Published online Nov 24, 2014. doi: 10.5410/wjcu.v3.i3.344
Revised: May 28, 2014
Accepted: September 6, 2014
Published online: November 24, 2014
Core tip: In this review, we described the vitamin C deficiency in maintenance hemodialysis patients and its effects on anti-oxidation, anti-inflammation, pro-oxidation and secondary hyperparathyroidism. In addition, we described the possible potential value of vitamin C in anemia, and the side effects of over-doses of vitamin C supplementation in this particular population.