Copyright ©The Author(s) 2015.
World J Clin Pediatr. May 8, 2015; 4(2): 19-24
Published online May 8, 2015. doi: 10.5409/wjcp.v4.i2.19
Table 1 Conditions mimicking childhood and neonatal appendicitis (modified from ref.[8])
ConditionDiagnostic clues
GastroenteritisContinuous abdominal pain
Poor clinical condition with mild or no dehydration, continuous, focal abdominal pain, and lack of movement in infants and young children distinguishes appendicitis from gastroenteritis Acute appendicitis is more common during viral epidemics and bacterial gastroenteritis[44]
Upper respiratory tract infection1The presence of concomitant signs of upper respiratory infection are common in toddlers and does not rule out the possibility of appendicitis
PneumoniaBasal pneumonia may mimic appendicitis pain[45] Simultaneous pneumococcal pneumonia and appendicitis is well reported in the literature[46]
SepsisAn acute appendicitis should be suspected and ruled out in any case of sepsis associated with abdominal pain and or abdominal tenderness[47]
Urinary tract infectionPeritoneal inflammation may cause voiding disturbances and bladder symptoms[48]
Blunt abdominal traumaAcute appendicitis may be associated with blunt abdominal trauma[49-51]
IntussceptionAbdominal US is highly operator dependent In presence of fever, localized pain and guarding in infants and young children, appendicitis should be ruled out[52]
NECWith a history of NEC outside prematurity and signs of abdominal cellulitis, neonatal appendicitis should be ruled out[53]