the prostatic fossa from the bladder neck, such as bladder neck stenosis/urethral stricture, periodic need for blood transfusion, clot retention and catheter blockage, have variably persisted. With this approach, there has occasionally been the need to return to operating room to remove fragments of broken purse string suture or evacuate clots, although these complications might be dependent on the surgeon or medical center[34,66]. Most contemporary authors reporting on the removable bladder neck purse string suture technique used CBI[65,67], whereas some others used intermittent bladder irrigation[34,66] and a few did not irrigate[68].

For TURP, improvements in resectoscopes, resectoscope loops, optics, energy sources, and experience of the operating surgeon have all contributed to reducing the bleeding risks historically associated with TURP[36,69]. TURP has significantly evolved over the years to the point where some authors presently perform TURP on “day-case” basis[32]. However, even for these day-case TURP with reported meticulous hemostasis, CBI was still routinely performed[32].

Another important alternative to TURP and open prostatectomy with associated better hemostasis during prostate surgery is the Holmium enucleation of the prostate (HoLEP). HoLEP is currently being acclaimed as a true endourologic equivalent of open prostatectomy, especially for large prostate glands. Blood loss is significantly reduced compared to TURP and open prostatectomy, and as such, HoLEP is associated with less or no need for blood transfusion[70-72]. This improved hemostatic control is an important factor in avoiding/minimizing CBI and can also be induced from the relatively low rate of CBI with the HoLEP technique[70,73].

Author’s modification to suprapubic prostatectomy with elimination of CBI

In contemporary practice, the most commonly recommended method of sutural hemostasis for suprapubic prostatectomy has remained the application of hemostatic stitches to the 5 and 7 o’clock positions of the bladder neck[1,74]. This method of hemostasis can be effective in controlling hemorrhage in some of these procedures; however, in many other cases, significant hemorrhage and the need for blood transfusion has remained a persistent problem[74] further fueling the continued search of a more effective method of hemostasis during suprapubic prostatectomy. Furthermore, CBI remains virtually a routine practice with this approach of application of hemostatic stitches to the 5 and 7 o’clock positions of the bladder neck[1].

It would probably be an overstatement to attribute complete elimination of CBI for suprapubic prostatectomy to any single sutural hemostatic technique. In the author’s opinion, elimination of CBI involves a combination of factors that includes, among other factors: appropriate patient selection, meticulous surgical technique especially during enucleation of prostatic adenomas, adequate sutural hemostasis, having in place a non-irrigation policy and proper Foley catheter selection[25,37].

The author’s modified method of surgical hemostasis during suprapubic prostatectomy[25,37] is based on the following intent: To maximize hemostatic suturing of all arterial branches that enter into the bladder neck and proximal prostatic capsule, in contrast to the commonly practiced application of stitches to the 5 and 7 o’clock positions, and at the same time to avoid excessive narrowing of the bladder neck that could compromise the bladder neck lumen and consequently lead to prostatic fossa or bladder neck stenosis. Following a meticulous enucleation of the prostatic adenomas (probably the most important stage of the surgery in the author’s opinion), the modified bladder neck repair/sutural hemostasis[25,37] consists of a running suture from the 1 o’clock position to the 11 o’clock position, suturing the bladder neck edge to the prostatic capsule with 2-0 polyglactin suture (Figure 1) and additional interrupted sutures applied vertically starting from the 12 o’clock position downwards to narrow the bladder neck up to the diameter of the surgeon’s index finger (Figure 2). With the index finger in the bladder neck, a 22 or 24 two-way urethral Foley catheter is inserted and guided into the bladder lumen. The balloon of the Foley catheter, which remains in the bladder lumen, is inflated to a minimum of 30 mL and placed on mild traction by tying a piece of gauze to the catheter and pushing it gently against the meatus for approximately two hours and additionally by taping the catheter to the thigh under moderate traction until the following morning with an adhesive strapping. In this way, the catheter balloon is gently pressed against the bladder neck, augmenting hemostasis and reducing reflux of blood from the prostatic fossa back to the bladder. The anterior bladder wall defect and the remainder of the incisional wound layers are closed without use of suprapubic catheters or surgical drains. Post-operative bladder irrigation is not needed and is not utilized with this approach. With these modifications, none of our patients has received a blood transfusion or CBI over the last 9 years.

Figure 1
Figure 1 Running suture from the 1 o’clock position to the 11 o’clock position, suturing the bladder neck edge to the prostatic capsule[25].
Figure 2
Figure 2 Bladder neck narrowed up to the diameter of the surgeon’s index finger[25].
Is CBI still used out of necessity or out of a routine/habitual surgical tradition?

Over the years, the surgical outcomes of TURP and suprapubic prostatectomy have definitely improved[6,25-31,33-37]. This can be attributed to a number of factors including improvements in surgical techniques and instruments. The questions then become how often is CBI used out of a long-existing surgical tradition, and in contemporary practice, how often is CBI still needed due to actual necessity? These are important questions considering the fact that authors that have reported good hemostatic control in their surgeries still continued to use CBI[56,67,69]. Although CBI is typically performed without undue complications, significant complications do occur[75] and moreover, the challenges that come with monitoring the CBI method can be overwhelming, especially in understaffed hospitals across developing countries. If postoperative CBI is to be avoided, then the key to success probably not only depends on a number of factors including meticulous surgical technique, very good hemostatic control, and use of good quality drainage catheters, but also on the implementation of a non-irrigation policy. Furthermore, it must be emphasized that the pursuit of good hemostasis should always be balanced with that of avoiding complications such as bladder neck stenosis, which can occur, for instance, in cases of significant narrowing of the bladder neck in suprapubic prostatectomy; however, this complication was more common in the older series of suprapubic prostatectomy than in more contemporary series[62,76].

Since 2006, it has been possible for this author to completely avoid CBI in cases of TURP and open prostatectomy. It is important to mention that even in rare cases of significant bleeding, it has been possible to eliminate CBI by not being in a hurry to implement this irrigation. It is also important to remember that two-way catheters used for bladder drainage have a larger drainage lumen compared to three-way catheters of the same size[52]. Hence, with adequate surgical hemostasis and with the strong aim to pursue a non-irrigation policy, it is very much feasible to avoid CBI in most cases of prostate surgery.

It can then be proposed that the key to eliminating bladder irrigation involves achieving effective surgical hemostasis and maximally reducing the presence of blood in the bladder lumen by reducing the reflux of blood from the prostatic fossa back to the bladder lumen and enhancing the immediate efflux of blood out of the bladder lumen by using good drainage catheters such as an appropriately sized two-way catheter.

However, it is very important to emphasize that changing the mindset/attitude of the surgeon towards adopting a non-irrigation policy is needed if less frequent CBI is to be achieved.


The surgical outcome of prostate surgery (TURP and open prostatectomy) has definitely improved over the years. Improved laser surgical techniques have been introduced. With these improvements, especially in the area of surgical hemostasis, it is certainly time to reconsider the routine use of CBI, which has been an integral part of prostate surgery and might have been more relevant during the evolving stages of these surgeries. This is certainly important considering the human and financial cost as well as the potential complications of CBI, among other disadvantages. Having in place a policy aimed at avoiding the routine use of CBI is also needed to achieve less frequent CBI.


P- Reviewer: Donkov I, Naselli A S- Editor: Qiu S L- Editor: A E- Editor: Wu HL

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